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Elevated intracellular calcium stimulates NHE3 activity by an IKEPP (NHERF4) dependent mechanismIRBIT, inositol 1,4,5-triphosphate (IP3) receptor-binding protein released with IP3, binds Na+/H+ exchanger NHE3 and activates NHE3 activity in response to calciumMutations in SPINT2 cause a syndromic form of congenital sodium diarrheaNa(+)/H(+) exchanger 1 directly binds to calcineurin A and activates downstream NFAT signaling, leading to cardiomyocyte hypertrophyNHE8 plays important roles in gastric mucosal protectionSp1 and Sp3 control constitutive expression of the human NHE2 promoter by interactions with the proximal promoter and the transcription initiation siteIntestinal secretory mechanisms in irritable bowel syndrome-diarrheaThe yeast endosomal Na+K+/H+ exchanger Nhx1 regulates cellular pH to control vesicle traffickingMolecular cloning and promoter analysis of downregulated in adenoma (DRA)Shank2 associates with and regulates Na+/H+ exchanger 3Na+/H+ Exchangers in Renal Regulation of Acid-Base BalanceLysophosphatidic acid 5 receptor induces activation of Na(+)/H(+) exchanger 3 via apical epidermal growth factor receptor in intestinal epithelial cellsNovel phorbol ester-binding motif mediates hormonal activation of Na+/H+ exchanger.Subcloning, localization, and expression of the rat intestinal sodium-hydrogen exchanger isoform 8.Angiotensin II directly regulates intestinal epithelial NHE3 in Caco2BBE cells.Loss of SLC9A3 decreases CFTR protein and causes obstructed azoospermia in mice.Light-dependent expression of a Na+/H+ exchanger 3-like transporter in the ctenidium of the giant clam, Tridacna squamosa, can be related to increased H+ excretion during light-enhanced calcificationCoordinate down-regulation of adenylyl cyclase isoforms and the stimulatory G protein (G(s)) in intestinal epithelial cell differentiation.PLC-γ directly binds activated c-Src, which is necessary for carbachol-mediated inhibition of NHE3 activity in Caco-2/BBe cellsGlucocorticoids acutely increase cell surface Na+/H+ exchanger-3 (NHE3) by activation of NHE3 exocytosis.A phase 1 study of the safety, tolerability, pharmacodynamics, and pharmacokinetics of tenapanor in healthy Japanese volunteers.The switch of intestinal Slc26 exchangers from anion absorptive to HCOFormula secretory mode is dependent on CFTR anion channel function.Hydrostatic intestinal edema induced signaling pathways: potential role of mechanical forces.Nucleotide sequence of the Na+/H+ exchanger-8 in patients with congenital sodium diarrhea.Functional vacuolar ATPase (V-ATPase) proton pumps traffic to the enterocyte brush border membrane and require CFTR.Epidermal growth factor inhibits intestinal NHE8 expression via reducing its basal transcription.The Na+/H+ exchanger controls deoxycholic acid-induced apoptosis by a H+-activated, Na+-dependent ionic shift in esophageal cellsMorphology and putative function of the colon and cloaca of marine and freshwater snakes.Responses of sodium-hydrogen exchange to nitric oxide in porcine cultured nonpigmented ciliary epitheliumTransepithelial glucose transport and Na+/K+ homeostasis in enterocytes: an integrative model.Sodium hydrogen exchanger as a mediator of hydrostatic edema-induced intestinal contractile dysfunction.Transcriptional inhibition of intestinal NHE8 expression by glucocorticoids involves Pax5.NHE3 activity is dependent on direct phosphoinositide binding at the N terminus of its intracellular cytosolic region.Lysophosphatidic acid stimulates the intestinal brush border Na(+)/H(+) exchanger 3 and fluid absorption via LPA(5) and NHERF2.Downregulation of the NHE3-binding PDZ-adaptor protein PDZK1 expression during cytokine-induced inflammation in interleukin-10-deficient mice.Intestinal inhibition of the Na+/H+ exchanger 3 prevents cardiorenal damage in rats and inhibits Na+ uptake in humans.The enteropathogenic Escherichia coli type III secretion system effector Map binds EBP50/NHERF1: implication for cell signalling and diarrhoea.Endogenous and exogenous control of gastrointestinal epithelial function: building on the legacy of Bayliss and Starling.Somatostatin stimulates intestinal NHE8 expression via p38 MAPK pathwayCharacterization of squamous esophageal cells resistant to bile acids at acidic pH: implication for Barrett's esophagus pathogenesis
P2860
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P2860
description
2005 nî lūn-bûn
@nan
2005年の論文
@ja
2005年論文
@yue
2005年論文
@zh-hant
2005年論文
@zh-hk
2005年論文
@zh-mo
2005年論文
@zh-tw
2005年论文
@wuu
2005年论文
@zh
2005年论文
@zh-cn
name
Molecular physiology of intestinal Na+/H+ exchange.
@ast
Molecular physiology of intestinal Na+/H+ exchange.
@en
type
label
Molecular physiology of intestinal Na+/H+ exchange.
@ast
Molecular physiology of intestinal Na+/H+ exchange.
@en
prefLabel
Molecular physiology of intestinal Na+/H+ exchange.
@ast
Molecular physiology of intestinal Na+/H+ exchange.
@en
P2093
P1476
Molecular physiology of intestinal Na+/H+ exchange.
@en
P2093
Mark Donowitz
Nicholas C Zachos
P304
P356
10.1146/ANNUREV.PHYSIOL.67.031103.153004
P577
2005-01-01T00:00:00Z