Altered phase diagram due to a single point mutation in human gammaD-crystallin. - Wikidata - awgldk - TriplyDB

Altered phase diagram due to a single point mutation in human gammaD-crystallin.

Altered phase diagram due to a single point mutation in human gammaD-crystallin.

http://www.wikidata.org/entity/Q36089188

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The Structure of the Cataract-Causing P23T Mutant of Human γD-Crystallin Exhibits Distinctive Local Conformational and Dynamic Changes † , ‡Single-shot real-time video recording of a photonic Mach cone induced by a scattered light pulse Cataract-associated P23T γD-crystallin retains a native-like fold in amorphous-looking aggregates formed at physiological pH.The congenital cataract-linked G61C mutation destabilizes γD-crystallin and promotes non-native aggregation Phase transitions in human IgG solutions.Coarse-grained model for colloidal protein interactions, B(22), and protein cluster formation.A single destabilizing mutation (F9S) promotes concerted unfolding of an entire globular domain in gammaS-crystallin.Phase behavior of mixtures of human lens proteins Gamma D and Beta B1.Role of anisotropic interactions for proteins and patchy nanoparticles.The molecular refractive function of lens γ-Crystallins.On the distribution of protein refractive index increments.The role of macromolecular crowding in the evolution of lens crystallins with high molecular refractive index.Crystalline cataract caused by a heterozygous missense mutation in γD-crystallin (CRYGD).Structural and biochemical characterization of the childhood cataract-associated R76S mutant of human γD-crystallin.The Effect of Attractive Interactions and Macromolecular Crowding on Crystallins Association.Protein anisotropy turns solubility on its head.Computational crystallization.Protein-protein interactions and lens transparency.Solution properties of γ-crystallins: hydration of fish and mammal γ-crystallins.Characterizing protein crystal contacts and their role in crystallization: rubredoxin as a case study.Increased hydrophobicity and decreased backbone flexibility explain the lower solubility of a cataract-linked mutant of γD-crystallin.Ion-activated attractive patches as a mechanism for controlled protein interactions.Modeling phase transitions in mixtures of β-γ lens crystallins.Structural and aggregation behavior of the human γD-crystallin mutant E107A, associated with congenital nuclear cataract Self-assembly of protein aggregates in ageing disorders: the lens and cataract model.Patterns of gene expression in microarrays and expressed sequence tags from normal and cataractous lenses NMR study of the cataract-linked P23T mutant of human gammaD-crystallin shows minor changes in hydrophobic patches that reflect its retrograde solubility.Increase in surface hydrophobicity of the cataract-associated P23T mutant of human gammaD-crystallin is responsible for its dramatically lower, retrograde solubility.Effect of the surface charge distribution on the fluid phase behavior of charged colloids and proteins.The stability of a crystal with diamond structure for patchy particles with tetrahedral symmetry.Effects of patch size and number within a simple model of patchy colloids.Model for screened, charge-regulated electrostatics of an eye lens protein: Bovine gammaB-crystallin.Crystallization of asymmetric patchy models for globular proteins in solution.Protein analysis by dynamic light scattering: methods and techniques for students.Phase diagram and structural properties of a simple model for one-patch particles.A simple patchy colloid model for the phase behavior of lysozyme dispersions.How fluorescent labelling alters the solution behaviour of proteins.Basis for calculating cross sections for nuclear magnetic resonance spin-modulated polarized neutron scattering.The self assembly of proteins; probing patchy protein interactions.Versatile procedure for site-specific grafting of polymer brushes on patchy particles via atom transfer radical polymerization (ATRP)

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P2860

Altered phase diagram due to a single point mutation in human gammaD-crystallin.

http://www.wikidata.org/entity/Q36089188

description

2007 nî lūn-bûn

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2007年论文

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name

Altered phase diagram due to a single point mutation in human gammaD-crystallin.

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Altered phase diagram due to a single point mutation in human gammaD-crystallin.

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type

label

Altered phase diagram due to a single point mutation in human gammaD-crystallin.

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Altered phase diagram due to a single point mutation in human gammaD-crystallin.

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prefLabel

Altered phase diagram due to a single point mutation in human gammaD-crystallin.

@ast

Altered phase diagram due to a single point mutation in human gammaD-crystallin.

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Proceedings of the National Academy of Sciences of the United States of America

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Altered phase diagram due to a single point mutation in human gammaD-crystallin.

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Ajay Pande

http://www.w3.org/2001/XMLSchema#string

Aleksey Lomakin

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George B Benedek

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Jayanti Pande

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Jennifer J McManus

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Markus Basan

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Olutayo Ogun

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P2860

Progressive juvenile-onset punctate cataracts caused by mutation of the gammaD-crystallin gene

Novel mutations in the gamma-crystallin genes cause autosomal dominant congenital cataracts

Cloning, expression, and chaperone-like activity of human alphaA-crystallin

The gamma-crystallins and human cataracts: a puzzle made clearer

Crystal cataracts: human genetic cataract caused by protein crystallization

Molecular basis of a progressive juvenile-onset hereditary cataract

Link between a novel human gammaD-crystallin allele and a unique cataract phenotype explained by protein crystallography

High-resolution X-ray crystal structures of human gammaD crystallin (1.25 A) and the R58H mutant (1.15 A) associated with aculeiform cataract

Aeolotopic interactions of globular proteins.

Liquid-liquid separation in solutions of normal and sickle cell hemoglobin.

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