Selective expression of Parkinson's disease-related Leucine-rich repeat kinase 2 G2019S missense mutation in midbrain dopaminergic neurons impairs dopamine release and dopaminergic gene expression.
about
Age-dependent dopamine transporter dysfunction and Serine129 phospho-α-synuclein overload in G2019S LRRK2 mice.Overexpression of Parkinson's Disease-Associated Mutation LRRK2 G2019S in Mouse Forebrain Induces Behavioral Deficits and α-Synuclein PathologyConditional deletion of Ndufs4 in dopaminergic neurons promotes Parkinson's disease-like non-motor symptoms without loss of dopamine neurons.Review: Parkinson's disease: from synaptic loss to connectome dysfunction.Models of LRRK2-Associated Parkinson's Disease.LRRK2 phosphorylates pre-synaptic N-ethylmaleimide sensitive fusion (NSF) protein enhancing its ATPase activity and SNARE complex disassembling rate.Age-Dependent Dopaminergic Neurodegeneration and Impairment of the Autophagy-Lysosomal Pathway in LRRK-Deficient Mice.Robust kinase- and age-dependent dopaminergic and norepinephrine neurodegeneration in LRRK2 G2019S transgenic mice.Dopamine D2 receptor-mediated neuroprotection in a G2019S Lrrk2 genetic model of Parkinson's disease.
P2860
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P2860
Selective expression of Parkinson's disease-related Leucine-rich repeat kinase 2 G2019S missense mutation in midbrain dopaminergic neurons impairs dopamine release and dopaminergic gene expression.
description
2015 nî lūn-bûn
@nan
2015年の論文
@ja
2015年学术文章
@wuu
2015年学术文章
@zh-cn
2015年学术文章
@zh-hans
2015年学术文章
@zh-my
2015年学术文章
@zh-sg
2015年學術文章
@yue
2015年學術文章
@zh
2015年學術文章
@zh-hant
name
Selective expression of Parkin ...... dopaminergic gene expression.
@ast
Selective expression of Parkin ...... dopaminergic gene expression.
@en
type
label
Selective expression of Parkin ...... dopaminergic gene expression.
@ast
Selective expression of Parkin ...... dopaminergic gene expression.
@en
prefLabel
Selective expression of Parkin ...... dopaminergic gene expression.
@ast
Selective expression of Parkin ...... dopaminergic gene expression.
@en
P2093
P2860
P50
P356
P1476
Selective expression of Parkin ...... d dopaminergic gene expression
@en
P2093
Chengsong Xie
David M Lovinger
Guoxiang Liu
Jinhui Ding
Kelly M Lohr
Loukia Parisiadou
Xinglong Gu
P2860
P304
P356
10.1093/HMG/DDV249
P577
2015-06-29T00:00:00Z