Changes in microRNA expression contribute to pancreatic β-cell dysfunction in prediabetic NOD mice - Wikidata - awgldk - TriplyDB

Changes in microRNA expression contribute to pancreatic β-cell dysfunction in prediabetic NOD mice

Changes in microRNA expression contribute to pancreatic β-cell dysfunction in prediabetic NOD mice

http://www.wikidata.org/entity/Q36047577

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New Molecular Insights of Insulin in Diabetic Cardiomyopathy β-Cell MicroRNAs: Small but Powerful MicroRNAs: Novel Players in the Dialogue between Pancreatic Islets and Immune System in Autoimmune Diabetes Epigenetics: the missing link to understanding β-cell dysfunction in the pathogenesis of type 2 diabetes MicroRNAs as pharmacological targets in diabetes MicroRNAs: new insights into chronic childhood diseases The two faces of miR-29 The pathogenic role of persistent milk signaling in mTORC1- and milk-microRNA-driven type 2 diabetes mellitus Can exposure to environmental chemicals increase the risk of diabetes type 1 development?Regulation of cardiac expression of the diabetic marker microRNA miR-29 A Bioinformatics Approach to the Identification of Variants Associated with Type 1 and Type 2 Diabetes Mellitus that Reside in Functionally Validated miRNAs Binding Sites.MCL-1 is modulated in Crohn's disease fibrosis by miR-29b via IL-6 and IL-8 The Biochemical Cascades of the Human Pancreatic β-Cells: The Role of MicroRNAs.AAV-mediated pancreatic overexpression of Igf1 counteracts progression to autoimmune diabetes in mice.miRNAs: novel regulators of autoimmunity-mediated pancreatic β-cell destruction in type 1 diabetes.MicroRNA-29b modulates innate and antigen-specific immune responses in mouse models of autoimmunity Identifying common and specific microRNAs expressed in peripheral blood mononuclear cell of type 1, type 2, and gestational diabetes mellitus patients.MicroRNA expression in alpha and beta cells of human pancreatic islets.Minireview: microRNA function in pancreatic β cells.Beta cell 5'-shifted isomiRs are candidate regulatory hubs in type 2 diabetes.MicroRNA 29 targets nuclear factor-κB-repressing factor and Claudin 1 to increase intestinal permeability.Horizontal transfer of exosomal microRNAs transduce apoptotic signals between pancreatic beta-cells.Micro-RNA Binding Site Polymorphisms in the WFS1 Gene Are Risk Factors of Diabetes Mellitus.Addressing Bias in Small RNA Library Preparation for Sequencing: A New Protocol Recovers MicroRNAs that Evade Capture by Current Methods.On the immense variety and complexity of circumstances conditioning pancreatic β-cell apoptosis in type 1 diabetes MicroRNAs miR-23a-3p, miR-23b-3p, and miR-149-5p Regulate the Expression of Proapoptotic BH3-Only Proteins DP5 and PUMA in Human Pancreatic β-Cells.The miRNA Interactome in Metabolic Homeostasis Update on the protective molecular pathways improving pancreatic beta-cell dysfunction The microRNA-29 Family Dictates the Balance Between Homeostatic and Pathological Glucose Handling in Diabetes and Obesity.Urine miRNAs: potential biomarkers for monitoring progression of early stages of diabetic nephropathy.MiR-206 is expressed in pancreatic islets and regulates glucokinase activity Increased expression of miR-187 in human islets from individuals with type 2 diabetes is associated with reduced glucose-stimulated insulin secretion.The pancreatic β cell and type 1 diabetes: innocent bystander or active participant?MiRNAs in β-Cell Development, Identity, and Disease.Epigenetic regulation of pancreatic islets.Candidate genes for type 1 diabetes modulate pancreatic islet inflammation and β-cell apoptosis.Role of non-coding RNAs in pancreatic beta-cell development and physiology.Regulation of Pancreatic Beta Cell Stimulus-Secretion Coupling by microRNAs.Noncoding RNAs in β cell biology Circulating miRNAs as intercellular messengers, potential biomarkers and therapeutic targets for Type 2 diabetes.

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Changes in microRNA expression contribute to pancreatic β-cell dysfunction in prediabetic NOD mice

http://www.wikidata.org/entity/Q36047577

description

2012 nî lūn-bûn

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2012年の論文

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2012年論文

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2012年論文

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2012年論文

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2012年論文

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2012年論文

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2012年论文

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2012年论文

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2012年论文

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name

Changes in microRNA expression ...... nction in prediabetic NOD mice

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Changes in microRNA expression ...... nction in prediabetic NOD mice

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Changes in microRNA expression ...... nction in prediabetic NOD mice

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Changes in microRNA expression ...... nction in prediabetic NOD mice

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prefLabel

Changes in microRNA expression ...... nction in prediabetic NOD mice

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Changes in microRNA expression ...... nction in prediabetic NOD mice

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Changes in microRNA expression ...... nction in prediabetic NOD mice

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Claire Briet

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Dorothée Caille

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Elodie Roggli

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Paolo Meda

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Romano Regazzi

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Sonia Gattesco

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P2860

The promoter of the pri-miR-375 gene directs expression selectively to the endocrine pancreas

Targeted inhibition of miRNA maturation with morpholinos reveals a role for miR-375 in pancreatic islet development

The transcriptional repressor REST determines the cell-specific expression of the human MAPK8IP1 gene encoding IB1 (JIP-1)

Junctional communication of pancreatic beta cells contributes to the control of insulin secretion and glucose tolerance

miR-375 targets 3'-phosphoinositide-dependent protein kinase-1 and regulates glucose-induced biological responses in pancreatic beta-cells

mir-29 regulates Mcl-1 protein expression and apoptosis

miR-375 maintains normal pancreatic alpha- and beta-cell mass

Mammalian microRNAs predominantly act to decrease target mRNA levels

Conserved seed pairing, often flanked by adenosines, indicates that thousands of human genes are microRNA targets

MicroRNAs: genomics, biogenesis, mechanism, and function

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1742-1751

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10.2337/DB11-1086

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7

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61

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Christian Boitard

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2012-04-26T00:00:00Z

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224854292

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22537941

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P921

microRNA expression

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3379668

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