Resurgence of serine: an often neglected but indispensable amino Acid
about
Serine, glycine and one-carbon units: cancer metabolism in full circleSerine and glycine metabolism in cancerDietary requirements of synthesizable amino acids by animals: a paradigm shift in protein nutritionPCK2 activation mediates an adaptive response to glucose depletion in lung cancerMitochondrial phosphoenolpyruvate carboxykinase (PEPCK-M) is a pro-survival, endoplasmic reticulum (ER) stress response gene involved in tumor cell adaptation to nutrient availabilityAssessing the carcinogenic potential of low-dose exposures to chemical mixtures in the environment: the challenge aheadKDM4C and ATF4 Cooperate in Transcriptional Control of Amino Acid MetabolismThe intrinsic disorder alphabet. III. Dual personality of serine.Single-cell mass spectrometry reveals small molecules that affect cell fates in the 16-cell embryoMetabolic reprogramming and dysregulated metabolism: cause, consequence and/or enabler of environmental carcinogenesis?Structure of L-serine dehydratase from Legionella pneumophila: novel use of the C-terminal cysteine as an intrinsic competitive inhibitor.Bioinformatics analysis of the serine and glycine pathway in cancer cellsCharacterization of the usage of the serine metabolic network in human cancercMyc-mediated activation of serine biosynthesis pathway is critical for cancer progression under nutrient deprivation conditions.Integrated network analysis and logistic regression modeling identify stage-specific genes in Oral Squamous Cell CarcinomaMitochondrial phosphoenolpyruvate carboxykinase (PEPCK-M) and serine biosynthetic pathway genes are co-ordinately increased during anabolic agent-induced skeletal muscle growth.Role in tumor growth of a glycogen debranching enzyme lost in glycogen storage disease.Novel chemoimmunotherapeutic strategy for hepatocellular carcinoma based on a genome-wide association studyEffect of multi-nutrient insufficiency on markers of one carbon metabolism in young women: response to a methionine load.Dietary essentiality of "nutritionally non-essential amino acids" for animals and humans.Hexokinase 2 is required for tumor initiation and maintenance and its systemic deletion is therapeutic in mouse models of cancer.Brain proteomics supports the role of glutamate metabolism and suggests other metabolic alterations in protein l-isoaspartyl methyltransferase (PIMT)-knockout miceThe histone H3 methyltransferase G9A epigenetically activates the serine-glycine synthesis pathway to sustain cancer cell survival and proliferation.Metabolomic analysis reveals altered metabolic pathways in a rat model of gastric carcinogenesis.Heterogeneity in Cancer Metabolism: New Concepts in an Old Field.Serine biosynthesis by photorespiratory and non-photorespiratory pathways: an interesting interplay with unknown regulatory networks.Phosphoglycerate dehydrogenase: potential therapeutic target and putative metabolic oncogene.Uncovering metabolism in rhabdomyosarcoma.Glutamine at focus: versatile roles in cancer.α-Ketothioamide Derivatives: A Promising Tool to Interrogate Phosphoglycerate Dehydrogenase (PHGDH).PKM2, cancer metabolism, and the road ahead.Antineoplastic activity of strawberry (Fragaria×ananassa Duch.) crude extracts on B16-F10 melanoma cells.Serine starvation induces stress and p53-dependent metabolic remodelling in cancer cells.Mitochondria in endothelial cells: Sensors and integrators of environmental cues.Overexpression of PSP1 enhances growth of transgenic Arabidopsis plants under ambient air conditions.Transcriptional Profiling Reveals a Common Metabolic Program in High-Risk Human Neuroblastoma and Mouse Neuroblastoma Sphere-Forming Cells.Artemether Exhibits Amoebicidal Activity against Acanthamoeba castellanii through Inhibition of the Serine Biosynthesis PathwayIntegration of flux measurements to resolve changes in anabolic and catabolic metabolism in cardiac myocytesDifferences in elongation of very long chain fatty acids and fatty acid metabolism between triple-negative and hormone receptor-positive breast cancer.Neuronal Progenitor Maintenance Requires Lactate Metabolism and PEPCK-M-Directed Cataplerosis.
P2860
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P2860
Resurgence of serine: an often neglected but indispensable amino Acid
description
2012 nî lūn-bûn
@nan
2012年の論文
@ja
2012年学术文章
@wuu
2012年学术文章
@zh-cn
2012年学术文章
@zh-hans
2012年学术文章
@zh-my
2012年学术文章
@zh-sg
2012年學術文章
@yue
2012年學術文章
@zh
2012年學術文章
@zh-hant
name
Resurgence of serine: an often neglected but indispensable amino Acid
@ast
Resurgence of serine: an often neglected but indispensable amino Acid
@en
type
label
Resurgence of serine: an often neglected but indispensable amino Acid
@ast
Resurgence of serine: an often neglected but indispensable amino Acid
@en
prefLabel
Resurgence of serine: an often neglected but indispensable amino Acid
@ast
Resurgence of serine: an often neglected but indispensable amino Acid
@en
P2860
P356
P1476
Resurgence of serine: an often neglected but indispensable amino Acid
@en
P2093
Richard W Hanson
P2860
P304
19786-19791
P356
10.1074/JBC.R112.357194
P407
P577
2012-05-07T00:00:00Z