Inferring somatic mutation rates using the stop-enhanced green fluorescent protein mouse

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Transgenic mouse model expressing P53(R172H), luciferase, EGFP, and KRAS(G12D) in a single open reading frame for live imaging of tumor.Ignoring heterozygous sites biases phylogenomic estimates of divergence times: implications for the evolutionary history of microtus voles.

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Inferring somatic mutation rates using the stop-enhanced green fluorescent protein mouse

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2007 nî lūn-bûn

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2007年の論文

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2007年論文

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2007年論文

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2007年論文

@zh-hk

2007年論文

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2007年論文

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2007年论文

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Inferring somatic mutation rates using the stop-enhanced green fluorescent protein mouse

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Inferring somatic mutation rates using the stop-enhanced green fluorescent protein mouse

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Inferring somatic mutation rates using the stop-enhanced green fluorescent protein mouse

@ast

Inferring somatic mutation rates using the stop-enhanced green fluorescent protein mouse

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Inferring somatic mutation rates using the stop-enhanced green fluorescent protein mouse

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Inferring somatic mutation rates using the stop-enhanced green fluorescent protein mouse

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P1476

Inferring somatic mutation rates using the stop-enhanced green fluorescent protein mouse

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Bruce Rannala

http://www.w3.org/2001/XMLSchema#string

Simon Ro

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The Hallmarks of Cancer

The clonal evolution of tumor cell populations

Magnifying stem cell lineages: the stop-EGFP mouse.

On clonal expansion and its effects on mutant frequencies, mutation spectra and statistics for somatic mutations in vivo.

Mutant manifestation: the time factor in somatic mutagenesis.

Transgenic mouse mutation assay systems can play an important role in regulatory mutagenicity testing in vivo for the detection of site-of-contact mutagens.

Altered spectra of hypermutation in DNA repair-deficient mice.

Cancer genetics.

Efficient rescue of integrated shuttle vectors from transgenic mice: a model for studying mutations in vivo

ENU mutagenesis: analyzing gene function in mice.

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9-16

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scholarly article

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10.1534/GENETICS.106.069310

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English

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http://www.w3.org/2001/XMLSchema#string

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177

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2007-07-01T00:00:00Z

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6234739

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17603123

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2013726

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Inferring somatic mutation rates using the stop-enhanced green fluorescent protein mouse

about

P2860

P2860

Inferring somatic mutation rates using the stop-enhanced green fluorescent protein mouse

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P1433

P1476

P2093

P2860

P304

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P356

P407

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P5875

P698

P932

P356

P1433

P1476

P2093

P2860

P304

P31

P356

P407

P433

P478

P577

P5875

P698

P932