Distinct neural stem cell populations give rise to disparate brain tumors in response to N-MYC. - Wikidata - awgldk - TriplyDB

Distinct neural stem cell populations give rise to disparate brain tumors in response to N-MYC.

Distinct neural stem cell populations give rise to disparate brain tumors in response to N-MYC.

http://www.wikidata.org/entity/Q35989886

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Voltage-gated potassium channel EAG2 controls mitotic entry and tumor growth in medulloblastoma via regulating cell volume dynamics Medulloblastoma stem cells: Promising targets in medulloblastoma therapy Role of SOX family of transcription factors in central nervous system tumors Histone H3 mutations--a special role for H3.3 in tumorigenesis?FBW7 suppression leads to SOX9 stabilization and increased malignancy in medulloblastoma Targeting SOX9 for degradation to inhibit chemoresistance, metastatic spread, and recurrence In vivo Mn-enhanced MRI for early tumor detection and growth rate analysis in a mouse medulloblastoma model.Contribution of tumor heterogeneity in a new animal model of CNS tumors.The prenatal origins of cancer PTEN regulates glioblastoma oncogenesis through chromatin-associated complexes of DAXX and histone H3.3.MYCN amplification predicts poor outcome for patients with supratentorial primitive neuroectodermal tumors of the central nervous system MYC Deregulation in Primary Human Cancers.TLR9 is critical for glioma stem cell maintenance and targeting.Targeting Epigenetic Pathways in the Treatment of Pediatric Diffuse (High Grade) Gliomas.Deregulated proliferation and differentiation in brain tumors.Overcoming resistance to Sonic Hedgehog inhibition by targeting p90 ribosomal S6 kinase in pediatric medulloblastoma.Molecular and in vivo characterization of cancer-propagating cells derived from MYCN-dependent medulloblastoma Histone H3.3 and cancer: A potential reader connection.Expression of MYCN in Multipotent Sympathoadrenal Progenitors Induces Proliferation and Neural Differentiation, but Is Not Sufficient for Tumorigenesis.Caspr4 interaction with LNX2 modulates the proliferation and neuronal differentiation of mouse neural progenitor cells.EGFR Mutation Promotes Glioblastoma through Epigenome and Transcription Factor Network Remodeling.The role of Sox genes in lung morphogenesis and cancer.Unique genetic and epigenetic mechanisms driving paediatric diffuse high-grade glioma.MicroRNA Biogenesis and Hedgehog-Patched Signaling Cooperate to Regulate an Important Developmental Transition in Granule Cell Development.The role of stem cells and progenitors in the genesis of medulloblastoma Stem cells expanded from the human embryonic hindbrain stably retain regional specification and high neurogenic potency The miR-223/nuclear factor I-A axis regulates glial precursor proliferation and tumorigenesis in the CNS.Landscape of DNA virus associations across human malignant cancers: analysis of 3,775 cases using RNA-Seq Differential transformation capacity of neuro-glial progenitors during development MiR-145 functions as a tumor-suppressive RNA by targeting Sox9 and adducin 3 in human glioma cells.Neuroblastoma and MYCN Oligodendrocyte/type-2 astrocyte progenitor cells and glial-restricted precursor cells generate different tumor phenotypes in response to the identical oncogenes.Role of MYC in Medulloblastoma.Medulloblastomics: the end of the beginning.Molecular variants and mutations in medulloblastoma.Characterization of pancreatic glucagon-producing tumors and pituitary gland tumors in transgenic mice overexpressing MYCN in hGFAP-positive cells.Paediatric and adult glioblastoma: multiform (epi)genomic culprits emerge.The SOX family of genes in cancer development: biological relevance and opportunities for therapy.Stem cell research points the way to the cell of origin for intracranial germ cell tumours.What underlies the diversity of brain tumors?

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Distinct neural stem cell populations give rise to disparate brain tumors in response to N-MYC.

http://www.wikidata.org/entity/Q35989886

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Distinct neural stem cell popu ...... n tumors in response to N-MYC.

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Distinct neural stem cell popu ...... n tumors in response to N-MYC.

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Distinct neural stem cell popu ...... n tumors in response to N-MYC.

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J.CCR.2012.04.012

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Distinct neural stem cell popu ...... n tumors in response to N-MYC.

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Christopher S Hackett

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Jasmine Lau

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Joanna J Phillips

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Justin Chen

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Michael D Taylor

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Paul A Northcott

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Vasil Savov

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P2860

Significance analysis of microarrays applied to the ionizing radiation response

Molecular subgroups of medulloblastoma: the current consensus

The miR-17/92 polycistron is up-regulated in sonic hedgehog-driven medulloblastomas and induced by N-myc in sonic hedgehog-treated cerebellar neural precursors

Differential expression and prognostic significance of SOX genes in pediatric medulloblastoma and ependymoma identified by microarray analysis

Comprehensive genomic characterization defines human glioblastoma genes and core pathways

Subventricular zone astrocytes are neural stem cells in the adult mammalian brain

Effects of oncogenic mutations in Smoothened and Patched can be reversed by cyclopamine

N-myc is essential during neurogenesis for the rapid expansion of progenitor cell populations and the inhibition of neuronal differentiation

Outcome prediction in pediatric medulloblastoma based on DNA copy-number aberrations of chromosomes 6q and 17q and the MYC and MYCN loci

The oligodendroglial lineage marker OLIG2 is universally expressed in diffuse gliomas

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10.1016/J.CCR.2012.04.012

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Fredrik J Swartling

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2012-05-01T00:00:00Z

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225059980

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22624711

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3360885

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