Single-cell transcriptomic reconstruction reveals cell cycle and multi-lineage differentiation defects in Bcl11a-deficient hematopoietic stem cells.
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Customizing the genome as therapy for the β-hemoglobinopathiesDesign and computational analysis of single-cell RNA-sequencing experimentsSingle-cell sequencing in stem cell biologySingle-cell technologies are revolutionizing the approach to rare cellsIdentifying and removing the cell-cycle effect from single-cell RNA-Sequencing data.Single cell transcriptomics reveals unanticipated features of early hematopoietic precursorsEpigenetic Memory Underlies Cell-Autonomous Heterogeneous Behavior of Hematopoietic Stem CellsSingle Cell RNA-Sequencing of Pluripotent States Unlocks Modular Transcriptional Variation.Order Under Uncertainty: Robust Differential Expression Analysis Using Probabilistic Models for Pseudotime Inference.Single-cell RNA sequencing reveals molecular and functional platelet bias of aged haematopoietic stem cells.Progressive alterations in multipotent hematopoietic progenitors underlie lymphoid cell loss in aging.Lineage-specific BCL11A knockdown circumvents toxicities and reverses sickle phenotype.Transcriptomic signatures shaped by cell proportions shed light on comparative developmental biology.Long-Term Engraftment and Fetal Globin Induction upon BCL11A Gene Editing in Bone-Marrow-Derived CD34+ Hematopoietic Stem and Progenitor Cells.Single-cell RNA sequencing to explore immune cell heterogeneity.Molecular landscapes of human hematopoietic stem cells in health and leukemia.JingleBells: A Repository of Immune-Related Single-Cell RNA-Sequencing Datasets.Use of genome-editing tools to treat sickle cell disease.Hemoglobin genetics: recent contributions of GWAS and gene editing.Gene Therapy for β-Hemoglobinopathies.Bcl11a Deficiency Leads to Hematopoietic Stem Cell Defects with an Aging-like Phenotype.Single-cell analysis reveals key roles for Bcl11a in regulating stem cell fate decisionsSingle-cell transcriptomics to explore the immune system in health and disease.Transcription Factor CTIP1/ BCL11A Regulates Epidermal Differentiation and Lipid Metabolism During Skin Development.Single cell analysis of normal and leukemic hematopoiesis.Global and targeted approaches to single-cell transcriptome characterization.Single-cell genomics: coming of ageStrict in vivo specificity of the Bcl11a erythroid enhancer.Recent progress in understanding and manipulating haemoglobin switching for the haemoglobinopathies.The Human Cell Atlas.Alternative Polyadenylation: Methods, Findings, and Impacts.Concise Review: Epigenetic Regulation of Hematopoiesis: Biological Insights and Therapeutic Applications.Single-cell RNA sequencing reveals developmental heterogeneity among early lymphoid progenitors.Gene Therapy for Hemoglobinopathies
P2860
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P2860
Single-cell transcriptomic reconstruction reveals cell cycle and multi-lineage differentiation defects in Bcl11a-deficient hematopoietic stem cells.
description
2015 nî lūn-bûn
@nan
2015年の論文
@ja
2015年論文
@yue
2015年論文
@zh-hant
2015年論文
@zh-hk
2015年論文
@zh-mo
2015年論文
@zh-tw
2015年论文
@wuu
2015年论文
@zh
2015年论文
@zh-cn
name
Single-cell transcriptomic rec ...... ient hematopoietic stem cells.
@ast
Single-cell transcriptomic rec ...... ient hematopoietic stem cells.
@en
type
label
Single-cell transcriptomic rec ...... ient hematopoietic stem cells.
@ast
Single-cell transcriptomic rec ...... ient hematopoietic stem cells.
@en
prefLabel
Single-cell transcriptomic rec ...... ient hematopoietic stem cells.
@ast
Single-cell transcriptomic rec ...... ient hematopoietic stem cells.
@en
P2093
P2860
P50
P1433
P1476
Single-cell transcriptomic rec ...... ient hematopoietic stem cells.
@en
P2093
Jason C H Tsang
Pentao Liu
Shannon Burke
P2860
P2888
P356
10.1186/S13059-015-0739-5
P577
2015-09-21T00:00:00Z
P5875
P6179
1037702483