Breaking the HAC Barrier: histone H3K9 acetyl/methyl balance regulates CENP-A assembly.
about
A new generation of human artificial chromosomes for functional genomics and gene therapyTargeting histone methyltransferases and demethylases in clinical trials for cancer therapyA pathway from chromosome transfer to engineering resulting in human and mouse artificial chromosomes for a variety of applications to bio-medical challengesSunflower centromeres consist of a centromere-specific LINE and a chromosome-specific tandem repeatFormation of functional CENP-B boxes at diverse locations in repeat units of centromeric DNA in New World monkeysComparative analysis of tandem repeats from hundreds of species reveals unique insights into centromere evolutionA cell-free CENP-A assembly system defines the chromatin requirements for centromere maintenance.Putting CENP-A in its placeEsperanto for histones: CENP-A, not CenH3, is the centromeric histone H3 variantInternal modifications in the CENP-A nucleosome modulate centromeric dynamics.A cell-free system for functional centromere and kinetochore assemblyThe centromere: chromatin foundation for the kinetochore machinery.NET23/STING promotes chromatin compaction from the nuclear envelopeA portable BRCA1-HAC (human artificial chromosome) module for analysis of BRCA1 tumor suppressor function.A new assay for measuring chromosome instability (CIN) and identification of drugs that elevate CIN in cancer cellsThe centromere: epigenetic control of chromosome segregation during mitosisGenerating a transgenic mouse line stably expressing human MHC surface antigen from a HAC carrying multiple genomic BACs.Stable complex formation of CENP-B with the CENP-A nucleosome.Generation of a conditionally self-eliminating HAC gene delivery vector through incorporation of a tTAVP64 expression cassette.Epigenetic engineering shows that a human centromere resists silencing mediated by H3K27me3/K9me3CENP-C and CENP-I are key connecting factors for kinetochore and CENP-A assemblyTranscription in the maintenance of centromere chromatin identity.Nap1 regulates proper CENP-B binding to nucleosomes.CENP-B box, a nucleotide motif involved in centromere formation, occurs in a New World monkey.Re-engineering an alphoid(tetO)-HAC-based vector to enable high-throughput analyses of gene function.KAT7/HBO1/MYST2 Regulates CENP-A Chromatin Assembly by Antagonizing Suv39h1-Mediated Centromere Inactivation.Protecting a transgene expression from the HAC-based vector by different chromatin insulators.Epigenetic engineering reveals a balance between histone modifications and transcription in kinetochore maintenance.Temporal control of epigenetic centromere specification.HACking the centromere chromatin code: insights from human artificial chromosomes.CENP-A: the key player behind centromere identity, propagation, and kinetochore assemblyHuman artificial chromosome-based gene delivery vectors for biomedicine and biotechnology.Anarchic centromeres: deciphering order from apparent chaos.Engineering of plant chromosomes.Genetic and epigenetic regulation of centromeres: a look at HAC formation.Centromeric chromatin and its dynamics in plants.Centromere Silencing Mechanisms.A Molecular View of Kinetochore Assembly and Function.SIRT6 deacetylates H3K18ac at pericentric chromatin to prevent mitotic errors and cellular senescence.Kinetochore assembly and function through the cell cycle.
P2860
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P2860
Breaking the HAC Barrier: histone H3K9 acetyl/methyl balance regulates CENP-A assembly.
description
2012 nî lūn-bûn
@nan
2012年の論文
@ja
2012年論文
@yue
2012年論文
@zh-hant
2012年論文
@zh-hk
2012年論文
@zh-mo
2012年論文
@zh-tw
2012年论文
@wuu
2012年论文
@zh
2012年论文
@zh-cn
name
Breaking the HAC Barrier: histone H3K9 acetyl/methyl balance regulates CENP-A assembly.
@ast
Breaking the HAC Barrier: histone H3K9 acetyl/methyl balance regulates CENP-A assembly.
@en
type
label
Breaking the HAC Barrier: histone H3K9 acetyl/methyl balance regulates CENP-A assembly.
@ast
Breaking the HAC Barrier: histone H3K9 acetyl/methyl balance regulates CENP-A assembly.
@en
prefLabel
Breaking the HAC Barrier: histone H3K9 acetyl/methyl balance regulates CENP-A assembly.
@ast
Breaking the HAC Barrier: histone H3K9 acetyl/methyl balance regulates CENP-A assembly.
@en
P2093
P2860
P356
P1433
P1476
Breaking the HAC Barrier: histone H3K9 acetyl/methyl balance regulates CENP-A assembly.
@en
P2093
Hiroshi Kimura
Hiroshi Masumoto
Jan H Bergmann
Jun-ichirou Ohzeki
Megumi Nakano
Natalay Kouprina
Vladimir Larionov
Vladimir N Noskov
P2860
P304
P356
10.1038/EMBOJ.2012.82
P407
P577
2012-04-03T00:00:00Z