Striatal-enriched protein-tyrosine phosphatase (STEP) regulates Pyk2 kinase activity. - Wikidata - awgldk - TriplyDB

Striatal-enriched protein-tyrosine phosphatase (STEP) regulates Pyk2 kinase activity.

Striatal-enriched protein-tyrosine phosphatase (STEP) regulates Pyk2 kinase activity.

http://www.wikidata.org/entity/Q36033151

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Role of Striatal-Enriched Tyrosine Phosphatase in Neuronal Function Inhibition of the tyrosine phosphatase STEP61 restores BDNF expression and reverses motor and cognitive deficits in phencyclidine-treated mice.Striatal-enriched protein tyrosine phosphatase in Alzheimer's disease.STEP61 is a substrate of the E3 ligase parkin and is upregulated in Parkinson's disease The tyrosine phosphatase STEP: implications in schizophrenia and the molecular mechanism underlying antipsychotic medications Striatal-enriched protein tyrosine phosphatase-STEPs toward understanding chronic stress-induced activation of corticotrophin releasing factor neurons in the rat bed nucleus of the stria terminalis.Neuroprotective role of a brain-enriched tyrosine phosphatase, STEP, in focal cerebral ischemia Inhibition of striatal-enriched tyrosine phosphatase 61 in the dorsomedial striatum is sufficient to increased ethanol consumption Inhibitor of the tyrosine phosphatase STEP reverses cognitive deficits in a mouse model of Alzheimer's disease Computational identification of potential multitarget treatments for ameliorating the adverse effects of amyloid-β on synaptic plasticity Alterations in STriatal-Enriched protein tyrosine Phosphatase expression, activation, and downstream signaling in early and late stages of the YAC128 Huntington's disease mouse model.Substrate-based fragment identification for the development of selective, nonpeptidic inhibitors of striatal-enriched protein tyrosine phosphatase.Disruption of striatal-enriched protein tyrosine phosphatase (STEP) function in neuropsychiatric disorders Striatal-enriched protein tyrosine phosphatase regulates the PTPα/Fyn signaling pathway The DAO gene is associated with schizophrenia and interacts with other genes in the Taiwan Han Chinese population.BDNF Induces Striatal-Enriched Protein Tyrosine Phosphatase 61 Degradation Through the Proteasome.Down-regulation of BDNF in cell and animal models increases striatal-enriched protein tyrosine phosphatase 61 (STEP61 ) levels.The tyrosine phosphatase STEP constrains amygdala-dependent memory formation and neuroplasticity.STEP activation by Gαq coupled GPCRs opposes Src regulation of NMDA receptors containing the GluN2A subunit.Molecular mechanism of ERK dephosphorylation by striatal-enriched protein tyrosine phosphatase.A common STEP in the synaptic pathology of diverse neuropsychiatric disorders.A Human Tyrosine Phosphatase Interactome Mapped by Proteomic Profiling Pyk2 modulates hippocampal excitatory synapses and contributes to cognitive deficits in a Huntington's disease model.Non-receptor-tyrosine kinases integrate fast glucocorticoid signaling in hippocampal neurons.Molecular underpinnings of neurodegenerative disorders: striatal-enriched protein tyrosine phosphatase signaling and synaptic plasticity.Glutathione-Responsive Selenosulfide Prodrugs as a Platform Strategy for Potent and Selective Mechanism-Based Inhibition of Protein Tyrosine Phosphatases.X-ray Characterization and Structure-Based Optimization of Striatal-Enriched Protein Tyrosine Phosphatase Inhibitors.Behavioral characterization of striatal-enriched protein tyrosine phosphatase (STEP) knockout mice.A peptide mimetic of tyrosine phosphatase STEP as a potential therapeutic agent for treatment of cerebral ischemic stroke.NMDA glutamate receptor NR1, NR2A and NR2B expression and NR2B Tyr-1472 phosphorylation in the lens.Synaptic NMDA Receptor Activation Induces Ubiquitination and Degradation of STEP61.The Tyrosine Phosphatase STEP Is Involved in Age-Related Memory Decline.Linkage analysis of multiplex Caribbean Hispanic families loaded for unexplained early-onset cases identifies novel Alzheimer's disease loci Activation of Phosphotyrosine-Mediated Signaling Pathways in the Cortex and Spinal Cord of SOD1, a Mouse Model of Familial Amyotrophic Lateral Sclerosis

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Striatal-enriched protein-tyrosine phosphatase (STEP) regulates Pyk2 kinase activity.

http://www.wikidata.org/entity/Q36033151

description

2012 nî lūn-bûn

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2012年の論文

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2012年論文

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2012年論文

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2012年論文

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2012年論文

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2012年論文

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2012年论文

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2012年论文

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2012年论文

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name

Striatal-enriched protein-tyrosine phosphatase (STEP) regulates Pyk2 kinase activity.

@ast

Striatal-enriched protein-tyrosine phosphatase (STEP) regulates Pyk2 kinase activity.

@en

type

label

Striatal-enriched protein-tyrosine phosphatase (STEP) regulates Pyk2 kinase activity.

@ast

Striatal-enriched protein-tyrosine phosphatase (STEP) regulates Pyk2 kinase activity.

@en

prefLabel

Striatal-enriched protein-tyrosine phosphatase (STEP) regulates Pyk2 kinase activity.

@ast

Striatal-enriched protein-tyrosine phosphatase (STEP) regulates Pyk2 kinase activity.

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Journal of Biological Chemistry

P1476

Striatal-enriched protein-tyrosine phosphatase (STEP) regulates Pyk2 kinase activity

@en

P2093

Jian Xu

http://www.w3.org/2001/XMLSchema#string

Johannes W Hell

http://www.w3.org/2001/XMLSchema#string

Paul J Lombroso

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Pradeep Kurup

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Tommaso Patriarchi

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P2860

Negative regulation of PYK2/related adhesion focal tyrosine kinase signal transduction by hematopoietic tyrosine phosphatase SHPTP1

Selectivity and promiscuity of the first and second PDZ domains of PSD-95 and synapse-associated protein 102

Protein tyrosine kinase PYK2 involved in Ca(2+)-induced regulation of ion channel and MAP kinase functions

A role for Pyk2 and Src in linking G-protein-coupled receptors with MAP kinase activation

PTP-SL and STEP protein tyrosine phosphatases regulate the activation of the extracellular signal-regulated kinases ERK1 and ERK2 by association through a kinase interaction motif.

Interferon-gamma-dependent tyrosine phosphorylation of MEKK4 via Pyk2 is regulated by annexin II and SHP2 in keratinocytes

Identification of a new Pyk2 target protein with Arf-GAP activity

Molecular characterization of a protein-tyrosine-phosphatase enriched in striatum

Tyrosine phosphorylation of Pyk2 is selectively regulated by Fyn during TCR signaling

Genetic reduction of striatal-enriched tyrosine phosphatase (STEP) reverses cognitive and cellular deficits in an Alzheimer's disease mouse model

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corpus striatum

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