NEMO inhibits programmed necrosis in an NFκB-independent manner by restraining RIP1.
about
Poly-ubiquitination in TNFR1-mediated necroptosisProgrammed necrosis in the cross talk of cell death and inflammationRIPK3 contributes to TNFR1-mediated RIPK1 kinase-dependent apoptosis in conditions of cIAP1/2 depletion or TAK1 kinase inhibitionNEMO Prevents Steatohepatitis and Hepatocellular Carcinoma by Inhibiting RIPK1 Kinase Activity-Mediated Hepatocyte ApoptosisRIP kinases: key decision makers in cell death and innate immunity.CYLD deubiquitinates RIP1 in the TNFα-induced necrosome to facilitate kinase activation and programmed necrosis.Protein-Binding Function of RNA-Dependent Protein Kinase Promotes Proliferation through TRAF2/RIP1/NF-κB/c-Myc Pathway in Pancreatic β cellsBrain endothelial TAK1 and NEMO safeguard the neurovascular unitRecruitment of A20 by the C-terminal domain of NEMO suppresses NF-κB activation and autoinflammatory disease.NEMO Prevents RIP Kinase 1-Mediated Epithelial Cell Death and Chronic Intestinal Inflammation by NF-κB-Dependent and -Independent Functions.Distinct Activation Mechanisms of NF-κB Regulator Inhibitor of NF-κB Kinase (IKK) by Isoforms of the Cell Death Regulator Cellular FLICE-like Inhibitory Protein (cFLIP).CYLD Proteolysis Protects Macrophages from TNF-Mediated Auto-necroptosis Induced by LPS and Licensed by Type I IFN.RIP3: a molecular switch for necrosis and inflammation.Opposing effect of EGFRWT on EGFRvIII-mediated NF-κB activation with RIP1 as a cell death switch.Non-conventional functions for NF-κB members: the dark side of NF-κB.Cloaked in ubiquitin, a killer hides in plain sight: the molecular regulation of RIPK1.Cancer and necroptosis: friend or foe?Necroptosis-independent signaling by the RIP kinases in inflammation.More to Life than NF-κB in TNFR1 SignalingEffects of silencing RIP1 with siRNA on the biological behavior of the LoVo human colon cancer cell lineComplex Pathologic Roles of RIPK1 and RIPK3: Moving Beyond Necroptosis.The interplay of IKK, NF-κB and RIPK1 signaling in the regulation of cell death, tissue homeostasis and inflammation.Transplantation from a symptomatic carrier sister restores host defenses but does not prevent colitis in NEMO deficiency.Positive and negative phosphorylation regulates RIP1- and RIP3-induced programmed necrosisNEMO regulates a cell death switch in TNF signaling by inhibiting recruitment of RIPK3 to the cell death-inducing complex II.RIP1 comes back to life as a cell death regulator in TNFR1 signaling.MK2 phosphorylation of RIPK1 regulates TNF-mediated cell death.RIPK1 is deubiquitinatedSomatic mosaicism of a novel IKBKG mutation in a male patient with incontinentia pigmenti.
P2860
Q26749315-0B89C2B0-1BA9-4B87-BA3B-863697C66587Q27026709-A1CE0440-8297-4AB5-8843-788D28B7CDEAQ28295435-199366C7-9042-49E9-8104-CCA39A8C0596Q28593092-1CF67FF3-FF8E-4765-9FDB-4AC912EFB606Q34924104-0EA67EDF-0A9B-4CDA-BBFA-3599AAC4F2C2Q35009699-82453B77-F316-4CE0-8BEF-1737D44F4254Q35707141-BF707403-E35C-42C4-B974-D61CC4D1F0FDQ36080694-783A2F88-BAAD-412C-A920-D7BFA544CE86Q36598807-20FC00B8-0907-44DD-B3AC-3DC147937F92Q36718219-167B180A-A602-4346-B100-289782C796D4Q36755072-BBEAF316-7E03-45E9-9AC3-66A50D94CF0FQ37008848-74A02AF9-CD21-4B31-B1BC-2ADDD7CDB633Q37098143-E4A889E1-FDE8-4E0B-8FEC-11416A6B3744Q37192269-CDE1517E-5A6D-48D8-AE22-4B4C6A1A456BQ38224263-3F013901-654F-43AF-B6F6-DEE8825FC14EQ38530635-CBC1F5E1-DEBD-43C3-A800-B553D53044A1Q38799139-B2C7A8DE-80FE-4B16-8478-4FD81F00CF92Q38799149-4DFC0E01-2DE2-414F-9148-28FA63BF10B2Q38899361-50D8201B-951A-4B08-8418-B50439D34378Q38984420-18815E3E-9156-4578-86E8-AD7502C6800BQ39105381-89DD0AE1-205F-4062-A050-7E32BCFC4259Q39277505-4B39FB03-8A15-4ACE-B814-C4E454AE9C36Q40817291-93E68F14-5C4B-4024-A565-BC2627AABBBCQ42153354-8FC202DF-A920-4CFD-9E1C-10D83469A25CQ42369047-642F420A-CD39-4BE9-B428-B407FBA9D026Q42661602-760FF4FA-5995-47AC-8AF8-58B26BC5BB35Q47787256-AE73FAEC-0200-4F0A-B81F-7DC1A8D967ADQ50299362-E86A64E6-8088-4C07-9269-FF295290E044Q53518229-6566BA92-3979-4C22-BD11-653F0FD667A7
P2860
NEMO inhibits programmed necrosis in an NFκB-independent manner by restraining RIP1.
description
2012 nî lūn-bûn
@nan
2012年の論文
@ja
2012年論文
@yue
2012年論文
@zh-hant
2012年論文
@zh-hk
2012年論文
@zh-mo
2012年論文
@zh-tw
2012年论文
@wuu
2012年论文
@zh
2012年论文
@zh-cn
name
NEMO inhibits programmed necrosis in an NFκB-independent manner by restraining RIP1.
@ast
NEMO inhibits programmed necrosis in an NFκB-independent manner by restraining RIP1.
@en
type
label
NEMO inhibits programmed necrosis in an NFκB-independent manner by restraining RIP1.
@ast
NEMO inhibits programmed necrosis in an NFκB-independent manner by restraining RIP1.
@en
prefLabel
NEMO inhibits programmed necrosis in an NFκB-independent manner by restraining RIP1.
@ast
NEMO inhibits programmed necrosis in an NFκB-independent manner by restraining RIP1.
@en
P2093
P2860
P1433
P1476
NEMO inhibits programmed necrosis in an NFκB-independent manner by restraining RIP1.
@en
P2093
Adrian T Ting
Diana Legarda
Hidenori Hase
Marie Anne O'Donnell
P2860
P304
P356
10.1371/JOURNAL.PONE.0041238
P407
P577
2012-07-26T00:00:00Z