The amino acid sensor GCN2 inhibits inflammatory responses to apoptotic cells promoting tolerance and suppressing systemic autoimmunity.
about
The Kynurenine Pathway Is a Double-Edged Sword in Immune-Privileged Sites and in Cancer: Implications for ImmunotherapyApoptotic cell responses in the splenic marginal zone: a paradigm for immunologic reactions to apoptotic antigens with implications for autoimmunityIDO in the Tumor Microenvironment: Inflammation, Counter-Regulation, and ToleranceIDO2 Modulates T Cell-Dependent Autoimmune Responses through a B Cell-Intrinsic Mechanism.The stress kinase GCN2 does not mediate suppression of antitumor T cell responses by tryptophan catabolism in experimental melanomas.Immunometabolism in systemic lupus erythematosus.Dysfunctional T cell metabolism in the tumor microenvironment.The many ways tissue phagocytes respond to dying cells.IDO, PTEN-expressing Tregs and control of antigen-presentation in the murine tumor microenvironment.Anti-inflammatory Mechanisms Triggered by Apoptotic Cells during Their Clearance.The modulation of enzyme indoleamine 2,3-dioxygenase from dendritic cells for the treatment of type 1 diabetes mellitus.Apoptotic Cells Induced Signaling for Immune Homeostasis in Macrophages and Dendritic Cells.IDO1 in cancer: a Gemini of immune checkpoints.LC3-Associated Phagocytosis and Inflammation.Modulating Tumor Immunology by Inhibiting Indoleamine 2,3-Dioxygenase (IDO): Recent Developments and First Clinical Experiences.Amino Acid Sensing via General Control Nonderepressible-2 Kinase and Immunological Programming.The spectrum of T cell metabolism in health and disease.Maintaining a Healthy Proteome during Oxidative Stress.Functions and Signaling Pathways of Amino Acids in Intestinal Inflammation.GCN2 deficiency ameliorates doxorubicin-induced cardiotoxicity by decreasing cardiomyocyte apoptosis and myocardial oxidative stress.GCN2 controls the cellular checkpoint: potential target for regulating inflammation.Targeting the IDO1 pathway in cancer: from bench to bedside
P2860
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P2860
The amino acid sensor GCN2 inhibits inflammatory responses to apoptotic cells promoting tolerance and suppressing systemic autoimmunity.
description
2015 nî lūn-bûn
@nan
2015年の論文
@ja
2015年論文
@yue
2015年論文
@zh-hant
2015年論文
@zh-hk
2015年論文
@zh-mo
2015年論文
@zh-tw
2015年论文
@wuu
2015年论文
@zh
2015年论文
@zh-cn
name
The amino acid sensor GCN2 inh ...... ressing systemic autoimmunity.
@ast
The amino acid sensor GCN2 inh ...... ressing systemic autoimmunity.
@en
type
label
The amino acid sensor GCN2 inh ...... ressing systemic autoimmunity.
@ast
The amino acid sensor GCN2 inh ...... ressing systemic autoimmunity.
@en
prefLabel
The amino acid sensor GCN2 inh ...... ressing systemic autoimmunity.
@ast
The amino acid sensor GCN2 inh ...... ressing systemic autoimmunity.
@en
P2093
P2860
P50
P356
P1476
The amino acid sensor GCN2 inh ...... ressing systemic autoimmunity.
@en
P2093
Buvana Ravishankar
Haiyun Liu
Kapil Chaudhary
Michael P Madaio
P2860
P304
10774-10779
P356
10.1073/PNAS.1504276112
P407
P577
2015-08-10T00:00:00Z