Atrogin-1 inhibits Akt-dependent cardiac hypertrophy in mice via ubiquitin-dependent coactivation of Forkhead proteins. - Wikidata - awgldk - TriplyDB

Atrogin-1 inhibits Akt-dependent cardiac hypertrophy in mice via ubiquitin-dependent coactivation of Forkhead proteins.

Atrogin-1 inhibits Akt-dependent cardiac hypertrophy in mice via ubiquitin-dependent coactivation of Forkhead proteins.

http://www.wikidata.org/entity/Q36088932

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Atrogin-1 and MuRF1 regulate cardiac MyBP-C levels via different mechanisms Regulation of the stability and transcriptional activity of NFATc4 by ubiquitination miR-9 and NFATc3 regulate myocardin in cardiac hypertrophy Cullin-RING ligases in regulation of autophagy Ongoing controversies surrounding cardiac remodeling: is it black and white-or rather fifty shades of gray?The ubiquitin-proteasome system and cardiovascular disease Targeting the ubiquitin-proteasome system in heart disease: the basis for new therapeutic strategies A substitution mutation in cardiac ubiquitin ligase, FBXO32, is associated with an autosomal recessive form of dilated cardiomyopathy Regulation of Abro1/KIAA0157 during myocardial infarction and cell death reveals a novel cardioprotective mechanism for Lys63-specific deubiquitination The miR-19a/b family positively regulates cardiomyocyte hypertrophy by targeting atrogin-1 and MuRF-1 Inhibition of atrogin-1/MAFbx mediated MyoD proteolysis prevents skeletal muscle atrophy in vivo Targeted expression of receptor-associated late transducer inhibits maladaptive hypertrophy via blocking epidermal growth factor receptor signaling Foxo3a inhibits cardiomyocyte hypertrophy through transactivating catalase PARP-inhibitor treatment prevents hypertension induced cardiac remodeling by favorable modulation of heat shock proteins, Akt-1/GSK-3β and several PKC isoforms.Functional redundancy of SWI/SNF catalytic subunits in maintaining vascular endothelial cells in the adult heart Muscle-specific RING finger 1 negatively regulates pathological cardiac hypertrophy through downregulation of calcineurin A.Sent to destroy: the ubiquitin proteasome system regulates cell signaling and protein quality control in cardiovascular development and disease.MAFbx/Atrogin-1 is required for atrophic remodeling of the unloaded heart.Oxidative stress: Biomarkers and novel therapeutic pathways.Atrogin-1 deficiency promotes cardiomyopathy and premature death via impaired autophagy.Deficiency of cardiac Acyl-CoA synthetase-1 induces diastolic dysfunction, but pathologic hypertrophy is reversed by rapamycin Autophagy and the ubiquitin-proteasome system in cardiac dysfunction.The "O" class: crafting clinical care with FoxO transcription factors.Influence of gestational overfeeding on cardiac morphometry and hypertrophic protein markers in fetal sheep The FoxO family in cardiac function and dysfunction.Cardiac muscle ring finger-1--friend or foe?Wnt1/βcatenin injury response activates the epicardium and cardiac fibroblasts to promote cardiac repair.Muscle atrophy in response to cytotoxic chemotherapy is dependent on intact glucocorticoid signaling in skeletal muscle.Ubiquitin-activating enzyme E1 inhibitor PYR41 attenuates angiotensin II-induced activation of dendritic cells via the IκBa/NF-κB and MKP1/ERK/STAT1 pathways.Perturbation of cullin deneddylation via conditional Csn8 ablation impairs the ubiquitin-proteasome system and causes cardiomyocyte necrosis and dilated cardiomyopathy in mice.Transcriptional effects of E3 ligase atrogin-1/MAFbx on apoptosis, hypertrophy and inflammation in neonatal rat cardiomyocytes.Tearin' up my heart: proteolysis in the cardiac sarcomere The ubiquitin ligase MuRF1 protects against cardiac ischemia/reperfusion injury by its proteasome-dependent degradation of phospho-c-Jun.NF-κB inhibition protects against tumor-induced cardiac atrophy in vivo.Roles of F-box proteins in cancer Diet and sex modify exercise and cardiac adaptation in the mouse Regulation of skeletal muscle growth by the IGF1-Akt/PKB pathway: insights from genetic models.Tear me down: role of calpain in the development of cardiac ventricular hypertrophy.Regulation of the calpain and ubiquitin-proteasome systems in a canine model of muscular dystrophy.Proteasome functional insufficiency in cardiac pathogenesis.

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P2860

Atrogin-1 inhibits Akt-dependent cardiac hypertrophy in mice via ubiquitin-dependent coactivation of Forkhead proteins.

http://www.wikidata.org/entity/Q36088932

description

2007 nî lūn-bûn

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Atrogin-1 inhibits Akt-depende ...... tivation of Forkhead proteins.

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Atrogin-1 inhibits Akt-depende ...... tivation of Forkhead proteins.

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Atrogin-1 inhibits Akt-depende ...... tivation of Forkhead proteins.

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Journal of Clinical Investigation

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Atrogin-1 inhibits Akt-depende ...... tivation of Forkhead proteins.

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Cam Patterson

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David J Glass

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Holly McDonough

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Hui-Hua Li

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Monte S Willis

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Nathaniel Miller

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Pamela Lockyer

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P2860

FOXO4 transcriptional activity is regulated by monoubiquitination and USP7/HAUSP

Acetylation of Foxo1 alters its DNA-binding ability and sensitivity to phosphorylation

Atrogin-1, a muscle-specific F-box protein highly expressed during muscle atrophy

A non-proteolytic role for ubiquitin in Tat-mediated transactivation of the HIV-1 promoter

CHIP is a U-box-dependent E3 ubiquitin ligase: identification of Hsc70 as a target for ubiquitylation

Mammalian SIRT1 represses forkhead transcription factors

Identification of ubiquitin ligases required for skeletal muscle atrophy

Regulation of cardiac hypertrophy by intracellular signalling pathways

Sensing of Lys 63-linked polyubiquitination by NEMO is a key event in NF-kappaB activation [corrected]

Foxo transcription factors induce the atrophy-related ubiquitin ligase atrogin-1 and cause skeletal muscle atrophy

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117

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17965779

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2040316

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