Antimalarial activity of the anticancer histone deacetylase inhibitor SB939. - Wikidata - awgldk - TriplyDB

Antimalarial activity of the anticancer histone deacetylase inhibitor SB939.

Antimalarial activity of the anticancer histone deacetylase inhibitor SB939.

http://www.wikidata.org/entity/Q36086326

about

Alternatives to currently used antimalarial drugs: in search of a magic bullet Macrolides rapidly inhibit red blood cell invasion by the human malaria parasite, Plasmodium falciparum.Lysine acetylation in sexual stage malaria parasites is a target for antimalarial small molecules.Production and characterization of specific monoclonal antibodies binding the Plasmodium falciparum diagnostic biomarker, histidine-rich protein 2 Valproic acid as a potential inhibitor of Plasmodium falciparum histone deacetylase 1 (PfHDAC1): an in silico approach.Discovery of HDAC inhibitors with potent activity against multiple malaria parasite life cycle stages A pantetheinase-resistant pantothenamide with potent, on-target, and selective antiplasmodial activity A serine-arginine-rich (SR) splicing factor modulates alternative splicing of over a thousand genes in Toxoplasma gondii.Profiling the anti-protozoal activity of anti-cancer HDAC inhibitors against Plasmodium and Trypanosoma parasites Design and Synthesis of Novel Anti-Plasmodial Histone Deacetylase Inhibitors Containing an Alkoxyamide Connecting Unit.Discovery of a Selective Series of Inhibitors of Plasmodium falciparum HDACs Effect of clinically approved HDAC inhibitors on Plasmodium, Leishmania and Schistosoma parasite growth.Antiplasmodial drug targets: a patent review (2000 - 2013).Transcriptional Profiling Defines Histone Acetylation as a Regulator of Gene Expression during Human-to-Mosquito Transmission of the Malaria Parasite Plasmodium falciparum.Synthesis, antimalarial properties, and SAR studies of alkoxyurea-based HDAC inhibitors.Design and Synthesis of Terephthalic Acid-Based Histone Deacetylase Inhibitors with Dual-Stage Anti-Plasmodium Activity.Histone lysine methyltransferase structure activity relationships that allow for segregation of G9a inhibition and anti-Plasmodium activity† †The authors declare no competing interests. ‡ ‡Electronic supplementary information (ESI) available: Supple Histone lysine methyltransferase structure activity relationships that allow for segregation of G9a inhibition and anti-Plasmodium activity.Improper protein trafficking contributes to artemisinin sensitivity in cells lacking the KDAC Rpd3p.Cancer and parasitic infections: similarities and opportunities for the development of new control tools

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P2860

Antimalarial activity of the anticancer histone deacetylase inhibitor SB939.

http://www.wikidata.org/entity/Q36086326

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2012 nî lūn-bûn

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2012年の論文

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2012年論文

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2012年論文

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2012年論文

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2012年論文

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2012年論文

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2012年论文

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2012年论文

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2012年论文

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name

Antimalarial activity of the anticancer histone deacetylase inhibitor SB939.

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Antimalarial activity of the anticancer histone deacetylase inhibitor SB939.

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type

label

Antimalarial activity of the anticancer histone deacetylase inhibitor SB939.

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Antimalarial activity of the anticancer histone deacetylase inhibitor SB939.

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Antimalarial activity of the anticancer histone deacetylase inhibitor SB939.

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Antimalarial activity of the anticancer histone deacetylase inhibitor SB939.

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Antimicrobial Agents and Chemotherapy

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Antimalarial activity of the anticancer histone deacetylase inhibitor SB939.

@en

P2093

Christopher D Goodman

http://www.w3.org/2001/XMLSchema#string

Katherine T Andrews

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Subathdrage D M Sumanadasa

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Tram Anh Do

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P2860

Artemisinin Resistance in Plasmodium falciparum Malaria

CLUSTAL W: improving the sensitivity of progressive multiple sequence alignment through sequence weighting, position-specific gap penalties and weight matrix choice

Cloning and functional characterization of HDAC11, a novel member of the human histone deacetylase family

HDAC6 modulates Hsp90 chaperone activity and regulates activation of aryl hydrocarbon receptor signaling

The Protein Data Bank

Potencies of human immunodeficiency virus protease inhibitors in vitro against Plasmodium falciparum and in vivo against murine malaria

Basic local alignment search tool

Structures of a histone deacetylase homologue bound to the TSA and SAHA inhibitors

Exploration of the HDAC2 foot pocket: Synthesis and SAR of substituted N-(2-aminophenyl)benzamides

Comparative protein modelling by satisfaction of spatial restraints

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3849-3856

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10.1128/AAC.00030-12

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7

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56

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Geoffrey Ian McFadden

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224052258

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