High-fat feeding promotes obesity via insulin receptor/PI3K-dependent inhibition of SF-1 VMH neurons.
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Ion Channels in Obesity: Pathophysiology and Potential Therapeutic TargetsNeuronal Control of Adaptive ThermogenesisFrom neuroanatomy to behavior: central integration of peripheral signals regulating feeding behaviorNeural Control of Energy ExpenditureLeptin signaling and leptin resistanceSteroidogenic Factor 1 in the Ventromedial Nucleus of the Hypothalamus Regulates Age-Dependent ObesityMutations in a guanylate cyclase GCY-35/GCY-36 modify Bardet-Biedl syndrome-associated phenotypes in Caenorhabditis elegansInsulin in the nervous system and the mind: Functions in metabolism, memory, and moodFOXO1 in the ventromedial hypothalamus regulates energy balanceInsulin resistance in brain alters dopamine turnover and causes behavioral disorders.Central neural regulation of brown adipose tissue thermogenesis and energy expenditureNeuronal control of peripheral insulin sensitivity and glucose metabolismInsulin action in brain regulates systemic metabolism and brain function.Hypothalamic circuits regulating appetite and energy homeostasis: pathways to obesity.Metabolic regulation by protein tyrosine phosphatases.Hypothalamic AMPK-ER Stress-JNK1 Axis Mediates the Central Actions of Thyroid Hormones on Energy Balance.Neonatal insulin action impairs hypothalamic neurocircuit formation in response to maternal high-fat feeding.Ventromedial hypothalamus-specific Ptpn1 deletion exacerbates diet-induced obesity in female mice.The fat mass and obesity associated gene (Fto) regulates activity of the dopaminergic midbrain circuitry.Interleukin-18 null mutation increases weight and food intake and reduces energy expenditure and lipid substrate utilization in high-fat diet fed mice.A parabrachial-hypothalamic cholecystokinin neurocircuit controls counterregulatory responses to hypoglycemiaWired on sugar: the role of the CNS in the regulation of glucose homeostasis.Genetic labeling of steroidogenic factor-1 (SF-1) neurons in mice reveals ventromedial nucleus of the hypothalamus (VMH) circuitry beginning at neurogenesis and development of a separate non-SF-1 neuronal cluster in the ventrolateral VMH.Hypothalamic inflammation: a double-edged sword to nutritional diseases.Transient early food restriction leads to hypothalamic changes in the long-lived crowded litter female mice.Stimulation of the hypothalamic ventromedial nuclei by pituitary adenylate cyclase-activating polypeptide induces hypophagia and thermogenesisCentral nervous system regulation of brown adipose tissue.Central control of brown adipose tissue thermogenesis.IRS2 signaling in LepR-b neurons suppresses FoxO1 to control energy balance independently of leptin action.Sex-dependent changes in metabolism and behavior, as well as reduced anxiety after eliminating ventromedial hypothalamus excitatory output.Nutritional conditions regulate transcriptional activity of SF-1 by controlling sumoylation and ubiquitination.Tub has a key role in insulin and leptin signaling and action in vivo in hypothalamic nucleiCentral regulation of metabolism by protein tyrosine phosphatasesVentromedial hypothalamic expression of Bdnf is required to establish normal patterns of afferent GABAergic connectivity and responses to hypoglycemia.Leptin signaling and circuits in puberty and fertilityWnt3a upregulates brain-derived insulin by increasing NeuroD1 via Wnt/β-catenin signaling in the hypothalamus.Hypothalamic ventromedial COUP-TFII protects against hypoglycemia-associated autonomic failure.Revisiting the Ventral Medial Nucleus of the Hypothalamus: The Roles of SF-1 Neurons in Energy Homeostasis.Attenuation of insulin signalling contributes to FSN-1-mediated regulation of synapse development.Unraveling the Paradox of Selective Insulin Resistance in the Liver: the Brain-Liver Connection
P2860
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P2860
High-fat feeding promotes obesity via insulin receptor/PI3K-dependent inhibition of SF-1 VMH neurons.
description
2011 nî lūn-bûn
@nan
2011年の論文
@ja
2011年論文
@yue
2011年論文
@zh-hant
2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
@zh-tw
2011年论文
@wuu
2011年论文
@zh
2011年论文
@zh-cn
name
High-fat feeding promotes obes ...... nhibition of SF-1 VMH neurons.
@ast
High-fat feeding promotes obes ...... nhibition of SF-1 VMH neurons.
@en
type
label
High-fat feeding promotes obes ...... nhibition of SF-1 VMH neurons.
@ast
High-fat feeding promotes obes ...... nhibition of SF-1 VMH neurons.
@en
prefLabel
High-fat feeding promotes obes ...... nhibition of SF-1 VMH neurons.
@ast
High-fat feeding promotes obes ...... nhibition of SF-1 VMH neurons.
@en
P2093
P2860
P356
P1433
P1476
High-fat feeding promotes obes ...... nhibition of SF-1 VMH neurons.
@en
P2093
Andreas Husch
Bengt F Belgardt
Bradford B Lowell
Brigitte Hampel
Harveen Dhillon
Jeffrey M Zigman
Joel K Elmquist
Jong-Woo Sohn
Lars Paeger
Linda A W Verhagen
P2860
P2888
P304
P356
10.1038/NN.2847
P407
P577
2011-06-05T00:00:00Z
P5875
P6179
1007053573