The hepatic sinusoid in aging and cirrhosis: effects on hepatic substrate disposition and drug clearance.
about
Pharmacokinetic drug interactions in liver disease: An updateThe Relationship between fenestrations, sieve plates and rafts in liver sinusoidal endothelial cellsHuman hepatic sinusoidal endothelial cells can be distinguished by expression of phenotypic markers related to their specialised functions in vivoThe response of fenestrations, actin, and caveolin-1 to vascular endothelial growth factor in SK Hep1 cells.Three-dimensional structured illumination microscopy of liver sinusoidal endothelial cell fenestrations.Population pharmacokinetic and pharmacodynamic analysis of linezolid and a hematologic side effect, thrombocytopenia, in Japanese patients.Relevance of Liver Failure for Anti-Infective Agents: From Pharmacokinetic Alterations to Dosage AdjustmentsAge-related changes in scavenger receptor-mediated endocytosis in rat liver sinusoidal endothelial cellsLiver immunology.Age-related pseudocapillarization of the liver sinusoidal endothelium impairs the hepatic clearance of acetaminophen in rats.Effects of old age on vascular complexity and dispersion of the hepatic sinusoidal networkLiver sinusoidal endothelial fenestrations in caveolin-1 knockout mice.Age-related changes in the hepatic pharmacology and toxicology of paracetamol.Clinical pharmacology of chemotherapy agents in older people with cancerClinical implications of changes in hepatic drug metabolism in older peopleLoss of PDGF-B activity increases hepatic vascular permeability and enhances insulin sensitivity.Caloric restriction reduces age-related pseudocapillarization of the hepatic sinusoid.Age-related changes in the hepatic microcirculation in miceEvidence of accelerated ageing in clinical drug addiction from immune, hepatic and metabolic biomarkers.Aging and clinical pharmacology: implications for antidepressants.Caloric restriction versus drug therapy to delay the onset of aging diseases and extend life.Clinical pharmacology in the geriatric patient.Age-related changes in the liver sinusoidal endothelium: a mechanism for dyslipidemia.The liver sinusoidal endothelial cell: a cell type of controversial and confusing identity.Ultrastructure of the liver microcirculation influences hepatic and systemic insulin activity and provides a mechanism for age-related insulin resistancePharmacokinetics and drug metabolism in the elderly.The effect of liver disease on inhibitory and plasma protein-binding displacement interactions: an update.Drug metabolism in older people--a key consideration in achieving optimal outcomes with medicines.Anticoagulant therapy with the oral direct factor Xa inhibitors rivaroxaban, apixaban and edoxaban and the thrombin inhibitor dabigatran etexilate in patients with hepatic impairment.Immunobiology of Plasmodium in liver and brain.Approaches for dosage individualisation in critically ill patients.Analgesia for the cirrhotic patient: a literature review and recommendations.A Sieve-Raft Hypothesis for the regulation of endothelial fenestrations.Some considerations on the predictions of pharmacokinetic alterations in subjects with liver disease.Alterations in drug disposition in older adults.Pharmacokinetic variations in cancer patients with liver dysfunction: applications and challenges of pharmacometabolomics.Quantitative and integrative analysis of paracrine hepatocyte activation by nonparenchymal cells upon lipopolysaccharide induction.In-vitro evaluation of chronic alcohol effects on expression of drug-metabolizing and drug-transporting proteins.Pharmacokinetic and pharmacodynamic alterations in older people with dementia.Dietary macronutrients and the aging liver sinusoidal endothelial cell.
P2860
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P2860
The hepatic sinusoid in aging and cirrhosis: effects on hepatic substrate disposition and drug clearance.
description
2005 nî lūn-bûn
@nan
2005年の論文
@ja
2005年論文
@yue
2005年論文
@zh-hant
2005年論文
@zh-hk
2005年論文
@zh-mo
2005年論文
@zh-tw
2005年论文
@wuu
2005年论文
@zh
2005年论文
@zh-cn
name
The hepatic sinusoid in aging ...... isposition and drug clearance.
@ast
The hepatic sinusoid in aging ...... isposition and drug clearance.
@en
type
label
The hepatic sinusoid in aging ...... isposition and drug clearance.
@ast
The hepatic sinusoid in aging ...... isposition and drug clearance.
@en
prefLabel
The hepatic sinusoid in aging ...... isposition and drug clearance.
@ast
The hepatic sinusoid in aging ...... isposition and drug clearance.
@en
P50
P1476
The hepatic sinusoid in aging ...... disposition and drug clearance
@en
P2093
Allan J McLean
Robin Fraser
P304
P356
10.2165/00003088-200544020-00004
P577
2005-01-01T00:00:00Z
P6179
1036669005