Pentosan polysulfate increases affinity between ADAMTS-5 and TIMP-3 through formation of an electrostatically driven trimolecular complex.
about
Pentosan polysulfate: a novel therapy for the mucopolysaccharidosesInjectable and bioresponsive hydrogels for on-demand matrix metalloproteinase inhibitionSulfated glycosaminoglycans control the extracellular trafficking and the activity of the metalloprotease inhibitor TIMP-3.Antibody-based exosite inhibitors of ADAMTS-5 (aggrecanase-2)Systems Based Study of the Therapeutic Potential of Small Charged Molecules for the Inhibition of IL-1 Mediated Cartilage DegradationCell-matrix interactions: focus on proteoglycan-proteinase interplay and pharmacological targeting in cancer.Engineered Tissue Inhibitor of Metalloproteinases-3 Variants Resistant to Endocytosis Have Prolonged Chondroprotective Activity.Low density lipoprotein receptor-related protein 1 (LRP1)-mediated endocytic clearance of a disintegrin and metalloproteinase with thrombospondin motifs-4 (ADAMTS-4): functional differences of non-catalytic domains of ADAMTS-4 and ADAMTS-5 in LRP1 bImproved clinical outcome measures of knee pain and function with concurrent resolution of subchondral Bone Marrow Edema Lesion and joint effusion in an osteoarthritic patient following Pentosan Polysulphate Sodium treatment: a case report.Suramin Inhibits Osteoarthritic Cartilage Degradation by Increasing Extracellular Levels of Chondroprotective Tissue Inhibitor of Metalloproteinases 3.
P2860
Q27319509-2018C49B-D9D5-4ACE-BE1B-9C7958988935Q33650887-00C7CF33-D0D4-4A89-9FCA-9B336A1FA42AQ34410797-6A4325E0-46A2-4BDC-8B39-4A9C1BAC865CQ35754121-4BFA8BFA-064F-481F-9218-1D6FEA0E3317Q36224923-21D17942-7EA7-4732-8360-D500F8FC06A4Q37282934-CE5AD6DF-DBEC-45F7-9E33-10E01ABA6010Q37338894-84B72362-AE87-42C8-92AC-1A86AE4E842DQ37622540-9F9F5B33-71DF-4947-8187-F58963B51E53Q41154182-C66CF590-86A4-4948-BF94-E09391800435Q41642671-BD43CE36-12E4-4584-B482-DEFE93381231
P2860
Pentosan polysulfate increases affinity between ADAMTS-5 and TIMP-3 through formation of an electrostatically driven trimolecular complex.
description
2012 nî lūn-bûn
@nan
2012年の論文
@ja
2012年論文
@yue
2012年論文
@zh-hant
2012年論文
@zh-hk
2012年論文
@zh-mo
2012年論文
@zh-tw
2012年论文
@wuu
2012年论文
@zh
2012年论文
@zh-cn
name
Pentosan polysulfate increases ...... y driven trimolecular complex.
@ast
Pentosan polysulfate increases ...... y driven trimolecular complex.
@en
type
label
Pentosan polysulfate increases ...... y driven trimolecular complex.
@ast
Pentosan polysulfate increases ...... y driven trimolecular complex.
@en
prefLabel
Pentosan polysulfate increases ...... y driven trimolecular complex.
@ast
Pentosan polysulfate increases ...... y driven trimolecular complex.
@en
P2093
P2860
P356
P1433
P1476
Pentosan polysulfate increases ...... y driven trimolecular complex.
@en
P2093
Barbara Mulloy
Gillian Murphy
Hideaki Nagase
Linda Troeberg
Meng-Huee Lee
Peter Ghosh
P2860
P304
P356
10.1042/BJ20112159
P407
P577
2012-04-01T00:00:00Z