Activation of Indian hedgehog promotes chondrocyte hypertrophy and upregulation of MMP-13 in human osteoarthritic cartilage
about
Epigenetic regulation in chondrocyte phenotype maintenance for cell-based cartilage repairPathophysiology of osteoarthritis: canonical NF-κB/IKKβ-dependent and kinase-independent effects of IKKα in cartilage degradation and chondrocyte differentiationEndoplasmic Reticulum Stress and Unfolded Protein Response in Cartilage Pathophysiology; Contributing Factors to Apoptosis and Osteoarthritis.Effects of doxycycline on mesenchymal stem cell chondrogenesis and cartilage repair.Indian hedgehog in synovial fluid is a novel marker for early cartilage lesions in human knee joint.Signaling pathways in cartilage repair.CCAAT/enhancer binding protein β regulates expression of Indian hedgehog during chondrocytes differentiation.MicroRNA-1 regulates chondrocyte phenotype by repressing histone deacetylase 4 during growth plate development.Total-body irradiation produces late degenerative joint damage in ratsIdentification of α2-macroglobulin as a master inhibitor of cartilage-degrading factors that attenuates the progression of posttraumatic osteoarthritisDecreased histone deacetylase 4 is associated with human osteoarthritis cartilage degeneration by releasing histone deacetylase 4 inhibition of runt-related transcription factor-2 and increasing osteoarthritis-related genes: a novel mechanism of humExpression of hedgehog signal pathway in articular cartilage is associated with the severity of cartilage damage in rats with adjuvant-induced arthritis.Indian Hedgehog signaling pathway members are associated with magnetic resonance imaging manifestations and pathological scores in lumbar facet joint osteoarthritisMicroRNA-602 and microRNA-608 regulate sonic hedgehog expression via target sites in the coding region in human chondrocytesIdentification of α1-Antitrypsin as a Potential Candidate for Internal Control for Human Synovial Fluid in Western Blot.Hedgehog signalling does not stimulate cartilage catabolism and is inhibited by Interleukin-1βResponse of knee fibrocartilage to joint destabilization.Abnormal Mechanical Loading Induces Cartilage Degeneration by Accelerating Meniscus Hypertrophy and Mineralization After ACL Injuries In Vivo.Endochondral Growth Defect and Deployment of Transient Chondrocyte Behaviors Underlie Osteoarthritis Onset in a Natural Murine ModelIntra-Articular Injection of Cross-Linked Hyaluronic Acid-Dexamethasone Hydrogel Attenuates Osteoarthritis: An Experimental Study in a Rat Model of Osteoarthritis.Correlation between Gene Expression and Osteoarthritis Progression in Human.Disrupting the Indian hedgehog signaling pathway in vivo attenuates surgically induced osteoarthritis progression in Col2a1-CreERT2; Ihhfl/fl mice.Wnt and Rho GTPase signaling in osteoarthritis development and intervention: implications for diagnosis and therapy.Osteoarthritis year in review 2013: biology.Indian Hedgehog, a critical modulator in osteoarthritis, could be a potential therapeutic target for attenuating cartilage degeneration disease.IFT88 influences chondrocyte actin organization and biomechanics.Knockdown of PRMT1 suppresses IL-1β-induced cartilage degradation and inflammatory responses in human chondrocytes through Gli1-mediated Hedgehog signaling pathway.Primary cilia disassembly down-regulates mechanosensitive hedgehog signalling: a feedback mechanism controlling ADAMTS-5 expression in chondrocytes.Recent advances in the understanding of molecular mechanisms of cartilage degeneration, synovitis and subchondral bone changes in osteoarthritis.Emerging potential of gene silencing approaches targeting anti-chondrogenic factors for cell-based cartilage repair.Inhibition of Notch1 promotes hedgehog signalling in a HES1-dependent manner in chondrocytes and exacerbates experimental osteoarthritis.Reduced primary cilia length and altered Arl13b expression are associated with deregulated chondrocyte Hedgehog signaling in alkaptonuria.Targeted designed variants of alpha-2-macroglobulin (A2M) attenuate cartilage degeneration in a rat model of osteoarthritis induced by anterior cruciate ligament transection.Study of chondrogenic potential of stem cells in co-culture with chondrons.Hypoxia promotes the production and inhibits the destruction of human articular cartilage.Biological effects and osteoarthritic disease-modifying activity of small molecule CM-01.Expression of the deubiquitinase cylindromatosis in articular cartilage and subchondral bone is associated with the severity of knee osteoarthritis.Smoothened-antagonists reverse homogentisic acid-induced alterations of Hedgehog signaling and primary cilium length in alkaptonuria.A novel therapeutic strategy for cartilage diseases based on lipid nanoparticle-RNAi delivery system.Hedgehog signal expression in articular cartilage of rat temporomandibular joint and association with adjuvant-induced osteoarthritis.
P2860
Q26775032-041CF2A1-2177-4ACC-9EB6-5B188AABE933Q26777901-CFD329E9-688B-4C75-AC41-130A63F9FE10Q30235128-E28086D5-124E-4AB9-BAD3-FEEC40952080Q33574124-29A90305-94DD-4C20-9027-39385A7B4AB1Q33755536-CDDCDB9C-0A61-4596-B3D9-8955C3C1E328Q33755839-59B9BFA7-9C30-47C9-8E86-58105213A652Q34020416-F7E8EDD9-9FAA-4612-98DA-0710D42AC0FDQ34072681-2CB74DA6-29AE-43E0-A5FF-1014DF14A800Q34175120-434C9AFE-BA75-4012-A74E-C22E5DF6FA33Q34296547-3355B5BD-2D02-4DC4-9425-BE8650BED76FQ34695447-EBEC62CA-EF4B-4F16-B5AA-124E5B36E92BQ35226203-9917D89F-ED14-4547-81E9-CC6A8F249B7BQ35627642-EB6B2C59-6625-448D-90BE-593B169DC426Q35962544-01DB8200-268C-4F89-8686-1F16715E01B2Q36292289-AA860237-D71C-4924-BA8E-D20B15B16B8AQ36477430-C5F5B3C1-CFDE-4987-8031-EC06E8DC6DC7Q36591441-F08F2267-D85C-4D76-9D5A-7A60FBA155DAQ36642390-387C843B-43D4-4ACE-845D-2871FE493E9EQ36800126-046B47D7-AB33-499D-9EF3-131DABD9B093Q36846838-ED503113-27CB-4199-BA59-DB4FC355895BQ37134637-2CF2436F-8DFB-48F3-B2C8-2FA48BC95759Q37689672-6B0B7A3D-CA79-475E-AE8D-3F6C83499086Q37691249-1DD5C4FB-6105-4DF5-B672-0CDB27A703FCQ38115104-CEC705CD-59D7-4EC2-AA6F-F7ADD3DAA5C0Q38213112-B3D2B634-C1CA-4B6E-AA20-D36824D96CD1Q38652731-C394B103-B788-4291-A0BB-0C9A3942CA13Q38661033-481A7EEE-EB95-41D0-A535-5216FB2C820CQ38788566-885734CD-FDD2-4CC2-B0A2-B2D9FAD320DDQ38861162-D2F7BF3F-4CA1-4D66-ACE3-0DD8DD11C52AQ39256778-578C18BC-1A62-4AB3-845F-57ACDED44F08Q40018531-0A949436-D71C-4A56-A7C5-511F24C1B826Q41040305-DA9ECD37-AD2A-4E7F-980A-0F58AE0250BAQ41117345-AC8D1EF4-F4E1-41A4-A3CA-DECD6550E71FQ42260549-00E39B6B-B706-4BFD-BA3F-14D2442A46F1Q43491158-708A1CAB-F71F-4BE2-A050-4E33A0BDF9EAQ46145410-13A54C56-2535-4D48-A2C4-9E2F60A282A8Q47166364-9309CBDC-CCDA-480D-AD07-B959AD569180Q48117931-8AFDAD43-3C24-4348-B75F-EF89CDC28F8EQ49378127-31CAEA03-96ED-46A3-9649-279361ADE3CEQ50197131-67075C83-2BBF-4BEA-B049-8CFD7A26DDEF
P2860
Activation of Indian hedgehog promotes chondrocyte hypertrophy and upregulation of MMP-13 in human osteoarthritic cartilage
description
2012 nî lūn-bûn
@nan
2012年の論文
@ja
2012年論文
@yue
2012年論文
@zh-hant
2012年論文
@zh-hk
2012年論文
@zh-mo
2012年論文
@zh-tw
2012年论文
@wuu
2012年论文
@zh
2012年论文
@zh-cn
name
Activation of Indian hedgehog ...... human osteoarthritic cartilage
@ast
Activation of Indian hedgehog ...... human osteoarthritic cartilage
@en
type
label
Activation of Indian hedgehog ...... human osteoarthritic cartilage
@ast
Activation of Indian hedgehog ...... human osteoarthritic cartilage
@en
prefLabel
Activation of Indian hedgehog ...... human osteoarthritic cartilage
@ast
Activation of Indian hedgehog ...... human osteoarthritic cartilage
@en
P2093
P2860
P921
P1476
Activation of Indian hedgehog ...... human osteoarthritic cartilage
@en
P2093
B C Fleming
P2860
P304
P356
10.1016/J.JOCA.2012.03.010
P50
P577
2012-03-30T00:00:00Z