Coordinated regulation of neuronal mRNA steady-state levels through developmentally controlled intron retention.
about
Dynamic integration of splicing within gene regulatory pathwaysThe long noncoding RNA Pnky regulates neuronal differentiation of embryonic and postnatal neural stem cellsEvolutionary conservation of a molecular machinery for export and expression of mRNAs with retained intronsWidespread intron retention in mammals functionally tunes transcriptomesNOVA-dependent regulation of cryptic NMD exons controls synaptic protein levels after seizure.An NXF1 mRNA with a retained intron is expressed in hippocampal and neocortical neurons and is translated into a protein that functions as an Nxf1 cofactor.Contrasting expression patterns of coding and noncoding parts of the human genome upon oxidative stress.The U6 snRNA m6A Methyltransferase METTL16 Regulates SAM Synthetase Intron Retention.Spliceosomal protein eftud2 mutation leads to p53-dependent apoptosis in zebrafish neural progenitors.An Ultraconserved Element (UCE) controls homeostatic splicing of ARGLU1 mRNA.Origin of spliceosomal introns and alternative splicingIntron retention is regulated by altered MeCP2-mediated splicing factor recruitment.Quantitative analysis of cryptic splicing associated with TDP-43 depletion.Genome annotation for clinical genomic diagnostics: strengths and weaknessesTranscriptome analysis of human tissues and cell lines reveals one dominant transcript per geneA novel functional role for MMSET in RNA processing based on the link between the REIIBP isoform and its interaction with the SMN complexAlternative splicing shapes transcriptome but not proteome diversity in Physcomitrella patens.Concordance of deregulated mechanisms unveiled in underpowered experiments: PTBP1 knockdown case studyMicroRNA miR-124 controls the choice between neuronal and astrocyte differentiation by fine-tuning Ezh2 expressionCharacterization of a novel posttranslational modification in polypyrimidine tract-binding proteins by SUMO1.Regulation of mRNA trafficking by nuclear pore complexes.Regulation of mRNA abundance by polypyrimidine tract-binding protein-controlled alternate 5' splice site choiceUnmasking alternative splicing inside protein-coding exons defines exitrons and their role in proteome plasticity.Detained introns are a novel, widespread class of post-transcriptionally spliced introns.Drosophila Hephaestus/polypyrimidine tract binding protein is required for dorso-ventral patterning and regulation of signalling between the germline and soma.A posttranscriptional mechanism that controls Ptbp1 abundance in the Xenopus epidermisMicroRNA-mediated repression of nonsense mRNAs.BS69/ZMYND11 reads and connects histone H3.3 lysine 36 trimethylation-decorated chromatin to regulated pre-mRNA processingNeural differentiation modulates the vertebrate brain specific splicing programHistone H3.3 and cancer: A potential reader connection.Canonical Poly(A) Polymerase Activity Promotes the Decay of a Wide Variety of Mammalian Nuclear RNAs.A post-transcriptional mechanism pacing expression of neural genes with precursor cell differentiation status.Uncovering the roles of long noncoding RNAs in neural development and glioma progressionNon-coding functions of alternative pre-mRNA splicing in development.Alternative exon definition events control the choice between nuclear retention and cytoplasmic export of U11/U12-65K mRNA.Regulation of mRNA Levels by Decay-Promoting Introns that Recruit the Exosome Specificity Factor Mmi1.A dynamic intron retention program enriched in RNA processing genes regulates gene expression during terminal erythropoiesis.The splicing regulator PTBP1 controls the activity of the transcription factor Pbx1 during neuronal differentiation.Hyper conserved elements in vertebrate mRNA 3'-UTRs reveal a translational network of RNA-binding proteins controlled by HuR.A dynamic intron retention program in the mammalian megakaryocyte and erythrocyte lineages
P2860
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P2860
Coordinated regulation of neuronal mRNA steady-state levels through developmentally controlled intron retention.
description
2012 nî lūn-bûn
@nan
2012年の論文
@ja
2012年論文
@yue
2012年論文
@zh-hant
2012年論文
@zh-hk
2012年論文
@zh-mo
2012年論文
@zh-tw
2012年论文
@wuu
2012年论文
@zh
2012年论文
@zh-cn
name
Coordinated regulation of neur ...... y controlled intron retention.
@ast
Coordinated regulation of neur ...... y controlled intron retention.
@en
type
label
Coordinated regulation of neur ...... y controlled intron retention.
@ast
Coordinated regulation of neur ...... y controlled intron retention.
@en
prefLabel
Coordinated regulation of neur ...... y controlled intron retention.
@ast
Coordinated regulation of neur ...... y controlled intron retention.
@en
P2093
P2860
P356
P1433
P1476
Coordinated regulation of neur ...... y controlled intron retention.
@en
P2093
Piyush Khandelia
Zhao Qin Lim
P2860
P304
P356
10.1101/GAD.188037.112
P577
2012-06-01T00:00:00Z