Mapping the conformation of a client protein through the Hsp70 functional cycle.
about
Engineering and Evolution of Molecular Chaperones and Protein Disaggregases with Enhanced ActivityCo- and Post-Translational Protein Folding in the ERCapturing a Dynamic Chaperone-Substrate Interaction Using NMR-Informed Molecular ModelingHdeB chaperone activity is coupled to its intrinsic dynamic properties.Hsp70 biases the folding pathways of client proteins.Dynamical Structures of Hsp70 and Hsp70-Hsp40 Complexes.Structural basis of synaptic vesicle assembly promoted by α-synuclein.Conformational heterogeneity in the Hsp70 chaperone-substrate ensemble: identified from analysis of NMR-detected titration data.Chaperone-client interactions: Non-specificity engenders multifunctionality.Promiscuous binding by Hsp70 results in conformational heterogeneity and fuzzy chaperone-substrate ensembles.X-Linked Inhibitor of Apoptosis Protein (XIAP) is a Client of Heat Shock Protein 70 (Hsp70) and a Biomarker of its Inhibition.Thermodynamic Bounds on the Ultra- and Infra-affinity of Hsp70 for Its Substrates.An enhanced sensitivity methyl 1H triple-quantum pulse scheme for measuring diffusion constants of macromolecules.Domain Mapping of Heat Shock Protein 70 Reveals That Glutamic Acid 446 and Arginine 447 Are Critical for Regulating Superoxide Dismutase 2 Function.Conserved conformational selection mechanism of Hsp70 chaperone-substrate interactions.Evaluating the influence of initial magnetization conditions on extracted exchange parameters in NMR relaxation experiments: applications to CPMG and CEST.Longitudinal relaxation optimized amide 1H-CEST experiments for studying slow chemical exchange processes in fully protonated proteins.
P2860
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P2860
Mapping the conformation of a client protein through the Hsp70 functional cycle.
description
2015 nî lūn-bûn
@nan
2015年の論文
@ja
2015年論文
@yue
2015年論文
@zh-hant
2015年論文
@zh-hk
2015年論文
@zh-mo
2015年論文
@zh-tw
2015年论文
@wuu
2015年论文
@zh
2015年论文
@zh-cn
name
Mapping the conformation of a client protein through the Hsp70 functional cycle.
@ast
Mapping the conformation of a client protein through the Hsp70 functional cycle.
@en
type
label
Mapping the conformation of a client protein through the Hsp70 functional cycle.
@ast
Mapping the conformation of a client protein through the Hsp70 functional cycle.
@en
prefLabel
Mapping the conformation of a client protein through the Hsp70 functional cycle.
@ast
Mapping the conformation of a client protein through the Hsp70 functional cycle.
@en
P2860
P356
P1476
Mapping the conformation of a client protein through the Hsp70 functional cycle.
@en
P2093
Ashok Sekhar
Rina Rosenzweig
P2860
P304
10395-10400
P356
10.1073/PNAS.1508504112
P407
P577
2015-08-03T00:00:00Z