On the remarkable antitumor properties of fludelone: how we got there.
about
Nature's bounty - drug discovery from the seaChemistry and biology of resorcylic acid lactonesAn "aprotic" Tamao oxidation/syn-selective tautomerization reaction for the efficient synthesis of the C1-C9 fragment of fludeloneDiverted total synthesis leads to the generation of promising cell-migration inhibitors for treatment of tumor metastasis: in vivo and mechanistic studies on the migrastatin core ether analogDiamond nanowires for highly sensitive matrix-free mass spectrometry analysis of small molecules.Total syntheses and biological reassessment of lactimidomycin, isomigrastatin and congener glutarimide antibiotics.(+)-Discodermolide: Total Synthesis, Construction of Novel Analogues, and Biological EvaluationNatural and engineered biosynthesis of fluorinated natural products.Toward more "ideal" polyketide natural product synthesis: a step-economical synthesis of zincophorin methyl esterMultifaceted cytoprotection by synthetic polyacetylenes inspired by the ginseng-derived natural product, panaxytriol.Diverted Total Synthesis of Promysalin Analogs Demonstrates That an Iron-Binding Motif Is Responsible for Its Narrow-Spectrum Antibacterial ActivitySynthetic studies toward (+)-cortistatin AConstructing molecular complexity and diversity: total synthesis of natural products of biological and medicinal importance.Strategies for the Optimization of Natural Leads to Anticancer Drugs or Drug Candidates.The winding pathway to erythropoietin along the chemistry-biology frontier: a success at last.Anticancer drugs from nature--natural products as a unique source of new microtubule-stabilizing agents.Therapeutic effect against human xenograft tumors in nude mice by the third generation microtubule stabilizing epothilones.Isolation and Reactivity of Trifluoromethyl Iodonium Salts.Palladium-catalyzed transformations of salvinorin A, a neoclerodane diterpene from Salvia divinorum.Sequential self-assembly in metal-organic frameworks.Allylic structures in cancer drugs and body metabolites that control cell life and death.Efficient and selective formation of macrocyclic disubstituted Z alkenes by ring-closing metathesis (RCM) reactions catalyzed by Mo- or W-based monoaryloxide pyrrolide (MAP) complexes: applications to total syntheses of epilachnene, yuzu lactone, amPreparation, modification, and evaluation of cruentaren A and analogues.Total synthesis and biological assessment of benzimidazole-based analogues of epothilone A: ambivalent effects on cancer cell growth inhibition.Direct C-H trifluoromethylation of di- and trisubstituted alkenes by photoredox catalysis.Molybdenum-based complexes with two aryloxides and a pentafluoroimido ligand: catalysts for efficient Z-selective synthesis of a macrocyclic trisubstituted alkene by ring-closing metathesisChemo- and Stereoselective Cross Rauhut-Currier-Type Reaction of Tri-substituted Alkenes Containing Trifluoromethyl Groups.The Total Synthesis of Epothilone D as a Yardstick for Probing New Methodologies.Natural Products as Platforms To Overcome Antibiotic Resistance.Synthesis and Evaluation of a Linkable Functional Group-Equipped Analogue of the Epothilones.Photoredox-Catalyzed Stereoselective Conversion of Alkynes into Tetrasubstituted Trifluoromethylated Alkenes.The mechanism of copper-catalyzed oxytrifluoromethylation of allylamines with CO2: a computational studyPreparative, in vitro biocatalysis of triketide lactone chiral building blocks.Efficient Synthesis and Biological Evaluation of Topopyrone C Derivatives
P2860
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P2860
On the remarkable antitumor properties of fludelone: how we got there.
description
2005 nî lūn-bûn
@nan
2005年の論文
@ja
2005年論文
@yue
2005年論文
@zh-hant
2005年論文
@zh-hk
2005年論文
@zh-mo
2005年論文
@zh-tw
2005年论文
@wuu
2005年论文
@zh
2005年论文
@zh-cn
name
On the remarkable antitumor properties of fludelone: how we got there.
@ast
On the remarkable antitumor properties of fludelone: how we got there.
@en
type
label
On the remarkable antitumor properties of fludelone: how we got there.
@ast
On the remarkable antitumor properties of fludelone: how we got there.
@en
prefLabel
On the remarkable antitumor properties of fludelone: how we got there.
@ast
On the remarkable antitumor properties of fludelone: how we got there.
@en
P2093
P356
P1476
On the remarkable antitumor properties of fludelone: how we got there.
@en
P2093
Alexey Rivkin
Samuel J Danishefsky
Ting-Chao Chou
P304
P356
10.1002/ANIE.200461751
P407
P577
2005-05-01T00:00:00Z