Activity and inhibition of prostasin and matriptase on apical and basolateral surfaces of human airway epithelial cells
about
Human cancer cells retain modest levels of enzymatically active matriptase only in extracellular milieu following induction of zymogen activationMutational tail loss is an evolutionary mechanism for liberating marapsins and other type I serine proteases from transmembrane anchors.Divergent Inhibitor Susceptibility among Airway Lumen-Accessible Tryptic ProteasesReduced sodium transport with nasal administration of the prostasin inhibitor camostat in subjects with cystic fibrosis.Human airway trypsin-like protease, a serine protease involved in respiratory diseases.Inhibition of Protease-Epithelial Sodium Channel Signaling Improves Mucociliary Function in Cystic Fibrosis Airways.Proteolytic cleavages in the extracellular domain of receptor tyrosine kinases by membrane-associated serine proteases.Matriptase shedding is closely coupled with matriptase zymogen activation and requires de novo proteolytic cleavage likely involving its own activity.Influenza A matrix protein M2 downregulates CFTR: inhibition of chloride transport by a proton channel of the viral envelope.
P2860
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P2860
Activity and inhibition of prostasin and matriptase on apical and basolateral surfaces of human airway epithelial cells
description
2012 nî lūn-bûn
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2012年の論文
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2012年論文
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2012年論文
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2012年論文
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2012年論文
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2012年論文
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name
Activity and inhibition of pro ...... human airway epithelial cells
@ast
Activity and inhibition of pro ...... human airway epithelial cells
@en
type
label
Activity and inhibition of pro ...... human airway epithelial cells
@ast
Activity and inhibition of pro ...... human airway epithelial cells
@en
prefLabel
Activity and inhibition of pro ...... human airway epithelial cells
@ast
Activity and inhibition of pro ...... human airway epithelial cells
@en
P2093
P2860
P1476
Activity and inhibition of pro ...... human airway epithelial cells
@en
P2093
Charles S Craik
Dieter C Gruenert
George H Caughey
Marina Besprozvannaya
Shilpa Nimishakavi
Wilfred W Raymond
P2860
P304
P356
10.1152/AJPLUNG.00303.2011
P577
2012-05-11T00:00:00Z