Distinct roles of mitochondria- and ER-localized Bcl-xL in apoptosis resistance and Ca2+ homeostasis
about
Bcl-xL regulates CD1d-mediated antigen presentation to NKT cells by altering CD1d trafficking through the endocytic pathway.The BH4 domain of anti-apoptotic Bcl-XL, but not that of the related Bcl-2, limits the voltage-dependent anion channel 1 (VDAC1)-mediated transfer of pro-apoptotic Ca2+ signals to mitochondria.Structural transition in Bcl-xL and its potential association with mitochondrial calcium ion transportActivation of Type I and III Interferon Response by Mitochondrial and Peroxisomal MAVS and Inhibition by Hepatitis C Virus.Ceramide channels: destabilization by Bcl-xL and role in apoptosisDissecting the in vivo leukemogenic potency of BCLxl.An interaction between Bcl-xL and the voltage-dependent anion channel (VDAC) promotes mitochondrial Ca2+ uptake.The apoptotic members CD95, BclxL, and Bcl-2 cooperate to promote cell migration by inducing Ca(2+) flux from the endoplasmic reticulum to mitochondria.The selective BH4-domain biology of Bcl-2-family members: IP3Rs and beyond.Oncogenic and oncosuppressive signal transduction at mitochondria-associated endoplasmic reticulum membranesSuppression of PI3K/Akt signaling by synthetic bichalcone analog TSWU-CD4 induces ER stress- and Bax/Bak-mediated apoptosis of cancer cells.Interaction of Mitochondria with the Endoplasmic Reticulum and Plasma Membrane in Calcium Homeostasis, Lipid Trafficking and Mitochondrial StructurePACS-2 mediates the ATM and NF-κB-dependent induction of anti-apoptotic Bcl-xL in response to DNA damageNoxa couples lysosomal membrane permeabilization and apoptosis during oxidative stress.Ingenol mebutate: potential for further development of cancer immunotherapy.Apoptotic cell death and altered calcium homeostasis caused by frataxin depletion in dorsal root ganglia neurons can be prevented by BH4 domain of Bcl-xL protein.Transmembrane E3 ligase RNF183 mediates ER stress-induced apoptosis by degrading Bcl-xL.
P2860
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P2860
Distinct roles of mitochondria- and ER-localized Bcl-xL in apoptosis resistance and Ca2+ homeostasis
description
2012 nî lūn-bûn
@nan
2012年の論文
@ja
2012年論文
@yue
2012年論文
@zh-hant
2012年論文
@zh-hk
2012年論文
@zh-mo
2012年論文
@zh-tw
2012年论文
@wuu
2012年论文
@zh
2012年论文
@zh-cn
name
Distinct roles of mitochondria ...... esistance and Ca2+ homeostasis
@ast
Distinct roles of mitochondria ...... esistance and Ca2+ homeostasis
@en
type
label
Distinct roles of mitochondria ...... esistance and Ca2+ homeostasis
@ast
Distinct roles of mitochondria ...... esistance and Ca2+ homeostasis
@en
prefLabel
Distinct roles of mitochondria ...... esistance and Ca2+ homeostasis
@ast
Distinct roles of mitochondria ...... esistance and Ca2+ homeostasis
@en
P2093
P2860
P356
P1476
Distinct roles of mitochondria ...... esistance and Ca2+ homeostasis
@en
P2093
Carl White
Colins O Eno
Emily F Eckenrode
Guoping Zhao
Kristen E Olberding
P2860
P304
P356
10.1091/MBC.E12-02-0090
P577
2012-05-09T00:00:00Z