Ceramide mediates vascular dysfunction in diet-induced obesity by PP2A-mediated dephosphorylation of the eNOS-Akt complex
about
Sphingolipids in High Fat Diet and Obesity-Related DiseasesDihydroceramides: From Bit Players to Lead ActorsLipids and the endothelium: bidirectional interactionsCeramide changes the mediator of flow-induced vasodilation from nitric oxide to hydrogen peroxide in the human microcirculation.Computer-aided targeting of the PI3K/Akt/mTOR pathway: toxicity reduction and therapeutic opportunitiesCeramide as a mediator of non-alcoholic Fatty liver disease and associated atherosclerosisKnockdown of GSK3β increases basal autophagy and AMPK signalling in nutrient-laden human aortic endothelial cellsSphingolipids and phospholipids in insulin resistance and related metabolic disorders.Regulation of obesity and insulin resistance by nitric oxideInsulin Signaling and Heart Failure.Insulin increases ceramide synthesis in skeletal muscleNonalcoholic fatty liver disease and the heart in children and adolescents.Lipotoxicity contributes to endothelial dysfunction: a focus on the contribution from ceramide.Ceramide-activated phosphatase mediates fatty acid-induced endothelial VEGF resistance and impaired angiogenesisGlucose and palmitate uncouple AMPK from autophagy in human aortic endothelial cellsSphingolipid metabolites in inflammatory disease.FM19G11 reverses endothelial dysfunction in rat and human arteries through stimulation of the PI3K/Akt/eNOS pathway, independently of mTOR/HIF-1α activation.Changes in the metabolism of sphingolipids after subarachnoid hemorrhage.Endothelial nitric oxide synthase dimerization is regulated by heat shock protein 90 rather than by phosphorylation.Antiobesogenic role of endothelial nitric oxide synthase.Regulation of glucose and lipid homeostasis by adiponectin: effects on hepatocytes, pancreatic β cells and adipocytesLong-lasting partnership between insulin resistance and endothelial dysfunction: role of metabolic memory.Ceramide-Initiated Protein Phosphatase 2A Activation Contributes to Arterial Dysfunction In Vivo.Diaphragm dysfunction in heart failure is accompanied by increases in neutral sphingomyelinase activity and ceramide contentMechanisms of lipotoxicity in the cardiovascular system.Insulin treatment increases myocardial ceramide accumulation and disrupts cardiometabolic functionInsulin resistance: metabolic mechanisms and consequences in the heart.Ablation of dihydroceramide desaturase 1, a therapeutic target for the treatment of metabolic diseases, simultaneously stimulates anabolic and catabolic signalingOpportunity "nox": a novel approach to preventing endothelial dysfunction in the context of insulin resistance.Sphingolipid metabolism and obesity-induced inflammation.Exercise training improves vascular mitochondrial function.Ectopic and Visceral Fat Deposition in Lean and Obese Patients With Type 2 DiabetesCirculating ceramides are inversely associated with cardiorespiratory fitness in participants aged 54-96 years from the Baltimore Longitudinal Study of Agingγ-Carboxyethyl hydroxychroman, a metabolite of γ-tocopherol, preserves nitric oxide bioavailability in endothelial cells challenged with high glucose.Differential transendothelial transport of adiponectin complexes.Examining the role of insulin in the regulation of cardiovascular health.Molecular biology of atherosclerosis.Insulin regulation of myocardial autophagy.Emerging Role of Nitric Oxide and Heat Shock Proteins in Insulin Resistance.S1P Signaling and De Novo Biosynthesis in Blood Pressure Homeostasis
P2860
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P2860
Ceramide mediates vascular dysfunction in diet-induced obesity by PP2A-mediated dephosphorylation of the eNOS-Akt complex
description
2012 nî lūn-bûn
@nan
2012年の論文
@ja
2012年論文
@yue
2012年論文
@zh-hant
2012年論文
@zh-hk
2012年論文
@zh-mo
2012年論文
@zh-tw
2012年论文
@wuu
2012年论文
@zh
2012年论文
@zh-cn
name
Ceramide mediates vascular dys ...... lation of the eNOS-Akt complex
@ast
Ceramide mediates vascular dys ...... lation of the eNOS-Akt complex
@en
type
label
Ceramide mediates vascular dys ...... lation of the eNOS-Akt complex
@ast
Ceramide mediates vascular dys ...... lation of the eNOS-Akt complex
@en
prefLabel
Ceramide mediates vascular dys ...... lation of the eNOS-Akt complex
@ast
Ceramide mediates vascular dys ...... lation of the eNOS-Akt complex
@en
P2093
P2860
P50
P356
P1433
P1476
Ceramide mediates vascular dys ...... lation of the eNOS-Akt complex
@en
P2093
Alexandrea Nichols
Bradlee Duncan
Christoph Boehme
Christopher A Kowalski
Colton Arrant
Derrick Gale
Devin Kearns
Dix Pettey
J David Symons
Janvida Rou
P2860
P304
P356
10.2337/DB11-1399
P407
P577
2012-05-14T00:00:00Z