Cross-species transcriptional network analysis defines shared inflammatory responses in murine and human lupus nephritis - Wikidata - awgldk - TriplyDB

Cross-species transcriptional network analysis defines shared inflammatory responses in murine and human lupus nephritis

Cross-species transcriptional network analysis defines shared inflammatory responses in murine and human lupus nephritis

http://www.wikidata.org/entity/Q36083938

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Pro: 'The usefulness of biomarkers in glomerular diseases'. The problem: moving from syndrome to mechanism--individual patient variability in disease presentation, course and response to therapy Current perspectives on systems immunology approaches to rheumatic diseases.Applications of systems approaches in the study of rheumatic diseases.Silica Triggers Inflammation and Ectopic Lymphoid Neogenesis in the Lungs in Parallel with Accelerated Onset of Systemic Autoimmunity and Glomerulonephritis in the Lupus-Prone NZBWF1 Mouse Demethylzeylasteral (T-96) Treatment Ameliorates Mice Lupus Nephritis Accompanied by Inhibiting Activation of NF-κB Pathway Drug repositioning in SLE: crowd-sourcing, literature-mining and Big Data analysis.MXRA5 is a TGF-β1-regulated human protein with anti-inflammatory and anti-fibrotic properties Integrative biology identifies shared transcriptional networks in CKD.Human systems immunology: hypothesis-based modeling and unbiased data-driven approaches.Comparative transcriptional profiling of 3 murine models of SLE nephritis reveals both unique and shared regulatory networks.Biomarkers for kidney involvement in pediatric lupus.Structure and function of renal macrophages and dendritic cells from lupus-prone mice Identification of stage-specific genes associated with lupus nephritis and response to remission induction in (NZB × NZW)F1 and NZM2410 mice.Identification of potential candidate genes for hypertensive nephropathy based on gene expression profile.Pristane-Accelerated Autoimmune Disease in (SWR X NZB) F1 Mice Leads to Prominent Tubulointerstitial Inflammation and Human Lupus Nephritis-Like Fibrosis.The Pathogenesis and Therapeutic Implications of Tubulointerstitial Inflammation in Human Lupus Nephritis Characterising the immune profile of the kidney biopsy at lupus nephritis flare differentiates early treatment responders from non-responders What is damaging the kidney in lupus nephritis?Tissue transcriptome-driven identification of epidermal growth factor as a chronic kidney disease biomarker From single nucleotide polymorphism to transcriptional mechanism: a model for FRMD3 in diabetic nephropathy.A replication study from Chinese supports association between lupus-risk allele in TNFSF4 and renal disorder.Defining cell-type specificity at the transcriptional level in human disease Btk-specific inhibition blocks pathogenic plasma cell signatures and myeloid cell-associated damage in IFNα-driven lupus nephritis.Tet3-mediated hydroxymethylation of epigenetically silenced genes contributes to bone morphogenic protein 7-induced reversal of kidney fibrosis.Gene expression and regulation in systemic lupus erythematosus.Genomewide effects of peroxisome proliferator-activated receptor gamma in macrophages and dendritic cells--revealing complexity through systems biology.Molecular studies of lupus nephritis kidneys.Modular transcriptional repertoire analyses identify a blood neutrophil signature as a candidate biomarker for lupus nephritis.Overview of pathophysiology and treatment of human lupus nephritis.A systems approach to renal inflammation in SLE.The contribution of the programmed cell death machinery in innate immune cells to lupus nephritis.The Role of MicroRNAs and Human Epidermal Growth Factor Receptor 2 in Proliferative Lupus Nephritis.xHeinz: an algorithm for mining cross-species network modules under a flexible conservation model.Bcl3: a regulator of NF-κB inducible by TWEAK in acute kidney injury with anti-inflammatory and antiapoptotic properties in tubular cells.Non-canonical NFκB activation promotes chemokine expression in podocytes The kidney biopsy in lupus nephritis: is it still relevant?Which B-cell subset should we target in lupus?Micro-RNA analysis of renal biopsies in human lupus nephritis demonstrates up-regulated miR-422a driving reduction of kallikrein-related peptidase 4.Bim suppresses the development of SLE by limiting myeloid inflammatory responses.Renal Macrophages and Dendritic Cells in SLE Nephritis.

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Cross-species transcriptional network analysis defines shared inflammatory responses in murine and human lupus nephritis

http://www.wikidata.org/entity/Q36083938

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Cross-species transcriptional ...... rine and human lupus nephritis

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Cross-species transcriptional ...... rine and human lupus nephritis

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Cross-species transcriptional ...... rine and human lupus nephritis

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Cross-species transcriptional ...... rine and human lupus nephritis

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Cross-species transcriptional ...... rine and human lupus nephritis

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Journal of Immunology

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Cross-species transcriptional ...... rine and human lupus nephritis

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Celine C Berthier

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Clemens D Cohen

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Erwin P Bottinger

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Maja Lindenmeyer

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Matthias Kretzler

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Meera Ramanujam

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Tania Gonzalez-Rivera

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Viji Nair

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Weijia Zhang

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P2860

Accurate normalization of real-time quantitative RT-PCR data by geometric averaging of multiple internal control genes

Differential involvement of Src family kinases in Fc gamma receptor-mediated phagocytosis

Of mice and not men: differences between mouse and human immunology

The peroxisome proliferator-activated receptor gamma agonist rosiglitazone ameliorates murine lupus by induction of adiponectin

Integration of biological networks and gene expression data using Cytoscape

TM4: a free, open-source system for microarray data management and analysis

Adjusting batch effects in microarray expression data using empirical Bayes methods

TM4 microarray software suite

The detrimental effects of IFN-α on vasculogenesis in lupus are mediated by repression of IL-1 pathways: potential role in atherogenesis and renal vascular rarefaction.

CX3CR1+ interstitial dendritic cells form a contiguous network throughout the entire kidney.

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988-1001

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10.4049/JIMMUNOL.1103031

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2

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189

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Ramalingam Bethunaickan

Stephan Segerer

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2012-06-20T00:00:00Z

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227857969

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22723521

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3392438

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