Interaction between genetic and epigenetic variation defines gene expression patterns at the asthma-associated locus 17q12-q21 in lymphoblastoid cell lines
about
Epigenomics and allergic diseaseIntegrative modeling of multiple genomic data from different types of genetic association studies.Integrative modeling of multi-platform genomic data under the framework of mediation analysis.iGWAS: Integrative Genome-Wide Association Studies of Genetic and Genomic Data for Disease Susceptibility Using Mediation Analysis.Epigenetic mechanisms and models in the origins of asthma.Risk of childhood asthma is associated with CpG-site polymorphisms, regional DNA methylation and mRNA levels at the GSDMB/ORMDL3 locusAssociation of childhood chronic physical aggression with a DNA methylation signature in adult human T cells.Allelic expression of deleterious protein-coding variants across human tissues.Aberrant ORM (yeast)-like protein isoform 3 (ORMDL3) expression dysregulates ceramide homeostasis in cells and ceramide exacerbates allergic asthma in miceLymphocyte Activation Dynamics Is Shaped by Hereditary Components at Chromosome Region 17q12-q21Role of DNA methylation in expression control of the IKZF3-GSDMA region in human epithelial cells.Epigenetic mechanisms and the development of asthma.The interaction of genetic variants and DNA methylation of the interleukin-4 receptor gene increase the risk of asthma at age 18 years.Where genotype is not predictive of phenotype: towards an understanding of the molecular basis of reduced penetrance in human inherited disease.The splice site variant rs11078928 may be associated with a genotype-dependent alteration in expression of GSDMB transcripts.DNA methylation and childhood maltreatment: from animal models to human studies.Local genotype influences DNA methylation at two asthma-associated regions, 5q31 and 17q21, in a founder effect population.A meta-analysis of genome-wide association studies of asthma in Puerto Ricans.GWAS in childhood acute lymphoblastic leukemia reveals novel genetic associations at chromosomes 17q12 and 8q24.21.X chromosome dosage and presence of SRY shape sex-specific differences in DNA methylation at an autosomal region in human cells.Lessons from ten years of genome-wide association studies of asthma.A decade of research on the 17q12-21 asthma locus: Piecing together the puzzle.Sex- and age-dependent DNA methylation at the 17q12-q21 locus associated with childhood asthma.
P2860
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P2860
Interaction between genetic and epigenetic variation defines gene expression patterns at the asthma-associated locus 17q12-q21 in lymphoblastoid cell lines
description
2012 nî lūn-bûn
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2012年の論文
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2012年論文
@yue
2012年論文
@zh-hant
2012年論文
@zh-hk
2012年論文
@zh-mo
2012年論文
@zh-tw
2012年论文
@wuu
2012年论文
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name
Interaction between genetic an ...... 1 in lymphoblastoid cell lines
@ast
Interaction between genetic an ...... 1 in lymphoblastoid cell lines
@en
type
label
Interaction between genetic an ...... 1 in lymphoblastoid cell lines
@ast
Interaction between genetic an ...... 1 in lymphoblastoid cell lines
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prefLabel
Interaction between genetic an ...... 1 in lymphoblastoid cell lines
@ast
Interaction between genetic an ...... 1 in lymphoblastoid cell lines
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P2093
P2860
P1433
P1476
Interaction between genetic an ...... 1 in lymphoblastoid cell lines
@en
P2093
Abeer Al Tuwaijri
Dominique J Verlaan
Manon Ouimet
Sanny Moussette
Soizik Berlivet
Tomi Pastinen
Vonda Koka
P2860
P2888
P304
P356
10.1007/S00439-012-1142-X
P577
2012-01-24T00:00:00Z