The Rd8 mutation of the Crb1 gene is present in vendor lines of C57BL/6N mice and embryonic stem cells, and confounds ocular induced mutant phenotypes.
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APLP2 Regulates Refractive Error and Myopia Development in Mice and HumansShow and tell: disclosure and data sharing in experimental pathologyBirdshot chorioretinopathy: current knowledge and new concepts in pathophysiology, diagnosis, monitoring and treatmentInflammation and its role in age-related macular degenerationMechanisms of age-related macular degenerationAnimal models of age related macular degenerationTyro3 Modulates Mertk-Associated Retinal DegenerationMicrotubule motors transport phagosomes in the RPE, and lack of KLC1 leads to AMD-like pathogenesis.The BALB/c mouse: Effect of standard vivarium lighting on retinal pathology during aging.Dynamic increase in extracellular ATP accelerates photoreceptor cell apoptosis via ligation of P2RX7 in subretinal hemorrhageLack of involvement of CEP adducts in TLR activation and in angiogenesisRPE necroptosis in response to oxidative stress and in AMDArginine deprivation and immune suppression in a mouse model of Alzheimer's diseaseBcl-xL-mediated remodeling of rod and cone synaptic mitochondria after postnatal lead exposure: electron microscopy, tomography and oxygen consumptionIncreased proliferation of late-born retinal progenitor cells by gestational lead exposure delays rod and bipolar cell differentiationIntravitreal administration of HA-1077, a ROCK inhibitor, improves retinal function in a mouse model of huntington diseaseDeletion of PDZD7 disrupts the Usher syndrome type 2 protein complex in cochlear hair cells and causes hearing loss in mice.Animals deficient in C2Orf71, an autosomal recessive retinitis pigmentosa-associated locus, develop severe early-onset retinal degenerationDisruption of the retinitis pigmentosa 28 gene Fam161a in mice affects photoreceptor ciliary structure and leads to progressive retinal degenerationHistopathology reveals correlative and unique phenotypes in a high-throughput mouse phenotyping screenLarge-scale phenotyping of an accurate genetic mouse model of JNCL identifies novel early pathology outside the central nervous systemGenetic background influences age-related decline in visual and nonvisual retinal responses, circadian rhythms, and sleep.A comparative phenotypic and genomic analysis of C57BL/6J and C57BL/6N mouse strains.Methodologies for analysis of patterning in the mouse RPE sheet.Rapid Knockout and Reporter Mouse Line Generation and Breeding Colony Establishment Using EUCOMM Conditional-Ready Embryonic Stem Cells: A Case StudyThe severity of retinal pathology in homozygous Crb1rd8/rd8 mice is dependent on additional genetic factors.In vivo multi-modal imaging of experimental autoimmune uveoretinitis in transgenic reporter mice reveals the dynamic nature of inflammatory changes during disease progression.Gene therapy restores vision in rd1 mice after removal of a confounding mutation in Gpr179Circadian and noncircadian modulation of autophagy in photoreceptors and retinal pigment epithelium.Platelet-derived growth factor (PDGF)-C inhibits neuroretinal apoptosis in a murine model of focal retinal degeneration.Cav1.4 IT mouse as model for vision impairment in human congenital stationary night blindness type 2.Mild reproductive impact of a Y chromosome deletion on a C57BL/6J substrainImmune responses in age-related macular degeneration and a possible long-term therapeutic strategy for preventionSearching for biomarkers of CDKL5 disorder: early-onset visual impairment in CDKL5 mutant mice.Mitochondrial hydrogen peroxide and defective cholesterol efflux prevent in vitro fertilization by cryopreserved inbred mouse sperm.Photoreceptor oxidative stress in hyperoxia-induced proliferative retinopathy accelerates rd8 degenerationThe Na+/Ca2+, K+ exchanger NCKX4 is required for efficient cone-mediated visionParallel universes of Black Six biology.Transcription coactivators p300 and CBP are necessary for photoreceptor-specific chromatin organization and gene expression.mNos2 deletion and human NOS2 replacement in Alzheimer disease models
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P2860
The Rd8 mutation of the Crb1 gene is present in vendor lines of C57BL/6N mice and embryonic stem cells, and confounds ocular induced mutant phenotypes.
description
2012 nî lūn-bûn
@nan
2012年の論文
@ja
2012年論文
@yue
2012年論文
@zh-hant
2012年論文
@zh-hk
2012年論文
@zh-mo
2012年論文
@zh-tw
2012年论文
@wuu
2012年论文
@zh
2012年论文
@zh-cn
name
The Rd8 mutation of the Crb1 g ...... lar induced mutant phenotypes.
@ast
The Rd8 mutation of the Crb1 g ...... lar induced mutant phenotypes.
@en
type
label
The Rd8 mutation of the Crb1 g ...... lar induced mutant phenotypes.
@ast
The Rd8 mutation of the Crb1 g ...... lar induced mutant phenotypes.
@en
prefLabel
The Rd8 mutation of the Crb1 g ...... lar induced mutant phenotypes.
@ast
The Rd8 mutation of the Crb1 g ...... lar induced mutant phenotypes.
@en
P2093
P2860
P356
P1476
The Rd8 mutation of the Crb1 g ...... lar induced mutant phenotypes.
@en
P2093
Eric F Wawrousek
Jayeeta Roychoudhury
Mary J Mattapallil
Thomas A Ferguson
P2860
P304
P356
10.1167/IOVS.12-9662
P407
P577
2012-05-17T00:00:00Z