Trio's Rho-specific GEF domain is the missing Galpha q effector in C. elegans - Wikidata - awgldk - TriplyDB

Trio's Rho-specific GEF domain is the missing Galpha q effector in C. elegans

Trio's Rho-specific GEF domain is the missing Galpha q effector in C. elegans

http://www.wikidata.org/entity/Q36098234

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p63RhoGEF: a new switch for G(q)-mediated activation of smooth muscle.Function and regulation of the Rho guanine nucleotide exchange factor Trio RHGF-2 is an essential Rho-1 specific RhoGEF that binds to the multi-PDZ domain scaffold protein MPZ-1 in Caenorhabditis elegans A novel molecular solution for ultraviolet light detection in Caenorhabditis elegans QuantWorm: a comprehensive software package for Caenorhabditis elegans phenotypic assays Behavioral and immune responses to infection require Gαq- RhoA signaling in C. elegans The RHO-1 RhoGTPase modulates fertility and multiple behaviors in adult C. elegans Kalrn plays key roles within and outside of the nervous system Strike a pose: Gαq complexes at the membrane TRPC Channels Mediate a Muscarinic Receptor-Induced Afterdepolarization in Cerebral Cortex.Profiling a Caenorhabditis elegans behavioral parametric dataset with a supervised K-means clustering algorithm identifies genetic networks regulating locomotion.An organelle gatekeeper function for Caenorhabditis elegans UNC-16 (JIP3) at the axon initial segment.Systematic profiling of Caenorhabditis elegans locomotive behaviors reveals additional components in G-protein Gαq signaling Structure and function of heterotrimeric G protein-regulated Rho guanine nucleotide exchange factors.Galpha q allosterically activates and relieves autoinhibition of p63RhoGEF.Systemic and cell intrinsic roles of Gqalpha signaling in the regulation of innate immunity, oxidative stress, and longevity in Caenorhabditis elegans.Trio, a Rho Family GEF, Interacts with the Presynaptic Active Zone Proteins Piccolo and Bassoon.Reduced sleep-like quiescence in both hyperactive and hypoactive mutants of the Galphaq Gene egl-30 during lethargus in Caenorhabditis elegans UNC-73/trio RhoGEF-2 activity modulates Caenorhabditis elegans motility through changes in neurotransmitter signaling upstream of the GSA-1/Galphas pathway.Recruitment of sphingosine kinase to presynaptic terminals by a conserved muscarinic signaling pathway promotes neurotransmitter release The small GTPase Rab2 functions in the removal of apoptotic cells in Caenorhabditis elegans.A genome-wide RNAi screen reveals a Trio-regulated Rho GTPase circuitry transducing mitogenic signals initiated by G protein-coupled receptors.Protein kinase C-related kinase and ROCK are required for thrombin-induced endothelial cell permeability downstream from Galpha12/13 and Galpha11/q.A neuronal signaling pathway of CaMKII and Gqα regulates experience-dependent transcription of tph-1.A functional siRNA screen identifies genes modulating angiotensin II-mediated EGFR transactivation.Impaired dense core vesicle maturation in Caenorhabditis elegans mutants lacking Rab2 Regulation and physiological functions of G12/13-mediated signaling pathways.Pharmacogenetic analysis reveals a post-developmental role for Rac GTPases in Caenorhabditis elegans GABAergic neurotransmission.Neuronal Rho GEFs in synaptic physiology and behavior.Synaptic plasticity, a symphony in GEF.Rho-guanine nucleotide exchange factors during development: Force is nothing without control.The many faces of the guanine-nucleotide exchange factor trio.Regulation, Signaling, and Physiological Functions of G-Proteins.Essential role for phosphatidylinositol 4,5-bisphosphate in the expression, regulation, and gating of the slow afterhyperpolarization current in the cerebral cortex.Neurotransmitter signaling through heterotrimeric G proteins: insights from studies in C. elegans.Reversal of salt preference is directed by the insulin/PI3K and Gq/PKC signaling in Caenorhabditis elegans.Assembly of high order G alpha q-effector complexes with RGS proteins.The SEK-1 p38 MAP Kinase Pathway Modulates Gq Signaling in Caenorhabditis elegans.Activity of the C. elegans egg-laying behavior circuit is controlled by competing activation and feedback inhibition Dopamine negatively modulates the NCA ion channels in C. elegans.

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Trio's Rho-specific GEF domain is the missing Galpha q effector in C. elegans

http://www.wikidata.org/entity/Q36098234

description

2007 nî lūn-bûn

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2007年の論文

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2007年論文

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2007年論文

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2007年論文

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2007年論文

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2007年論文

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2007年论文

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2007年论文

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2007年论文

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name

Trio's Rho-specific GEF domain is the missing Galpha q effector in C. elegans

@ast

Trio's Rho-specific GEF domain is the missing Galpha q effector in C. elegans

@en

type

label

Trio's Rho-specific GEF domain is the missing Galpha q effector in C. elegans

@ast

Trio's Rho-specific GEF domain is the missing Galpha q effector in C. elegans

@en

prefLabel

Trio's Rho-specific GEF domain is the missing Galpha q effector in C. elegans

@ast

Trio's Rho-specific GEF domain is the missing Galpha q effector in C. elegans

@en

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Genes & Development

P1476

Trio's Rho-specific GEF domain is the missing Galpha q effector in C. elegans

@en

P2093

Cassandra Coco

http://www.w3.org/2001/XMLSchema#string

Christiane Vettel

http://www.w3.org/2001/XMLSchema#string

Erik M Jorgensen

http://www.w3.org/2001/XMLSchema#string

Kenneth G Miller

http://www.w3.org/2001/XMLSchema#string

Michael Ailion

http://www.w3.org/2001/XMLSchema#string

Nicole K Charlie

http://www.w3.org/2001/XMLSchema#string

Stacey L Williams

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Susanne Lutz

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P2860

Sea Anemone Genome Reveals Ancestral Eumetazoan Gene Repertoire and Genomic Organization

beta-Arrestin 1 and Galphaq/11 coordinately activate RhoA and stress fiber formation following receptor stimulation

Galphaq directly activates p63RhoGEF and Trio via a conserved extension of the Dbl homology-associated pleckstrin homology domain

Rapid single nucleotide polymorphism mapping in C. elegans

Structure of Galphaq-p63RhoGEF-RhoA complex reveals a pathway for the activation of RhoA by GPCRs

Regulation of polyphosphoinositide-specific phospholipase C activity by purified Gq.

Characterization of G-protein alpha subunits in the Gq class: expression in murine tissues and in stromal and hematopoietic cell lines

p63RhoGEF and GEFT are Rho-specific guanine nucleotide exchange factors encoded by the same gene

EGL-10 regulates G protein signaling in the C. elegans nervous system and shares a conserved domain with many mammalian proteins

Direct stimulation of the guanine nucleotide exchange activity of p115 RhoGEF by Galpha13

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2731-2746

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10.1101/GAD.1592007

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21

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21

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2007-10-17T00:00:00Z

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5902342

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17942708

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Caenorhabditis elegans

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2045128

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