Location of persisting mycobacteria in a Guinea pig model of tuberculosis revealed by r207910. - Wikidata - awgldk - TriplyDB

Location of persisting mycobacteria in a Guinea pig model of tuberculosis revealed by r207910.

Location of persisting mycobacteria in a Guinea pig model of tuberculosis revealed by r207910.

http://www.wikidata.org/entity/Q36094916

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Multiple M. tuberculosis phenotypes in mouse and guinea pig lung tissue revealed by a dual-staining approach The role of the novel exopolyphosphatase MT0516 in Mycobacterium tuberculosis drug tolerance and persistence Mathematical modeling of tuberculosis bacillary counts and cellular populations in the organs of infected mice.TMC207: the first compound of a new class of potent anti-tuberculosis drugs Heterogeneity in tuberculosis pathology, microenvironments and therapeutic responses A medicinal chemists' guide to the unique difficulties of lead optimization for tuberculosis Evidence for oxidative stress and defective antioxidant response in guinea pigs with tuberculosis Glycolytic and Non-glycolytic Functions of Mycobacterium tuberculosis Fructose-1,6-bisphosphate Aldolase, an Essential Enzyme Produced by Replicating and Non-replicating Bacilli Increased expression of host iron-binding proteins precedes iron accumulation and calcification of primary lung lesions in experimental tuberculosis in the guinea pig Location of intra- and extracellular M. tuberculosis populations in lungs of mice and guinea pigs during disease progression and after drug treatment Efficacy of Mycobacterium indicus pranii immunotherapy as an adjunct to chemotherapy for tuberculosis and underlying immune responses in the lung The Mycobacterium tuberculosis DosR regulon assists in metabolic homeostasis and enables rapid recovery from nonrespiring dormancy Pentacyclic nitrofurans with in vivo efficacy and activity against nonreplicating Mycobacterium tuberculosis Three-dimensional in vitro models of granuloma to study bacteria-host interactions, drug-susceptibility, and resuscitation of dormant mycobacteria Granuloma encapsulation is a key factor for containing tuberculosis infection in minipigs Tuberculous granulomas are hypoxic in guinea pigs, rabbits, and nonhuman primates Mycobacterial Cultures Contain Cell Size and Density Specific Sub-populations of Cells with Significant Differential Susceptibility to Antibiotics, Oxidative and Nitrite Stress Cytokine profiles in primary and secondary pulmonary granulomas of Guinea pigs with tuberculosis.Spectinamides are effective partner agents for the treatment of tuberculosis in multiple mouse infection models Comparison of the 'Denver regimen' against acute tuberculosis in the mouse and guinea pig.Evaluation of standard chemotherapy in the guinea pig model of tuberculosis A Review of the Evidence for Using Bedaquiline (TMC207) to Treat Multi-Drug Resistant Tuberculosis Interleukin-11 drives early lung inflammation during Mycobacterium tuberculosis infection in genetically susceptible mice.Low dose aerosol fitness at the innate phase of murine infection better predicts virulence amongst clinical strains of Mycobacterium tuberculosis The stringent response is required for full virulence of Mycobacterium tuberculosis in guinea pigs.Uptake and accumulation of oxidized low-density lipoprotein during Mycobacterium tuberculosis infection in guinea pigs.Latent tuberculosis infection: myths, models, and molecular mechanisms Activities of TMC207, rifampin, and pyrazinamide against Mycobacterium tuberculosis infection in guinea pigs.Long-acting antituberculous therapeutic nanoparticles target macrophage endosomes.A new recombinant BCG vaccine induces specific Th17 and Th1 effector cells with higher protective efficacy against tuberculosis.Dose-dependent activity of pyrazinamide in animal models of intracellular and extracellular tuberculosis infections.Contribution of the nitroimidazoles PA-824 and TBA-354 to the activity of novel regimens in murine models of tuberculosis.Impact of a low-oxygen environment on the efficacy of antimicrobials against intracellular Chlamydia trachomatis.bis-Molybdopterin guanine dinucleotide is required for persistence of Mycobacterium tuberculosis in guinea pigs.Effectiveness of tuberculosis chemotherapy correlates with resistance to Mycobacterium tuberculosis infection in animal models Development of new vaccines and drugs for TB: limitations and potential strategic errors Non-replicating Mycobacterium tuberculosis elicits a reduced infectivity profile with corresponding modifications to the cell wall and extracellular matrix.Post-exposure vaccination against Mycobacterium tuberculosis.The path of anti-tuberculosis drugs: from blood to lesions to mycobacterial cells.Expression of antimicrobial drug tolerance by attached communities of Mycobacterium tuberculosis.

P2860

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P2860

Location of persisting mycobacteria in a Guinea pig model of tuberculosis revealed by r207910.

http://www.wikidata.org/entity/Q36094916

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Location of persisting mycobac ...... erculosis revealed by r207910.

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Anne J Lenaerts

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Donald Hoff

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Ian M Orme

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Koen Andries

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Luis Cantarero

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Randall J Basaraba

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Sahar Aly

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Stefan Ehlers

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P2860

A small-molecule nitroimidazopyran drug candidate for the treatment of tuberculosis

Lessons from a proficiency testing event for acid-fast microscopy

An in vitro model for sequential study of shiftdown of Mycobacterium tuberculosis through two stages of nonreplicating persistence

Is adipose tissue a place for Mycobacterium tuberculosis persistence?

A diarylquinoline drug active on the ATP synthase of Mycobacterium tuberculosis

Mycobacterium avium genes associated with the ability to form a biofilm.

Replication dynamics of Mycobacterium tuberculosis in chronically infected mice

Designer arrays for defined mutant analysis to detect genes essential for survival of Mycobacterium tuberculosis in mouse lungs

Bactericidal activity of the nitroimidazopyran PA-824 in a murine model of tuberculosis.

Preclinical testing of the nitroimidazopyran PA-824 for activity against Mycobacterium tuberculosis in a series of in vitro and in vivo models.

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