Reversal of diet-induced obesity and insulin resistance by inducible genetic ablation of GRK2.
about
Insulin Signaling and Heart Failure.GRK2 compromises cardiomyocyte mitochondrial function by diminishing fatty acid-mediated oxygen consumption and increasing superoxide levelsTargeting GPCR-Gβγ-GRK2 signaling as a novel strategy for treating cardiorenal pathologies.Insulin and β Adrenergic Receptor Signaling: Crosstalk in Heart.Cross-Talk Between Insulin Signaling and G Protein-Coupled Receptors.Obesity-induced cardiac lipid accumulation in adult mice is modulated by G protein-coupled receptor kinase 2 levels.Suppression of GRK2 expression reduces endothelial dysfunction by restoring glucose homeostasis.Loss of FTO in adipose tissue decreases Angptl4 translation and alters triglyceride metabolism.GRK2 as a therapeutic target for heart failure.Inhibiting Insulin-Mediated β2-Adrenergic Receptor Activation Prevents Diabetes-Associated Cardiac Dysfunction.Stevioside modulates oxidative damage in the liver and kidney of high fat/low streptozocin diabetic rats.New Insights in Cardiac β-Adrenergic Signaling During Heart Failure and Aging
P2860
Q30377910-F925480A-AD03-4A57-ACB2-1D500B8A8B06Q36399800-C35E9435-829F-4A95-B8EA-F7307B230564Q39107039-A3B402A0-7439-4180-94E7-9B0B72CE4547Q39159635-FC0307EC-6BD4-4C37-88C9-3EA2A32BAA4AQ39193265-F2340972-404A-4396-8198-3FAE5B7A8509Q39198039-4612ED69-9E38-47EA-AECB-E4779FC0A3AAQ41436367-A04D3643-F482-49F4-8FC2-251126559750Q42816802-1B174489-2AE6-422D-9EB8-7DBDA518529DQ45874891-1573702E-B565-4CC7-81FE-5D8B03A9EEC3Q46138106-A0902F46-6C61-4CCE-BEB5-75556E21779FQ54976913-7A7D7FA5-7DC5-4515-ADED-D26613401376Q58790122-949B3520-204F-4308-814D-4742E3D8A357
P2860
Reversal of diet-induced obesity and insulin resistance by inducible genetic ablation of GRK2.
description
2015 nî lūn-bûn
@nan
2015年の論文
@ja
2015年論文
@yue
2015年論文
@zh-hant
2015年論文
@zh-hk
2015年論文
@zh-mo
2015年論文
@zh-tw
2015年论文
@wuu
2015年论文
@zh
2015年论文
@zh-cn
name
Reversal of diet-induced obesi ...... ible genetic ablation of GRK2.
@ast
Reversal of diet-induced obesi ...... ible genetic ablation of GRK2.
@en
type
label
Reversal of diet-induced obesi ...... ible genetic ablation of GRK2.
@ast
Reversal of diet-induced obesi ...... ible genetic ablation of GRK2.
@en
prefLabel
Reversal of diet-induced obesi ...... ible genetic ablation of GRK2.
@ast
Reversal of diet-induced obesi ...... ible genetic ablation of GRK2.
@en
P2093
P2860
P1433
P1476
Reversal of diet-induced obesi ...... ible genetic ablation of GRK2.
@en
P2093
Annemieke Kavelaars
Cobi J Heijnen
Cristina Murga
Elisa Lucas
Federico Mayor
Hanneke L D M Willemen
Marta Cruces-Sande
P2860
P356
10.1126/SCISIGNAL.AAA4374
P577
2015-07-21T00:00:00Z