Emerin is hyperphosphorylated and redistributed in herpes simplex virus type 1-infected cells in a manner dependent on both UL34 and US3. - Wikidata - awgldk - TriplyDB

Emerin is hyperphosphorylated and redistributed in herpes simplex virus type 1-infected cells in a manner dependent on both UL34 and US3.

Emerin is hyperphosphorylated and redistributed in herpes simplex virus type 1-infected cells in a manner dependent on both UL34 and US3.

http://www.wikidata.org/entity/Q36099092

about

The nuclear envelope LEM-domain protein emerin Herpesviruses and intermediate filaments: close encounters with the third type Cyclin-dependent kinase-like function is shared by the beta- and gamma- subset of the conserved herpesvirus protein kinases O-Linked β-N-acetylglucosamine (O-GlcNAc) regulates emerin binding to barrier to autointegration factor (BAF) in a chromatin- and lamin B-enriched "niche".Nuclear egress and envelopment of herpes simplex virus capsids analyzed with dual-color fluorescence HSV1(17+)Viral mimicry of Cdc2/cyclin-dependent kinase 1 mediates disruption of nuclear lamina during human cytomegalovirus nuclear egress.Effects of phosphorylation of herpes simplex virus 1 envelope glycoprotein B by Us3 kinase in vivo and in vitro Constitutive mTORC1 activation by a herpesvirus Akt surrogate stimulates mRNA translation and viral replication New role for EMD (emerin), a key inner nuclear membrane protein, as an enhancer of autophagosome formation in the C16-ceramide autophagy pathway p32 is a novel target for viral protein ICP34.5 of herpes simplex virus type 1 and facilitates viral nuclear egress.Us3 kinase encoded by herpes simplex virus 1 mediates downregulation of cell surface major histocompatibility complex class I and evasion of CD8+ T cells Herpes simplex virus 1 protein kinase Us3 and major tegument protein UL47 reciprocally regulate their subcellular localization in infected cells.Emerin in health and disease.The UL13 and US3 Protein Kinases of Herpes Simplex Virus 1 Cooperate to Promote the Assembly and Release of Mature, Infectious Virions.An Intracellular Arrangement of Histoplasma capsulatum Yeast-Aggregates Generates Nuclear Damage to the Cultured Murine Alveolar Macrophages.Identification of a physiological phosphorylation site of the herpes simplex virus 1-encoded protein kinase Us3 which regulates its optimal catalytic activity in vitro and influences its function in infected cells.Effects of lamin A/C, lamin B1, and viral US3 kinase activity on viral infectivity, virion egress, and the targeting of herpes simplex virus U(L)34-encoded protein to the inner nuclear membrane Nuclear pore composition and gating in herpes simplex virus-infected cells Two viral kinases are required for sustained long distance axon transport of a neuroinvasive herpesvirus.Herpesvirus gB-induced fusion between the virion envelope and outer nuclear membrane during virus egress is regulated by the viral US3 kinase.Regulation of the catalytic activity of herpes simplex virus 1 protein kinase Us3 by autophosphorylation and its role in pathogenesis.Phosphorylation of the U(L)31 protein of herpes simplex virus 1 by the U(S)3-encoded kinase regulates localization of the nuclear envelopment complex and egress of nucleocapsids.Nuclear Exodus: Herpesviruses Lead the Way.Herpes Simplex Virus 1 Induces Phosphorylation and Reorganization of Lamin A/C through the γ134.5 Protein That Facilitates Nuclear Egress Differences in the regulatory and functional effects of the Us3 protein kinase activities of herpes simplex virus 1 and 2.Herpes simplex virus 1 protein kinase Us3 phosphorylates viral dUTPase and regulates its catalytic activity in infected cells.Varicella-zoster virus open reading frame 66 protein kinase and its relationship to alphaherpesvirus US3 kinases.Phosphorylation of a herpes simplex virus 1 dUTPase by a viral protein kinase, Us3, dictates viral pathogenicity in the central nervous system but not at the periphery.Viral serine/threonine protein kinases Role of tegument proteins in herpesvirus assembly and egress.Herpesviruses remodel host membranes for virus egress.Breach of the nuclear lamina during assembly of herpes simplex viruses.Nuclear actin and lamins in viral infections.Nucleolin is required for efficient nuclear egress of herpes simplex virus type 1 nucleocapsids.A functional role for TorsinA in herpes simplex virus 1 nuclear egress.Intragenic and extragenic suppression of a mutation in herpes simplex virus 1 UL34 that affects both nuclear envelope targeting and membrane budding.Nuclear envelope breakdown induced by herpes simplex virus type 1 involves the activity of viral fusion proteins.Diseases of the Nucleoskeleton.Characterization of conserved region 2-deficient mutants of the cytomegalovirus egress protein pM53.Herpes simplex virus 1 pUL34 plays a critical role in cell-to-cell spread of virus in addition to its role in virus replication

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P2860

Emerin is hyperphosphorylated and redistributed in herpes simplex virus type 1-infected cells in a manner dependent on both UL34 and US3.

http://www.wikidata.org/entity/Q36099092

description

2007 nî lūn-bûn

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2007年の論文

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2007年論文

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2007年論文

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2007年論文

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2007年論文

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2007年論文

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2007年论文

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2007年论文

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2007年论文

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name

Emerin is hyperphosphorylated ...... ependent on both UL34 and US3.

@ast

Emerin is hyperphosphorylated ...... ependent on both UL34 and US3.

@en

type

label

Emerin is hyperphosphorylated ...... ependent on both UL34 and US3.

@ast

Emerin is hyperphosphorylated ...... ependent on both UL34 and US3.

@en

prefLabel

Emerin is hyperphosphorylated ...... ependent on both UL34 and US3.

@ast

Emerin is hyperphosphorylated ...... ependent on both UL34 and US3.

@en

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P1433

Journal of Virology

P1476

Emerin is hyperphosphorylated ...... ependent on both UL34 and US3.

@en

P2093

Desire K Christensen

http://www.w3.org/2001/XMLSchema#string

Fan Mou

http://www.w3.org/2001/XMLSchema#string

Jacques M Bouchard

http://www.w3.org/2001/XMLSchema#string

Joel Baines

http://www.w3.org/2001/XMLSchema#string

Natalie Leach

http://www.w3.org/2001/XMLSchema#string

Richard J Roller

http://www.w3.org/2001/XMLSchema#string

Richard Park

http://www.w3.org/2001/XMLSchema#string

Susan L Bjerke

http://www.w3.org/2001/XMLSchema#string

Tokuko Haraguchi

http://www.w3.org/2001/XMLSchema#string

P2860

MAN1, an inner nuclear membrane protein that shares the LEM domain with lamina-associated polypeptide 2 and emerin

Conformational changes in the nuclear lamina induced by herpes simplex virus type 1 require genes U(L)31 and U(L)34

Emerin caps the pointed end of actin filaments: evidence for an actin cortical network at the nuclear inner membrane

Emerin binding to Btf, a death-promoting transcriptional repressor, is disrupted by a missense mutation that causes Emery-Dreifuss muscular dystrophy

Identification of a novel X-linked gene responsible for Emery-Dreifuss muscular dystrophy

Roscovitine, a specific inhibitor of cellular cyclin-dependent kinases, inhibits herpes simplex virus DNA synthesis in the presence of viral early proteins

Detergent-salt resistance of LAP2alpha in interphase nuclei and phosphorylation-dependent association with chromosomes early in nuclear assembly implies functions in nuclear structure dynamics.

Roscovitine inhibits activation of promoters in herpes simplex virus type 1 genomes independently of promoter-specific factors

Direct interaction between emerin and lamin A

Regulation of cell apoptosis by protein kinase c delta

P304

10792-10803

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scholarly article

P356

10.1128/JVI.00196-07

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P407

P433

19

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P478

81

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2007-07-25T00:00:00Z

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17652388

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2045475

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