Two isoforms of HOXA9 function differently but work synergistically in human MLL-rearranged leukemia.

about

Oncogene- and drug resistance-associated alternative exon usage in acute myeloid leukemia (AML).How mRNA is misspliced in acute myelogenous leukemia (AML)?The leukemogenicity of Hoxa9 depends on alternative splicing.

P2860

Q36771977-66827027-FD45-4388-88DB-71C53F15F871 Q38265600-3376E2C9-55FE-46A0-890B-5C7D36278291 Q44517584-95FEDE3B-C9EF-4B84-B6B2-5FE1EB2D435E

P2860

Two isoforms of HOXA9 function differently but work synergistically in human MLL-rearranged leukemia.

Item

http://www.wikidata.org/entity/Q36101066

description

2012 nî lūn-bûn

@nan

2012年の論文

@ja

2012年論文

@yue

2012年論文

@zh-hant

2012年論文

@zh-hk

2012年論文

@zh-mo

2012年論文

@zh-tw

2012年论文

@wuu

2012年论文

@zh

2012年论文

@zh-cn

name

Two isoforms of HOXA9 function ...... human MLL-rearranged leukemia.

@ast

Two isoforms of HOXA9 function ...... human MLL-rearranged leukemia.

@en

type

Item

label

Two isoforms of HOXA9 function ...... human MLL-rearranged leukemia.

@ast

Two isoforms of HOXA9 function ...... human MLL-rearranged leukemia.

@en

prefLabel

Two isoforms of HOXA9 function ...... human MLL-rearranged leukemia.

@ast

Two isoforms of HOXA9 function ...... human MLL-rearranged leukemia.

@en

P1476

Two isoforms of HOXA9 function ...... human MLL-rearranged leukemia.

@en

P2093

Hao Huang

http://www.w3.org/2001/XMLSchema#string

Janet D Rowley

http://www.w3.org/2001/XMLSchema#string

Jianjun Chen

http://www.w3.org/2001/XMLSchema#string

Mary Beth Neilly

http://www.w3.org/2001/XMLSchema#string

Miao He

http://www.w3.org/2001/XMLSchema#string

Minjie Wei

http://www.w3.org/2001/XMLSchema#string

Ping Chen

http://www.w3.org/2001/XMLSchema#string

Stephen Arnovitz

http://www.w3.org/2001/XMLSchema#string

Yuanyuan Li

http://www.w3.org/2001/XMLSchema#string

Zejuan Li

http://www.w3.org/2001/XMLSchema#string

P2860

Hoxa9 and Meis1 are key targets for MLL-ENL-mediated cellular immortalization

Identification and characterization of Hoxa9 binding sites in hematopoietic cells

Aberrant overexpression and function of the miR-17-92 cluster in MLL-rearranged acute leukemia

Loss of expression of the Hoxa-9 homeobox gene impairs the proliferation and repopulating ability of hematopoietic stem cells

A microRNA polycistron as a potential human oncogene

A naturally occurring isoform of the human macrophage scavenger receptor (SR-A) gene generated by alternative splicing blocks modified LDL uptake

Pbx proteins display hexapeptide-dependent cooperative DNA binding with a subset of Hox proteins

A conserved non-homeodomain Hoxa9 isoform interacting with CBP is co-expressed with the 'typical' Hoxa9 protein during embryogenesis

Hoxa9 transforms primary bone marrow cells through specific collaboration with Meis1a but not Pbx1b.

Hoxa9 immortalizes a granulocyte-macrophage colony-stimulating factor-dependent promyelocyte capable of biphenotypic differentiation to neutrophils or macrophages, independent of enforced meis expression.

P304

102-106

http://www.w3.org/2001/XMLSchema#string

P31

scholarly article

P356

10.1016/J.BCMD.2012.05.003

http://www.w3.org/2001/XMLSchema#string

P433

http://www.w3.org/2001/XMLSchema#string

P478

http://www.w3.org/2001/XMLSchema#string

P577

2012-05-25T00:00:00Z

http://www.w3.org/2001/XMLSchema#dateTime

P698

22633751

http://www.w3.org/2001/XMLSchema#string

P932

3399022

http://www.w3.org/2001/XMLSchema#string

Two isoforms of HOXA9 function differently but work synergistically in human MLL-rearranged leukemia.

about

P2860

P2860

Two isoforms of HOXA9 function differently but work synergistically in human MLL-rearranged leukemia.

description

name

type

label

prefLabel

P1433

P1476

P2093

P2860

P304

P31

P356

P433

P478

P577

P698

P932

P356

P1433

P1476

P2093

P2860

P304

P31

P356

P433

P478

P577

P698

P932