Optimization of N-aryl-6-methoxy-1,2,3,4-tetrahydroquinolines as tubulin polymerization inhibitors

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Synthesis, biological evaluation, and physicochemical property assessment of 4-substituted 2-phenylaminoquinazolines as Mer tyrosine kinase inhibitors

P2860

Q37036648-2E673262-24D9-4E2E-BF08-586FC6771244

P2860

Optimization of N-aryl-6-methoxy-1,2,3,4-tetrahydroquinolines as tubulin polymerization inhibitors

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2015 nî lūn-bûn

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2015年の論文

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2015年論文

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2015年論文

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2015年論文

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2015年論文

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2015年論文

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2015年论文

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2015年论文

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name

Optimization of N-aryl-6-metho ...... ulin polymerization inhibitors

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Optimization of N-aryl-6-metho ...... ulin polymerization inhibitors

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type

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label

Optimization of N-aryl-6-metho ...... ulin polymerization inhibitors

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Optimization of N-aryl-6-metho ...... ulin polymerization inhibitors

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prefLabel

Optimization of N-aryl-6-metho ...... ulin polymerization inhibitors

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Optimization of N-aryl-6-metho ...... ulin polymerization inhibitors

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P1476

Optimization of N-aryl-6-metho ...... ulin polymerization inhibitors

@en

P2093

Bingjie Qin

http://www.w3.org/2001/XMLSchema#string

Dong-Qing Zhu

http://www.w3.org/2001/XMLSchema#string

Emika Ohkoshi

http://www.w3.org/2001/XMLSchema#string

Ernest Hamel

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Kuo-Hsiung Lee

http://www.w3.org/2001/XMLSchema#string

Lan Xie

http://www.w3.org/2001/XMLSchema#string

Masuo Goto

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Mu-Tian Cui

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Sheng-Biao Wang

http://www.w3.org/2001/XMLSchema#string

Susan L Morris-Natschke

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P2860

Variations in the colchicine-binding domain provide insight into the structural switch of tubulin

Microtubule-binding agents: a dynamic field of cancer therapeutics.

Comparison of in vitro anticancer-drug-screening data generated with a tetrazolium assay versus a protein assay against a diverse panel of human tumor cell lines.

Discovery of 7-hydroxy-6-methoxy-2-methyl-3-(3,4,5-trimethoxybenzoyl)benzo[b]furan (BNC105), a tubulin polymerization inhibitor with potent antiproliferative and tumor vascular disrupting properties.

Lead optimization of dual tubulin and Hsp27 inhibitors

The unique characteristics of tumor vasculature and preclinical evidence for its selective disruption by Tumor-Vascular Disrupting Agents.

A perspective on vascular disrupting agents that interact with tubulin: preclinical tumor imaging and biological assessment

Evaluation of antimitotic agents by quantitative comparisons of their effects on the polymerization of purified tubulin.

Antitumor agents. 293. Nontoxic dimethyl-4,4'-dimethoxy-5,6,5',6'-dimethylenedioxybiphenyl-2,2'-dicarboxylate (DDB) analogues chemosensitize multidrug-resistant cancer cells to clinical anticancer drugs.

Disrupting tumour blood vessels.

P304

5740-5747

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P31

scholarly article

P356

10.1016/J.BMC.2015.07.016

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English

P433

http://www.w3.org/2001/XMLSchema#string

P478

http://www.w3.org/2001/XMLSchema#string

P50

Kan-Yen Hsieh

P577

2015-07-17T00:00:00Z

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P698

26242242

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P932

4554882

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Optimization of N-aryl-6-methoxy-1,2,3,4-tetrahydroquinolines as tubulin polymerization inhibitors

about

P2860

P2860

Optimization of N-aryl-6-methoxy-1,2,3,4-tetrahydroquinolines as tubulin polymerization inhibitors

description

name

type

label

prefLabel

P1433

P1476

P2093

P2860

P304

P31

P356

P407

P433

P478

P50

P577

P698

P932

P356

P1433

P1476

P2093

P2860

P304

P31

P356

P407

P433

P478

P50

P577

P698

P932