Bifunctional crosslinking ligands for transthyretin

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Modifications of the 7-Hydroxyl Group of the Transthyretin Ligand Luteolin Provide Mechanistic Insights into Its Binding Properties and High Plasma Specificity Emerging therapeutic targets currently under investigation for the treatment of systemic amyloidosis.

P2860

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P2860

Bifunctional crosslinking ligands for transthyretin

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http://www.wikidata.org/entity/Q36122263

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2015 nî lūn-bûn

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2015年の論文

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2015年論文

@yue

2015年論文

@zh-hant

2015年論文

@zh-hk

2015年論文

@zh-mo

2015年論文

@zh-tw

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2015年论文

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2015年论文

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name

Bifunctional crosslinking ligands for transthyretin

@ast

Bifunctional crosslinking ligands for transthyretin

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type

Item

label

Bifunctional crosslinking ligands for transthyretin

@ast

Bifunctional crosslinking ligands for transthyretin

@en

prefLabel

Bifunctional crosslinking ligands for transthyretin

@ast

Bifunctional crosslinking ligands for transthyretin

@en

P1476

Bifunctional crosslinking ligands for transthyretin

@en

P2093

Antonio K Vong

http://www.w3.org/2001/XMLSchema#string

Christopher J Swain

http://www.w3.org/2001/XMLSchema#string

Glenys A Tennent

http://www.w3.org/2001/XMLSchema#string

Graham W Taylor

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Joanne R Thurston

http://www.w3.org/2001/XMLSchema#string

Martin D Smith

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P Patrizia Mangione

http://www.w3.org/2001/XMLSchema#string

Robert J Broadbridge

http://www.w3.org/2001/XMLSchema#string

Stephan Ellmerich

http://www.w3.org/2001/XMLSchema#string

Stephen P Wood

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P2860

Benzoxazoles as transthyretin amyloid fibril inhibitors: synthesis, evaluation, and mechanism of action

Diflunisal analogues stabilize the native state of transthyretin. Potent inhibition of amyloidogenesis

Trapping of palindromic ligands within native transthyretin prevents amyloid formation

Targeted pharmacological depletion of serum amyloid P component for treatment of human amyloidosis

Disruption of the transthyretin gene results in mice with depressed levels of plasma retinol and thyroid hormone

Ion mobility-mass spectrometry reveals long-lived, unfolded intermediates in the dissociation of protein complexes.

Safety and efficacy of long-term diflunisal administration in hereditary transthyretin (ATTR) amyloidosis.

Senile systemic amyloidosis: clinical features at presentation and outcome.

Variant-sequence transthyretin (isoleucine 122) in late-onset cardiac amyloidosis in black Americans.

Senile systemic amyloidosis presenting with heart failure: a comparison with light chain-associated amyloidosis.

P304

150105

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P31

scholarly article

P356

10.1098/RSOB.150105

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P433

http://www.w3.org/2001/XMLSchema#string

P478

http://www.w3.org/2001/XMLSchema#string

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2015-09-01T00:00:00Z

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282153384

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26400472

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P932

4593668

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Bifunctional crosslinking ligands for transthyretin

about

P2860

P2860

Bifunctional crosslinking ligands for transthyretin

description

name

type

label

prefLabel

P1433

P1476

P2093

P2860

P304

P31

P356

P433

P478

P50

P577

P5875

P698

P932

P356

P1433

P1476

P2093

P2860

P304

P31

P356

P433

P478

P50

P577

P5875

P698

P932