Energy coupling in DNA gyrase and the mechanism of action of novobiocin.
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Crystal structures of Escherichia coli topoisomerase IV ParE subunit (24 and 43 kilodaltons): a single residue dictates differences in novobiocin potency against topoisomerase IV and DNA gyraseBiochemistry of homologous recombination in Escherichia coliDNA gyrase, topoisomerase IV, and the 4-quinolonesTargeting DNA topoisomerase II in cancer chemotherapyA model for the mechanism of strand passage by DNA gyraseA monoclonal antibody that inhibits mycobacterial DNA gyrase by a novel mechanism.Dimerization of Escherichia coli DNA-gyrase B provides a structural mechanism for activating the ATPase catalytic centerAn open conformation of the Thermus thermophilus gyrase B ATP-binding domainStructure of the topoisomerase II ATPase region and its mechanism of inhibition by the chemotherapeutic agent ICRF-187Structural basis for gate-DNA recognition and bending by type IIA topoisomerasesDifferential ATP binding and intrinsic ATP hydrolysis by amino-terminal domains of the yeast Mlh1 and Pms1 proteins.A novel high-throughput cell-based assay aimed at identifying inhibitors of DNA metabolism in bacteriaA classification based framework for quantitative description of large-scale microarray data.The ancestral role of ATP hydrolysis in type II topoisomerases: prevention of DNA double-strand breaks.Components of SurA required for outer membrane biogenesis in uropathogenic Escherichia coli.Discovery, characterization and comparison of inhibitors of Bacillus anthracis and Staphylococcus aureus replicative DNA helicases.Modulation of gyrase-mediated DNA cleavage and cell killing by ATP.Cloning and characterization of a DNA gyrase A gene from Escherichia coli that confers clinical resistance to 4-quinolones.Gyrase inhibitors and thymine starvation disrupt the normal pattern of plasmid RK2 localization in Escherichia coliA high-throughput fluorescence polarization assay for inhibitors of gyrase BNovobiocin inhibits passive chromatin assembly in vitro.A topoisomerase from Escherichia coli related to DNA gyraseDNA gyrase: purification and catalytic properties of a fragment of gyrase B proteinHomologous pairing in genetic recombination: complexes of recA protein and DNA.The interaction of drugs with DNA gyrase: a model for the molecular basis of quinolone action.Complementation of a Treponema denticola flgE mutant with a novel coumermycin A1-resistant T. denticola shuttle vector system.Bacillus subtilis deoxyribonucleic acid gyraseStructure-based design and screening of inhibitors for an essential bacterial GTPase, Der.Exploiting bacterial DNA gyrase as a drug target: current state and perspectives.The RAD3 gene of Saccharomyces cerevisiae encodes a DNA-dependent ATPaseDNA-strand exchange promoted by RecA protein in the absence of ATP: implications for the mechanism of energy transduction in protein-promoted nucleic acid transactions.DNA gyrase: structure and function.In memoriam: PNAS Editor-in-Chief Nicholas R. Cozzarelli (1938-2006)DNA topoisomerase II as a target for cancer chemotherapy.Alteration of Escherichia coli topoisomerase IV to novobiocin resistance.Roles of novobiocin-sensitive topoisomerases in chloroplast DNA replication in Chlamydomonas reinhardtiiProgress in the discovery of treatments for C. difficile infection: A clinical and medicinal chemistry review.The effect of Escherichia coli Uvr protein binding on the topology of supercoiled DNA.Quinolone resistance mutations in topoisomerase IV: relationship to the flqA locus and genetic evidence that topoisomerase IV is the primary target and DNA gyrase is the secondary target of fluoroquinolones in Staphylococcus aureus.Discovery of ATP-Competitive Inhibitors of tRNAIle Lysidine Synthetase (TilS) by High-Throughput Screening.
P2860
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P2860
Energy coupling in DNA gyrase and the mechanism of action of novobiocin.
description
1978 nî lūn-bûn
@nan
1978年の論文
@ja
1978年論文
@yue
1978年論文
@zh-hant
1978年論文
@zh-hk
1978年論文
@zh-mo
1978年論文
@zh-tw
1978年论文
@wuu
1978年论文
@zh
1978年论文
@zh-cn
name
Energy coupling in DNA gyrase and the mechanism of action of novobiocin.
@ast
Energy coupling in DNA gyrase and the mechanism of action of novobiocin.
@en
type
label
Energy coupling in DNA gyrase and the mechanism of action of novobiocin.
@ast
Energy coupling in DNA gyrase and the mechanism of action of novobiocin.
@en
prefLabel
Energy coupling in DNA gyrase and the mechanism of action of novobiocin.
@ast
Energy coupling in DNA gyrase and the mechanism of action of novobiocin.
@en
P2093
P2860
P356
P1476
Energy coupling in DNA gyrase and the mechanism of action of novobiocin.
@en
P2093
Cozzarelli NR
Higgins NP
Peebles CL
P2860
P304
P356
10.1073/PNAS.75.10.4838
P407
P577
1978-10-01T00:00:00Z