STAR RNA-binding protein Quaking suppresses cancer via stabilization of specific miRNA - Wikidata - awgldk - TriplyDB

STAR RNA-binding protein Quaking suppresses cancer via stabilization of specific miRNA

STAR RNA-binding protein Quaking suppresses cancer via stabilization of specific miRNA

http://www.wikidata.org/entity/Q36110907

about

Emerging functions of the Quaking RNA-binding proteins and link to human diseases RNA Binding Proteins in the miRNA Pathway Regulation of microRNA biogenesis and turnover by animals and their viruses A kinome-wide RNAi screen in Drosophila Glia reveals that the RIO kinases mediate cell proliferation and survival through TORC2-Akt signaling in glioblastoma Solution Structure of the QUA1 Dimerization Domain of pXqua, the Xenopus Ortholog of Quaking microRNAs and RNA-binding proteins: a complex network of interactions and reciprocal regulations in cancer Outside the coding genome, mammalian microRNAs confer structural and functional complexity The somatic genomic landscape of glioblastoma RNA-Binding Protein Musashi1 Is a Central Regulator of Adhesion Pathways in Glioblastoma.RNA-binding protein GLD-1/quaking genetically interacts with the mir-35 and the let-7 miRNA pathways in Caenorhabditis elegans.Qki deficiency maintains stemness of glioma stem cells in suboptimal environment by downregulating endolysosomal degradation.A cytoplasmic quaking I isoform regulates the hnRNP F/H-dependent alternative splicing pathway in myelinating glia.CAHM, a long non-coding RNA gene hypermethylated in colorectal neoplasia.MYB-QKI rearrangements in angiocentric glioma drive tumorigenicity through a tripartite mechanism.Evolutionary Dynamics of GLD-1-mRNA complexes in Caenorhabditis nematodes.The RNA-binding protein QKI suppresses cancer-associated aberrant splicing.Identifying overlapping mutated driver pathways by constructing gene networks in cancer.NF-κB induces miR-148a to sustain TGF-β/Smad signaling activation in glioblastoma.The impact of post-transcriptional regulation in the p53 network.MicroRNA biogenesis: regulating the regulators.MiR-143-3p functions as a tumor suppressor by regulating cell proliferation, invasion and epithelial-mesenchymal transition by targeting QKI-5 in esophageal squamous cell carcinoma.Determination of a Comprehensive Alternative Splicing Regulatory Network and Combinatorial Regulation by Key Factors during the Epithelial-to-Mesenchymal Transition Emerging roles of competing endogenous RNAs in cancer: insights from the regulation of PTEN QKI5-mediated alternative splicing of the histone variant macroH2A1 regulates gastric carcinogenesis.RNA-binding protein RBM24 regulates p63 expression via mRNA stability.CRAF gene fusions in pediatric low-grade gliomas define a distinct drug response based on dimerization profiles.RNA-binding protein QKI-5 inhibits the proliferation of clear cell renal cell carcinoma via post-transcriptional stabilization of RASA1 mRNA Posttranscriptional regulation of FOXO expression: microRNAs and beyond.The QKI-5 and QKI-6 RNA binding proteins regulate the expression of microRNA 7 in glial cells.Targeting of TGFβ signature and its essential component CTGF by miR-18 correlates with improved survival in glioblastoma.Quaking and miR-155 interactions in inflammation and leukemogenesis.Quaking and PTB control overlapping splicing regulatory networks during muscle cell differentiation.Gene Expression of Quaking in Sporadic Alzheimer's Disease Patients is Both Upregulated and Related to Expression Levels of Genes Involved in Amyloid Plaque and Neurofibrillary Tangle Formation.MiRNA Biogenesis and Regulation of Diseases: An Overview.Autogenous cross-regulation of Quaking mRNA processing and translation balances Quaking functions in splicing and translation.RNA Binding Protein as an Emerging Therapeutic Target for Cancer Prevention and Treatment.Roles of microRNAs and RNA-Binding Proteins in the Regulation of Colorectal Cancer Stem Cells.An RNA-binding protein, Qki5, regulates embryonic neural stem cells through pre-mRNA processing in cell adhesion signaling.The RNA-binding protein QKI5 regulates primary miR-124-1 processing via a distal RNA motif during erythropoiesis.Retrospective screening of microarray data to identify candidate IFN-inducible genes in a HTLV-1 transformed model.

P2860

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P2860

STAR RNA-binding protein Quaking suppresses cancer via stabilization of specific miRNA

http://www.wikidata.org/entity/Q36110907

description

2012 nî lūn-bûn

@nan

2012年の論文

@ja

2012年論文

@yue

2012年論文

@zh-hant

2012年論文

@zh-hk

2012年論文

@zh-mo

2012年論文

@zh-tw

2012年论文

@wuu

2012年论文

@zh

2012年论文

@zh-cn

name

STAR RNA-binding protein Quaking suppresses cancer via stabilization of specific miRNA

@ast

STAR RNA-binding protein Quaking suppresses cancer via stabilization of specific miRNA

@en

type

label

STAR RNA-binding protein Quaking suppresses cancer via stabilization of specific miRNA

@ast

STAR RNA-binding protein Quaking suppresses cancer via stabilization of specific miRNA

@en

prefLabel

STAR RNA-binding protein Quaking suppresses cancer via stabilization of specific miRNA

@ast

STAR RNA-binding protein Quaking suppresses cancer via stabilization of specific miRNA

@en

P1433

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P1433

Genes & Development

P1476

STAR RNA-binding protein Quaking suppresses cancer via stabilization of specific miRNA

@en

P2093

An-Jou Chen

http://www.w3.org/2001/XMLSchema#string

Baoli Hu

http://www.w3.org/2001/XMLSchema#string

Caroline Dong

http://www.w3.org/2001/XMLSchema#string

Hailei Zhang

http://www.w3.org/2001/XMLSchema#string

Haoqiang Ying

http://www.w3.org/2001/XMLSchema#string

Jessica Hurt

http://www.w3.org/2001/XMLSchema#string

Ji-Hye Paik

http://www.w3.org/2001/XMLSchema#string

Jian Hu

http://www.w3.org/2001/XMLSchema#string

Natalie Farny

http://www.w3.org/2001/XMLSchema#string

Richard Mortensen

http://www.w3.org/2001/XMLSchema#string

P2860

Feedback circuit among INK4 tumor suppressors constrains human glioblastoma development

Structure-function analysis of Qk1: a lethal point mutation in mouse quaking prevents homodimerization.

Function of quaking in myelination: regulation of alternative splicing.

Frequent deletions and down-regulation of micro- RNA genes miR15 and miR16 at 13q14 in chronic lymphocytic leukemia

A microRNA expression signature of human solid tumors defines cancer gene targets

Human QKI, a potential regulator of mRNA expression of human oligodendrocyte-related genes involved in schizophrenia

p53 represses c-Myc through induction of the tumor suppressor miR-145

Targeted deletion reveals essential and overlapping functions of the miR-17 through 92 family of miRNA clusters

Repression of the miR-17-92 cluster by p53 has an important function in hypoxia-induced apoptosis

Comprehensive genomic characterization defines human glioblastoma genes and core pathways

P304

1459-1472

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scholarly article

P356

10.1101/GAD.189001.112

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P433

13

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P478

26

http://www.w3.org/2001/XMLSchema#string

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P577

2012-07-01T00:00:00Z

http://www.w3.org/2001/XMLSchema#dateTime

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228103443

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22751500

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3403014

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