Zinc transporter-2 (ZnT2) variants are localized to distinct subcellular compartments and functionally transport zinc.
about
Zinc transporter 8 (ZnT8) and β cell functionttm-1 encodes CDF transporters that excrete zinc from intestinal cells of C. elegans and act in a parallel negative feedback circuit that promotes homeostasisZinc and zinc transporter regulation in pancreatic islets and the potential role of zinc in islet transplantationGenome wide identification, phylogeny and expression of zinc transporter genes in common carpMapping the zinc-transporting system in mammary cells: molecular analysis reveals a phenotype-dependent zinc-transporting network during lactationX-ray fluorescence microscopy reveals accumulation and secretion of discrete intracellular zinc pools in the lactating mouse mammary gland.Spliced leader trapping reveals widespread alternative splicing patterns in the highly dynamic transcriptome of Trypanosoma brucei.Zinc transporter expression profiles in the rat prostate following alterations in dietary zincProlactin (PRL)-stimulated ubiquitination of ZnT2 mediates a transient increase in zinc secretion followed by ZnT2 degradation in mammary epithelial cells.Zinc bells rang in Jerusalem!Functional analysis of two single nucleotide polymorphisms in SLC30A2 (ZnT2): implications for mammary gland function and breast disease in womenZinc in specialized secretory tissues: roles in the pancreas, prostate, and mammary gland.ZnT2 is a critical mediator of lysosomal-mediated cell death during early mammary gland involution.Paradoxical zinc toxicity and oxidative stress in the mammary gland during marginal dietary zinc deficiency.A histidine-rich motif mediates mitochondrial localization of ZnT2 to modulate mitochondrial functionHeterodimerization, altered subcellular localization, and function of multiple zinc transporters in viable cells using bimolecular fluorescence complementationMarginal maternal zinc deficiency in lactating mice reduces secretory capacity and alters milk compositionEssential Role for Zinc Transporter 2 (ZnT2)-mediated Zinc Transport in Mammary Gland Development and Function during Lactation.Obesity-Induced Inflammation Is Associated with Alterations in Subcellular Zinc Pools and Premature Mammary Gland Involution in Lactating Mice.ZnT4 provides zinc to zinc-dependent proteins in the trans-Golgi network critical for cell function and Zn export in mammary epithelial cells.Transition metals activate TFEB in overexpressing cellsWhole-Genome Resequencing of Holstein Bulls for Indel Discovery and Identification of Genes Associated with Milk Composition Traits in Dairy Cattle.Subtype-specific accumulation of intracellular zinc pools is associated with the malignant phenotype in breast cancer.Zinc-dependent lysosomal enlargement in TRPML1-deficient cells involves MTF-1 transcription factor and ZnT4 (Slc30a4) transporterMammary gland zinc metabolism: regulation and dysregulation.ZnT2-Mediated Zinc Import Into Paneth Cell Granules Is Necessary for Coordinated Secretion and Paneth Cell Function in Mice.Upregulation of zinc transporter 2 in the blood-CSF barrier following lead exposureThe biology of zinc transport in mammary epithelial cells: implications for mammary gland development, lactation, and involution.Cation Diffusion Facilitator family: Structure and function.The secret life of extracellular vesicles in metal homeostasis and neurodegeneration.The Physiological, Biochemical, and Molecular Roles of Zinc Transporters in Zinc Homeostasis and Metabolism.TNFα Post-Translationally Targets ZnT2 to Accumulate Zinc in Lysosomes.The mucolipin-1 (TRPML1) ion channel, transmembrane-163 (TMEM163) protein, and lysosomal zinc handling.Modulation of Zinc Homeostasis in Acanthamoeba castellanii as a Possible Antifungal Strategy against Cryptococcus gattii.In vivo zinc toxicity phenotypes provide a sensitized background that suggests zinc transport activities for most of the Drosophila Zip and ZnT genes.Effects of zinc transporter on differentiation of bone marrow mesenchymal stem cells to osteoblasts.Zinc transporter 2 interacts with vacuolar ATPase and is required for polarization, vesicle acidification, and secretion in mammary epithelial cells.Zinc Dyshomeostasis in Cardiomyocytes after Acute Hypoxia/Reoxygenation.A genetic variant in SLC30A2 causes breast dysfunction during lactation by inducing ER stress, oxidative stress and epithelial barrier defects.
P2860
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P2860
Zinc transporter-2 (ZnT2) variants are localized to distinct subcellular compartments and functionally transport zinc.
description
2009 nî lūn-bûn
@nan
2009年の論文
@ja
2009年論文
@yue
2009年論文
@zh-hant
2009年論文
@zh-hk
2009年論文
@zh-mo
2009年論文
@zh-tw
2009年论文
@wuu
2009年论文
@zh
2009年论文
@zh-cn
name
Zinc transporter-2 (ZnT2) vari ...... d functionally transport zinc.
@ast
Zinc transporter-2 (ZnT2) vari ...... d functionally transport zinc.
@en
type
label
Zinc transporter-2 (ZnT2) vari ...... d functionally transport zinc.
@ast
Zinc transporter-2 (ZnT2) vari ...... d functionally transport zinc.
@en
prefLabel
Zinc transporter-2 (ZnT2) vari ...... d functionally transport zinc.
@ast
Zinc transporter-2 (ZnT2) vari ...... d functionally transport zinc.
@en
P2860
P356
P1433
P1476
Zinc transporter-2 (ZnT2) vari ...... d functionally transport zinc.
@en
P2093
Shannon L Kelleher
Veronica Lopez
P2860
P356
10.1042/BJ20081189
P407
P577
2009-07-29T00:00:00Z