Frontotemporal dementia caused by CHMP2B mutation is characterised by neuronal lysosomal storage pathology.

Frontotemporal dementia caused by CHMP2B mutation is characterised by neuronal lysosomal storage pathology.

Item
http://www.wikidata.org/entity/Q36073666
Early microgliosis precedes neuronal loss and behavioural impairment in mice with a frontotemporal dementia-causing CHMP2B mutationESCRT-III and Vps4: a dynamic multipurpose tool for membrane budding and scission.The role of CHMP2BIntron5 in autophagy and frontotemporal dementia.Genetics of FTLD: overview and what else we can expect from genetic studies.Monoaminergic neuropathology in Alzheimer's disease.Endo-lysosomal and autophagic dysfunction: a driving factor in Alzheimer's disease?Oligodendroglial deletion of ESCRT-I component TSG101 causes spongiform encephalopathy.A transgenic mouse expressing CHMP2Bintron5 mutant in neurons develops histological and behavioural features of amyotrophic lateral sclerosis and frontotemporal dementia.Commentary: Possible involvement of lysosomal dysfunction in pathological changes of the brain in aged progranulin-deficient miceCSF neurofilament light concentration is increased in presymptomatic CHMP2B mutation carriers.Dysregulated molecular pathways in amyotrophic lateral sclerosis-frontotemporal dementia spectrum disorder.Dysfunction of autophagy and endosomal-lysosomal pathways: Roles in pathogenesis of Down syndrome and Alzheimer's Disease.Molecular Genetics of Frontotemporal Dementia Elucidated by Drosophila Models-Defects in Endosomal⁻Lysosomal Pathway.
P2860

Frontotemporal dementia caused by CHMP2B mutation is characterised by neuronal lysosomal storage pathology.

Item
http://www.wikidata.org/entity/Q36073666
description
2015 nî lūn-bûn
@nan
2015年の論文
@ja
2015年学术文章
@wuu
2015年学术文章
@zh-cn
2015年学术文章
@zh-hans
2015年学术文章
@zh-my
2015年学术文章
@zh-sg
2015年學術文章
@yue
2015年學術文章
@zh
2015年學術文章
@zh-hant
name
Frontotemporal dementia caused ...... l lysosomal storage pathology.
@ast
Frontotemporal dementia caused ...... l lysosomal storage pathology.
@en
type
label
Frontotemporal dementia caused ...... l lysosomal storage pathology.
@ast
Frontotemporal dementia caused ...... l lysosomal storage pathology.
@en
prefLabel
Frontotemporal dementia caused ...... l lysosomal storage pathology.
@ast
Frontotemporal dementia caused ...... l lysosomal storage pathology.
@en
P1433
P1476
P2093
P2860
P2888
P304
P31
P356
P433
P478
P50
P577
P5875
P698
P921
P932
P356
P1433
P1476
Frontotemporal dementia caused ...... l lysosomal storage pathology.
@en
P2093
P2860
P2888
P304
P31
P356
P433
P478
P50
P577
P5875
P698
P921
P932