HDAC5 is required for maintenance of pericentric heterochromatin, and controls cell-cycle progression and survival of human cancer cells.
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The anti-tumor effect of HDAC inhibition in a human pancreas cancer model is significantly improved by the simultaneous inhibition of cyclooxygenase 2CDK2-dependent phosphorylation of Suv39H1 is involved in control of heterochromatin replication during cell cycle progressionHistone deacetylases and cancer.The duration of gastrin treatment affects global gene expression and molecular responses involved in ER stress and anti-apoptosis.HDAC Family Members Intertwined in the Regulation of Autophagy: A Druggable Vulnerability in Aggressive Tumor Entities.Histone deacetylases: a saga of perturbed acetylation homeostasis in cancer.HDAC5, a potential therapeutic target and prognostic biomarker, promotes proliferation, invasion and migration in human breast cancer.Towards selective inhibition of histone deacetylase isoforms: what has been achieved, where we are and what will be next.Metal-dependent Deacetylases: Cancer and Epigenetic RegulatorsMyoferlin plays a key role in VEGFA secretion and impacts tumor-associated angiogenesis in human pancreas cancer.Formononetin sensitizes glioma cells to doxorubicin through preventing EMT via inhibition of histone deacetylase 5.Stat3 inhibits PTPN13 expression in squamous cell lung carcinoma through recruitment of HDAC5.Down-regulation of HDAC5 inhibits growth of human hepatocellular carcinoma by induction of apoptosis and cell cycle arrest.Metabolic inhibitors accentuate the anti-tumoral effect of HDAC5 inhibition.Hyper-acetylation contributes to the sensitivity of chemo-resistant prostate cancer cells to histone deacetylase inhibitor Trichostatin A.Myoferlin controls mitochondrial structure and activity in pancreatic ductal adenocarcinoma, and affects tumor aggressiveness.
P2860
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P2860
HDAC5 is required for maintenance of pericentric heterochromatin, and controls cell-cycle progression and survival of human cancer cells.
description
2012 nî lūn-bûn
@nan
2012年の論文
@ja
2012年論文
@yue
2012年論文
@zh-hant
2012年論文
@zh-hk
2012年論文
@zh-mo
2012年論文
@zh-tw
2012年论文
@wuu
2012年论文
@zh
2012年论文
@zh-cn
name
HDAC5 is required for maintena ...... urvival of human cancer cells.
@ast
HDAC5 is required for maintena ...... urvival of human cancer cells.
@en
type
label
HDAC5 is required for maintena ...... urvival of human cancer cells.
@ast
HDAC5 is required for maintena ...... urvival of human cancer cells.
@en
prefLabel
HDAC5 is required for maintena ...... urvival of human cancer cells.
@ast
HDAC5 is required for maintena ...... urvival of human cancer cells.
@en
P2093
P2860
P356
P1476
HDAC5 is required for maintena ...... survival of human cancer cells
@en
P2093
A Gonzalez
F Dequiedt
V Castronovo
P2860
P2888
P304
P356
10.1038/CDD.2012.3
P577
2012-02-03T00:00:00Z