about
MicroRNAs in liver fibrosis: Focusing on the interaction with hedgehog signalingHedgehog signaling: modulation of cancer properies and tumor mircroenvironmentAberrant GLI1 Activation in DNA Damage Response, Carcinogenesis and ChemoresistanceHedgehog signaling pathway and its targets for treatment in basal cell carcinomaCyclopamine tartrate, an inhibitor of Hedgehog signaling, strongly interferes with mitochondrial function and suppresses aerobic respiration in lung cancer cellsA novel PEGylated liposome-encapsulated SANT75 suppresses tumor growth through inhibiting hedgehog signaling pathwayHedgehog/Gli promotes epithelial-mesenchymal transition in lung squamous cell carcinomas.Gli as a novel therapeutic target in malignant pleural mesotheliomaDiscovery of small-molecule modulators of the Sonic Hedgehog pathway.Combination therapy of prostate cancer with HPMA copolymer conjugates containing PI3K/mTOR inhibitor and docetaxelSynthetic Small Molecule Inhibitors of Hh Signaling As Anti-Cancer Chemotherapeutics.Patched knockout mouse models of Basal cell carcinoma.The Hedgehog signalling pathway in breast development, carcinogenesis and cancer therapy.Differential pharmacology and clinical utility of sonidegib in advanced basal cell carcinoma.Gli promotes epithelial-mesenchymal transition in human lung adenocarcinomasMedical approaches to non-melanoma skin cancer.Paracrine signaling in stem cell renewal and in neoplastic tumor growth.Establishment of basal cell carcinoma animal model in Chinese tree shrew (Tupaia belangeri chinensis).Imiquimod directly inhibits Hedgehog signalling by stimulating adenosine receptor/protein kinase A-mediated GLI phosphorylation.Hedgehog pathway inhibitors - current status and future prospects.Present status and upcoming prospects of hedgehog pathway inhibitors in small cell lung cancer therapy.An old friend with new skills: Imiquimod as novel inhibitor of Hedgehog signaling in basal cell carcinoma.Hedgehog-targeted therapeutics uncouple the vicious cycle of bone metastasis.Targeted treatments for metastatic esophageal squamous cell cancerTargeting Class I Histone Deacetylases by the Novel Small Molecule Inhibitor 4SC-202 Blocks Oncogenic Hedgehog-GLI Signaling and Overcomes Smoothened Inhibitor Resistance.Molecular docking approaches in identification of High affinity inhibitors of Human SMO receptor.Strategies to target the Hedgehog signaling pathway for cancer therapy.Gli is activated and promotes epithelial-mesenchymal transition in human esophageal adenocarcinoma.Chemical, computational and functional insights into the chemical stability of the Hedgehog pathway inhibitor GANT61.Roles of the Hedgehog Signaling Pathway in Epidermal and Hair Follicle Development, Homeostasis, and Cancer.Novel molecular insights and new therapeutic strategies in osteosarcomaA structurally guided dissection-then-evolution strategy for ligand optimization of smoothened receptor
P2860
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P2860
description
2012 nî lūn-bûn
@nan
2012年の論文
@ja
2012年論文
@yue
2012年論文
@zh-hant
2012年論文
@zh-hk
2012年論文
@zh-mo
2012年論文
@zh-tw
2012年论文
@wuu
2012年论文
@zh
2012年论文
@zh-cn
name
Vismodegib.
@ast
Vismodegib.
@en
type
label
Vismodegib.
@ast
Vismodegib.
@en
prefLabel
Vismodegib.
@ast
Vismodegib.
@en
P2093
P2860
P356
P1476
Vismodegib.
@en
P2093
Andrzej Dlugosz
Peter Kirkpatrick
Sid Agrawal
P2860
P2888
P304
P356
10.1038/NRD3753
P577
2012-06-01T00:00:00Z