The Set3 Complex Antagonizes the MYST Acetyltransferase Esa1 in the DNA Damage Response.

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upSET, the Drosophila homologue of SET3, Is Required for Viability and the Proper Balance of Active and Repressive Chromatin Marks.

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Q37629337-B8F2712F-78C4-4E66-9463-60C081FFA591

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The Set3 Complex Antagonizes the MYST Acetyltransferase Esa1 in the DNA Damage Response.

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The Set3 Complex Antagonizes the MYST Acetyltransferase Esa1 in the DNA Damage Response.

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The Set3 Complex Antagonizes the MYST Acetyltransferase Esa1 in the DNA Damage Response.

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The Set3 Complex Antagonizes the MYST Acetyltransferase Esa1 in the DNA Damage Response.

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The Set3 Complex Antagonizes the MYST Acetyltransferase Esa1 in the DNA Damage Response.

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The Set3 Complex Antagonizes the MYST Acetyltransferase Esa1 in the DNA Damage Response.

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The Set3 Complex Antagonizes the MYST Acetyltransferase Esa1 in the DNA Damage Response.

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P1476

The Set3 Complex Antagonizes the MYST Acetyltransferase Esa1 in the DNA Damage Response.

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Christie S Chang

http://www.w3.org/2001/XMLSchema#string

Lauren G Clark

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Lorraine Pillus

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P2860

Methyl methanesulfonate (MMS) produces heat-labile DNA damage but no detectable in vivo DNA double-strand breaks.

The language of covalent histone modifications

The S. cerevisiae SET3 complex includes two histone deacetylases, Hos2 and Hst1, and is a meiotic-specific repressor of the sporulation gene program.

A phylogenetically conserved NAD+-dependent protein deacetylase activity in the Sir2 protein family.

Histone deacetylases RPD3 and HOS2 regulate the transcriptional activation of DNA damage-inducible genes.

Stable incorporation of sequence specific repressors Ash1 and Ume6 into the Rpd3L complex.

Esa1p is an essential histone acetyltransferase required for cell cycle progression.

Distinct roles for the essential MYST family HAT Esa1p in transcriptional silencing.

Acetylation of histone H4 by Esa1 is required for DNA double-strand break repair.

A moonlighting metabolic protein influences repair at DNA double-stranded breaks.

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3714-3725

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scholarly article

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10.1128/MCB.00298-15

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English

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Ana Lilia Torres-Machorro

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2015-08-24T00:00:00Z

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26303527

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DNA damage

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4589593

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The Set3 Complex Antagonizes the MYST Acetyltransferase Esa1 in the DNA Damage Response.

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The Set3 Complex Antagonizes the MYST Acetyltransferase Esa1 in the DNA Damage Response.

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P1433

P1476

P2093

P2860

P304

P31

P356

P407

P433

P478

P50

P577

P698

P921

P932

P356

P1433

P1476

P2093

P2860

P304

P31

P356

P407

P433

P478

P50

P577

P698

P921

P932