Selective increase of two ABC drug efflux transporters at the blood-spinal cord barrier suggests induced pharmacoresistance in ALS.
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Immune responses at brain barriers and implications for brain development and neurological function in later lifeBlood-CNS Barrier Impairment in ALS patients versus an animal modelBlood-Brain Barrier and Breast Cancer Resistance Protein: A Limit to the Therapy of CNS Tumors and Neurodegenerative DiseasesCNS-targeted glucocorticoid reduces pathology in mouse model of amyotrophic lateral sclerosisModelling the endothelial blood-CNS barriers: a method for the production of robust in vitro models of the rat blood-brain barrier and blood-spinal cord barrier.Inhibiting drug efflux transporters improves efficacy of ALS therapeuticsRole of the breast cancer resistance protein (BCRP/ABCG2) in drug transport--an update.ABC transporter-driven pharmacoresistance in Amyotrophic Lateral Sclerosis.Regulation of ABC transporters at the blood-brain barrier.Small Molecules in Development for the Treatment of Spinal Muscular Atrophy.In Vivo Imaging of Human MDR1 Transcription in the Brain and Spine of MDR1-Luciferase Reporter Mice.Regulation of ABC efflux transporters at blood-brain barrier in health and neurological disorders.The dual cyclooxygenase/5-lipoxygenase inhibitor licofelone attenuates p-glycoprotein-mediated drug resistance in the injured spinal cord.Neurovascular unit in chronic pain.Ceramide 1-Phosphate Increases P-Glycoprotein Transport Activity at the Blood-Brain Barrier via Prostaglandin E2 Signaling.A retrospective review of the progress in amyotrophic lateral sclerosis drug discovery over the last decade and a look at the latest strategies.Non-neuronal Cells in ALS: Role of Glial, Immune cells and Blood-CNS Barriers.ABC transporters at the blood-brain barrier.Effect of Disease Pathologies on Transporter Expression and Function.Transporters as Drug Targets in Neurological DiseasesAstrocytes drive upregulation of the multidrug resistance transporter ABCB1 (P-Glycoprotein) in endothelial cells of the blood-brain barrier in mutant superoxide dismutase 1-linked amyotrophic lateral sclerosis.Neuroinflammation as the proximate cause of signature pathogenic pattern progression in amyotrophic lateral sclerosis, AIDS, and multiple sclerosisSelective induction of P-glycoprotein at the CNS barriers during symptomatic stage of an ALS animal model.Lysophosphatidic acid and amitriptyline signal through LPA1R to reduce P-glycoprotein transport at the blood-brain barrier.The "Frail" Brain Blood Barrier in Neurodegenerative Diseases: Role of Early Disruption of Endothelial Cell-to-Cell Connections
P2860
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P2860
Selective increase of two ABC drug efflux transporters at the blood-spinal cord barrier suggests induced pharmacoresistance in ALS.
description
2012 nî lūn-bûn
@nan
2012年の論文
@ja
2012年論文
@yue
2012年論文
@zh-hant
2012年論文
@zh-hk
2012年論文
@zh-mo
2012年論文
@zh-tw
2012年论文
@wuu
2012年论文
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2012年论文
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name
Selective increase of two ABC ...... ced pharmacoresistance in ALS.
@ast
Selective increase of two ABC ...... ced pharmacoresistance in ALS.
@en
type
label
Selective increase of two ABC ...... ced pharmacoresistance in ALS.
@ast
Selective increase of two ABC ...... ced pharmacoresistance in ALS.
@en
prefLabel
Selective increase of two ABC ...... ced pharmacoresistance in ALS.
@ast
Selective increase of two ABC ...... ced pharmacoresistance in ALS.
@en
P2093
P2860
P1476
Selective increase of two ABC ...... ced pharmacoresistance in ALS.
@en
P2093
Christopher Campos
Davide Trotti
Dena A Jacob
Michael R Jablonski
Nicholas J Maragakis
Piera Pasinelli
P2860
P304
P356
10.1016/J.NBD.2012.03.040
P577
2012-04-11T00:00:00Z