Clonal analysis in recurrent astrocytic, oligoastrocytic and oligodendroglial tumors implicates IDH1- mutation as common tumor initiating event.
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IDH1/2 mutations target a key hallmark of cancer by deregulating cellular metabolism in gliomaIDH1 and IDH2 mutations as novel therapeutic targets: current perspectivesMolecular Markers in Low-Grade Glioma-Toward Tumor ReclassificationDeep sequencing of multiple regions of glial tumors reveals spatial heterogeneity for mutations in clinically relevant genesGenetic and epigenetic alterations in primary-progressive paired oligodendroglial tumors.Mutation analysis of IDH1 in paired gliomas revealed IDH1 mutation was not associated with malignant progression but predicted longer survivalIDH mutation status and role of WHO grade and mitotic index in overall survival in grade II-III diffuse gliomas.IDH1/2 mutation status combined with Ki-67 labeling index defines distinct prognostic groups in glioma.Primary and recurrent diffuse astrocytomas: genomic profile comparison reveals acquisition of biologically relevant aberrationsWhat do we know about IDH1/2 mutations so far, and how do we use it?PLK1 inhibition enhances temozolomide efficacy in IDH1 mutant gliomas.Paediatric and adult glioblastoma: multiform (epi)genomic culprits emerge.Isocitrate dehydrogenase 1 and 2 mutations in gliomas.Pathology and genetics of diffuse gliomas in adults.Emerging circulating biomarkers in glioblastoma: promises and challenges.Glioblastoma targeted therapy: updated approaches from recent biological insights.Non-canonical IDH1 and IDH2 mutations: a clonal and relevant event in an Italian cohort of gliomas classified according to the 2016 World Health Organization (WHO) criteria.Evolving Molecular Genetics of Glioblastoma.IDH mutations in cancer and progress toward development of targeted therapeutics.The new WHO 2016 classification of brain tumors-what neurosurgeons need to know.Isocitrate dehydrogenases in physiology and cancer: biochemical and molecular insight.IDH1 R132H Mutation Is Accompanied with Malignant Progression of Paired Primary-Recurrent Astrocytic TumoursPrimary Astrocytic Tumours and Paired Recurrences have Similar Biological Features in IDH1, TP53 and TERTp Mutation and MGMT, ATRX Loss.Farewell to oligoastrocytoma: in situ molecular genetics favor classification as either oligodendroglioma or astrocytoma.Protein Phosphatase Magnesium-Dependent 1δ (PPM1D) Expression as a Prognostic Marker in Adult Supratentorial Diffuse Astrocytic and Oligodenroglial Tumors.Analysis of CIC-associated CpG island methylation in oligoastrocytoma.Adapting the drivers to the road: a new strategy for cancer evolution?Clinical utility and treatment outcome of comprehensive genomic profiling in high grade glioma patients.Association between mutations and brain glioma grade
P2860
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P2860
Clonal analysis in recurrent astrocytic, oligoastrocytic and oligodendroglial tumors implicates IDH1- mutation as common tumor initiating event.
description
2012 nî lūn-bûn
@nan
2012年の論文
@ja
2012年論文
@yue
2012年論文
@zh-hant
2012年論文
@zh-hk
2012年論文
@zh-mo
2012年論文
@zh-tw
2012年论文
@wuu
2012年论文
@zh
2012年论文
@zh-cn
name
Clonal analysis in recurrent a ...... common tumor initiating event.
@ast
Clonal analysis in recurrent a ...... common tumor initiating event.
@en
type
label
Clonal analysis in recurrent a ...... common tumor initiating event.
@ast
Clonal analysis in recurrent a ...... common tumor initiating event.
@en
prefLabel
Clonal analysis in recurrent a ...... common tumor initiating event.
@ast
Clonal analysis in recurrent a ...... common tumor initiating event.
@en
P2093
P2860
P1433
P1476
Clonal analysis in recurrent a ...... common tumor initiating event.
@en
P2093
Astrid Nümann
Florian Stockhammer
Judith Jeuken
Julian Veelken
Jörn A Horaczek
Jürgen Kiwit
Kajetan von Eckardstein
Ulrike Lass
Wolf Mueller
P2860
P304
P356
10.1371/JOURNAL.PONE.0041298
P407
P577
2012-07-23T00:00:00Z