The chemopreventive agent curcumin is a potent radiosensitizer of human cervical tumor cells via increased reactive oxygen species production and overactivation of the mitogen-activated protein kinase pathway.
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Relationship and interactions of curcumin with radiation therapyCurcumin-the paradigm of a multi-target natural compound with applications in cancer prevention and treatmentMitochondrial-targeted curcuminoids: a strategy to enhance bioavailability and anticancer efficacy of curcuminThioredoxin reductase-1 mediates curcumin-induced radiosensitization of squamous carcinoma cellsDietary curcumin increases antioxidant defenses in lung, ameliorates radiation-induced pulmonary fibrosis, and improves survival in mice.Cervical cancer stem cells manifest radioresistance: Association with upregulated AP-1 activity.Curcumin induces chemo/radio-sensitization in ovarian cancer cells and curcumin nanoparticles inhibit ovarian cancer cell growth.Berberine radiosensitizes human esophageal cancer cells by downregulating homologous recombination repair protein RAD51Distinct combinatorial effects of the plant polyphenols curcumin, carnosic acid, and silibinin on proliferation and apoptosis in acute myeloid leukemia cells.Cyclooxygenase-1 and -2: molecular targets for cervical neoplasia.Curcumin for radiation dermatitis: a randomized, double-blind, placebo-controlled clinical trial of thirty breast cancer patients.Involvement of ROS in Curcumin-induced Autophagic Cell DeathCurcumin regulates low-linear energy transfer γ-radiation-induced NFκB-dependent telomerase activity in human neuroblastoma cellsPhenylpropanoids in radioregulation: double edged sword.Agaricus blazei Extract Induces Apoptosis through ROS-Dependent JNK Activation Involving the Mitochondrial Pathway and Suppression of Constitutive NF-κB in THP-1 CellsCurcumin mitigates accelerated aging after irradiation in Drosophila by reducing oxidative stress.Discovery of curcumin, a component of golden spice, and its miraculous biological activities.Curcumin-loaded magnetic nanoparticles for breast cancer therapeutics and imaging applications.The chemopreventive and clinically used agent curcumin sensitizes HPV (-) but not HPV (+) HNSCC to ionizing radiation, in vitro and in a mouse orthotopic model.Small molecule tolfenamic acid and dietary spice curcumin treatment enhances antiproliferative effect in pancreatic cancer cells via suppressing Sp1, disrupting NF-kB translocation to nucleus and cell cycle phase distributionMiR-593 mediates curcumin-induced radiosensitization of nasopharyngeal carcinoma cells via MDR1New perspectives of curcumin in cancer prevention.Clinical development of novel proteasome inhibitors for cancer treatment.Curcumin and cancer cells: how many ways can curry kill tumor cells selectively?Curcumin enhances paraquat-induced apoptosis of N27 mesencephalic cells via the generation of reactive oxygen species.Curcumin potentiates antitumor activity of cisplatin in bladder cancer cell lines via ROS-mediated activation of ERK1/2.Activation of the CRABPII/RAR pathway by curcumin induces retinoic acid mediated apoptosis in retinoic acid resistant breast cancer cells.Characterization of a novel curcumin analog P1 as potent inhibitor of the NF-κB signaling pathway with distinct mechanisms.Curcumin, the golden spice from Indian saffron, is a chemosensitizer and radiosensitizer for tumors and chemoprotector and radioprotector for normal organs.Plant natural products: from traditional compounds to new emerging drugs in cancer therapy.Antiproliferative activity of Haematoxylum brasiletto H. Karst.Emerging importance of dietary phytochemicals in fight against cancer: Role in targeting cancer stem cells.Potentiality of syringetin for preferential radiosensitization to cancer cells.Thymoquinone restores radiation-induced TGF-β expression and abrogates EMT in chemoradiotherapy of breast cancer cells.Curcumin as a multifaceted compound against human papilloma virus infection and cervical cancers: A review of chemistry, cellular, molecular, and preclinical features.Curcumin induces apoptosis in human gastric carcinoma AGS cells and colon carcinoma HT-29 cells through mitochondrial dysfunction and endoplasmic reticulum stress.Energy deprivation by silibinin in colorectal cancer cells: a double-edged sword targeting both apoptotic and autophagic machineries.2,4-bis (p-hydroxyphenyl)-2-butenal (HPB242) induces apoptosis via modulating E7 expression and inhibition of PI3K/Akt pathway in SiHa human cervical cancer cells.Properties of lewis lung carcinoma cells surviving curcumin toxicityA synthetic compound, 1,5-bis(2-methoxyphenyl)penta-1,4-dien-3-one (B63), induces apoptosis and activates endoplasmic reticulum stress in non-small cell lung cancer cells.
P2860
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P2860
The chemopreventive agent curcumin is a potent radiosensitizer of human cervical tumor cells via increased reactive oxygen species production and overactivation of the mitogen-activated protein kinase pathway.
description
2008 nî lūn-bûn
@nan
2008年の論文
@ja
2008年論文
@yue
2008年論文
@zh-hant
2008年論文
@zh-hk
2008年論文
@zh-mo
2008年論文
@zh-tw
2008年论文
@wuu
2008年论文
@zh
2008年论文
@zh-cn
name
The chemopreventive agent curc ...... ivated protein kinase pathway.
@ast
The chemopreventive agent curc ...... ivated protein kinase pathway.
@en
type
label
The chemopreventive agent curc ...... ivated protein kinase pathway.
@ast
The chemopreventive agent curc ...... ivated protein kinase pathway.
@en
prefLabel
The chemopreventive agent curc ...... ivated protein kinase pathway.
@ast
The chemopreventive agent curc ...... ivated protein kinase pathway.
@en
P2093
P2860
P356
P1476
The chemopreventive agent curc ...... ivated protein kinase pathway.
@en
P2093
Andrew T Segan
Constantinos Koumenis
Prashanthi Javvadi
Stephen W Tuttle
P2860
P304
P356
10.1124/MOL.107.043554
P577
2008-02-05T00:00:00Z