The pathogenesis of chronic obstructive pulmonary disease: advances in the past 100 years.
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Chronic obstructive pulmonary diseaseX-ray Snapshot of the Mechanism of Inactivation of Human Neutrophil Elastase by 1,2,5-Thiadiazolidin-3-one 1,1-Dioxide Derivatives †Neutrophil elastase-initiated EGFR/MEK/ERK signaling counteracts stabilizing effect of autocrine TGF-beta on tropoelastin mRNA in lung fibroblastsEGF antagonizes TGF-beta-induced tropoelastin expression in lung fibroblasts via stabilization of Smad corepressor TGIFFolliculin controls lung alveolar enlargement and epithelial cell survival through E-cadherin, LKB1, and AMPK.Integrative analysis of DNA methylation and gene expression data identifies EPAS1 as a key regulator of COPD.Cigarette smoke drives small airway remodeling by induction of growth factors in the airway wall.Mitochondrial localization and function of heme oxygenase-1 in cigarette smoke-induced cell death.Utilization of the 1,2,3,5-thiatriazolidin-3-one 1,1-dioxide scaffold in the design of potential inhibitors of human neutrophil proteinase 3.A microRNA processing defect in smokers' macrophages is linked to SUMOylation of the endonuclease DICERSenescent cells: a novel therapeutic target for aging and age-related diseasesMechanism-based inhibitors of serine proteases with high selectivity through optimization of S' subsite binding.Alveolar macrophage recruitment and activation by chronic second hand smoke exposure in mice.Biologic phenotyping of the human small airway epithelial response to cigarette smoking.Inhibitors of human neutrophil elastase based on a highly functionalized N-amino-4-imidazolidinone scaffoldEffects of structure on inhibitory activity in a series of mechanism-based inhibitors of human neutrophil elastase.Cigarette smoking decreases global microRNA expression in human alveolar macrophages.Airway mucus obstruction triggers macrophage activation and matrix metalloproteinase 12-dependent emphysema.FRET-based and other fluorescent proteinase probes.c-Kit is essential for alveolar maintenance and protection from emphysema-like disease in mice.Electronic health records and improved nursing management of chronic obstructive pulmonary disease.Inflammation and pathological damage to the lungs of mice are only partially reversed following smoking cessation on subacute exposure to cigarette smoke.Tropoelastin modulates TGF-β1-induced expression of VEGF and CTGF in airway smooth muscle cells.Smoking and idiopathic pulmonary fibrosisCoordinated changes in AHRR methylation in lymphoblasts and pulmonary macrophages from smokers.Role of neutrophil elastase in LTB4-induced neutrophil transmigration in vivo assessed with a specific inhibitor and neutrophil elastase deficient miceSquamous metaplasia amplifies pathologic epithelial-mesenchymal interactions in COPD patients.Biomarkers in Exhaled Breath Condensate and Serum of Chronic Obstructive Pulmonary Disease and Non-Small-Cell Lung Cancer.Tristetraprolin Down-Regulation Contributes to Persistent TNF-Alpha Expression Induced by Cigarette Smoke Extract through a Post-Transcriptional MechanismRole of infection and antimicrobial therapy in acute exacerbations of chronic obstructive pulmonary disease.Bronchial epithelial spheroids: an alternative culture model to investigate epithelium inflammation-mediated COPD.Update in chronic obstructive pulmonary disease 2005.Respiratory infection and the impact of pulmonary immunity on lung health and diseaseInactivation of human neutrophil elastase by 1,2,5-thiadiazolidin-3-one 1,1 dioxide-based sulfonamidesAdvances in the pathology of COPD.Multiple roles of phospholipase A2 during lung infection and inflammation.Adverse Outcomes Associated with Cigarette Smoke Radicals Related to Damage to Protein-disulfide IsomeraseVariability in small airway epithelial gene expression among normal smokers.Outpatient pulmonary rehabilitation in patients with chronic obstructive pulmonary diseaseDecline in NRF2-regulated antioxidants in chronic obstructive pulmonary disease lungs due to loss of its positive regulator, DJ-1
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P2860
The pathogenesis of chronic obstructive pulmonary disease: advances in the past 100 years.
description
2005 nî lūn-bûn
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2005年の論文
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2005年論文
@yue
2005年論文
@zh-hant
2005年論文
@zh-hk
2005年論文
@zh-mo
2005年論文
@zh-tw
2005年论文
@wuu
2005年论文
@zh
2005年论文
@zh-cn
name
The pathogenesis of chronic ob ...... dvances in the past 100 years.
@ast
The pathogenesis of chronic ob ...... dvances in the past 100 years.
@en
type
label
The pathogenesis of chronic ob ...... dvances in the past 100 years.
@ast
The pathogenesis of chronic ob ...... dvances in the past 100 years.
@en
prefLabel
The pathogenesis of chronic ob ...... dvances in the past 100 years.
@ast
The pathogenesis of chronic ob ...... dvances in the past 100 years.
@en
P2860
P356
P1476
The pathogenesis of chronic ob ...... dvances in the past 100 years.
@en
P2093
Edward P Ingenito
Steven D Shapiro
P2860
P304
P356
10.1165/RCMB.F296
P577
2005-05-01T00:00:00Z