about
Drug discovery beyond the rule of 5 - Opportunities and challenges.Targeting intracellular protein-protein interactions with cell-permeable cyclic peptides.MacroEvoLution: A New Method for the Rapid Generation of Novel Scaffold-Diverse Macrocyclic LibrariesTransporter effects on cell permeability in drug delivery.Design, synthesis, and evaluation of a novel series of macrocyclic inhibitors of norovirus 3CL protease.Progress towards the broad use of non-peptide synthetic macrocycles in drug discovery.Two-Step Synthesis of Complex Artificial Macrocyclic Compounds.Highly Conformationally Restricted Cyclopropane Tethers with Three-Dimensional Structural Diversity Drastically Enhance the Cell Permeability of Cyclic Peptides.From Peptides to Peptidomimetics: A Strategy Based on the Structural Features of Cyclopropane.Medium-Sized-Ring Analogues of Dibenzodiazepines by a Conformationally Induced Smiles Ring Expansion.Generation of a cell-permeable cycloheptapeptidyl inhibitor against the peptidyl-prolyl isomerase Pin1.Conformational Sampling of Macrocyclic Drugs in Different Environments: Can We Find the Relevant Conformations?A molecular mechanism for the enzymatic methylation of nitrogen atoms within peptide bonds
P2860
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P2860
description
2016 nî lūn-bûn
@nan
2016年の論文
@ja
2016年論文
@yue
2016年論文
@zh-hant
2016年論文
@zh-hk
2016年論文
@zh-mo
2016年論文
@zh-tw
2016年论文
@wuu
2016年论文
@zh
2016年论文
@zh-cn
name
Cell permeability beyond the rule of 5.
@ast
Cell permeability beyond the rule of 5.
@en
type
label
Cell permeability beyond the rule of 5.
@ast
Cell permeability beyond the rule of 5.
@en
prefLabel
Cell permeability beyond the rule of 5.
@ast
Cell permeability beyond the rule of 5.
@en
P50
P1476
Cell permeability beyond the rule of 5
@en
P2093
Jan Kihlberg
P356
10.1016/J.ADDR.2016.03.013
P407
P577
2016-04-09T00:00:00Z