TGF-beta switches from tumor suppressor to prometastatic factor in a model of breast cancer progression.
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Expression of GATA3 in MDA-MB-231 triple-negative breast cancer cells induces a growth inhibitory response to TGFßThe use of cystatin C to inhibit epithelial-mesenchymal transition and morphological transformation stimulated by transforming growth factor-beta.Transforming growth factor-beta1, transforming growth factor-beta2, and transforming growth factor-beta3 enhance ovarian cancer metastatic potential by inducing a Smad3-dependent epithelial-to-mesenchymal transitionProgrammed cell death protein-1/programmed cell death ligand-1 pathway inhibition and predictive biomarkers: understanding transforming growth factor-beta roleTransient tumor-fibroblast interactions increase tumor cell malignancy by a TGF-Beta mediated mechanism in a mouse xenograft model of breast cancerReal-time motion analysis reveals cell directionality as an indicator of breast cancer progressionA cytokine-neutralizing antibody as a structural mimetic of 2 receptor interactionsRole of TGFβ in regulation of the tumor microenvironment and drug delivery (review)TGFβ Signaling in Tumor Initiation, Epithelial-to-Mesenchymal Transition, and MetastasisDoxorubicin in combination with a small TGFbeta inhibitor: a potential novel therapy for metastatic breast cancer in mouse modelsProteome-wide profiling of the MCF10AT breast cancer progression modelTwenty-five years of PTHrP progress: from cancer hormone to multifunctional cytokine.Supervillin reorganizes the actin cytoskeleton and increases invadopodial efficiency.Smad4-expression is decreased in breast cancer tissues: a retrospective study.Delineating genetic alterations for tumor progression in the MCF10A series of breast cancer cell lines.p130Cas is required for mammary tumor growth and transforming growth factor-beta-mediated metastasis through regulation of Smad2/3 activity.Two faces of TGF-beta1 in breast cancer.TGF-beta and the Smad signaling pathway support transcriptomic reprogramming during epithelial-mesenchymal cell transitionA novel function for p21Cip1 and acetyltransferase p/CAF as critical transcriptional regulators of TGFβ-mediated breast cancer cell migration and invasion.A microRNA expression signature for cervical cancer prognosis.Progression of BRAF-induced thyroid cancer is associated with epithelial-mesenchymal transition requiring concomitant MAP kinase and TGFβ signaling.Distinct mechanisms of TGF-beta1-mediated epithelial-to-mesenchymal transition and metastasis during skin carcinogenesis.Rapamycin enhances the antiproliferative effect of transforming growth factor-β on MCF-7 human breast cancer cellsAn integrated genomic approach identifies persistent tumor suppressive effects of transforming growth factor-β in human breast cancerCathepsin B is the driving force of esophageal cell invasion in a fibroblast-dependent manner.Targeting the Transforming Growth Factor-beta pathway inhibits human basal-like breast cancer metastasis.TGFbeta signaling supports survival and metastasis of endometrial cancer cells.The microRNA-23b/27b/24 cluster promotes breast cancer lung metastasis by targeting metastasis-suppressive gene prosaposin.SMAD4 is a potential prognostic marker in human breast carcinomas.Genetic suppression of inflammation blocks the tumor-promoting effects of TGF-β in gastric tissue.Perspectives on tissue interactions in development and disease.Tgf-beta signaling pathway in lung adenocarcinoma invasion.Disabled-2 downregulation promotes epithelial-to-mesenchymal transitionLEF-1 and TCF4 expression correlate inversely with survival in colorectal cancerSerum starvation regulates E-cadherin upregulation via activation of c-Src in non-small-cell lung cancer A549 cells.Gene expression profiling of cancer progression reveals intrinsic regulation of transforming growth factor-beta signaling in ErbB2/Neu-induced tumors from transgenic mice.A potential anti-tumor herbal medicine, Corilagin, inhibits ovarian cancer cell growth through blocking the TGF-β signaling pathways.Adaptive and maladptive effects of SMAD3 signaling in the adult heart after hemodynamic pressure overloadingLoss of TGF-beta type II receptor in fibroblasts promotes mammary carcinoma growth and invasion through upregulation of TGF-alpha-, MSP- and HGF-mediated signaling networksLysyl oxidase contributes to mechanotransduction-mediated regulation of transforming growth factor-β signaling in breast cancer cells.
P2860
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P2860
TGF-beta switches from tumor suppressor to prometastatic factor in a model of breast cancer progression.
description
2003 nî lūn-bûn
@nan
2003年の論文
@ja
2003年論文
@yue
2003年論文
@zh-hant
2003年論文
@zh-hk
2003年論文
@zh-mo
2003年論文
@zh-tw
2003年论文
@wuu
2003年论文
@zh
2003年论文
@zh-cn
name
TGF-beta switches from tumor s ...... of breast cancer progression.
@ast
TGF-beta switches from tumor s ...... of breast cancer progression.
@en
type
label
TGF-beta switches from tumor s ...... of breast cancer progression.
@ast
TGF-beta switches from tumor s ...... of breast cancer progression.
@en
prefLabel
TGF-beta switches from tumor s ...... of breast cancer progression.
@ast
TGF-beta switches from tumor s ...... of breast cancer progression.
@en
P2093
P2860
P356
P1476
TGF-beta switches from tumor s ...... l of breast cancer progression
@en
P2093
Binwu Tang
Fred R Miller
Miriam R Anver
Steven J Santner
Timberly Booker
P2860
P304
P356
10.1172/JCI200318899
P407
P577
2003-10-01T00:00:00Z