SDF-1/CXCR4 signaling induces pancreatic cancer cell invasion and epithelial-mesenchymal transition in vitro through non-canonical activation of Hedgehog pathway
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Hedgehog signaling: modulation of cancer properies and tumor mircroenvironmentEmerging roles of PDGF-D in EMT progression during tumorigenesisMolecular mechanism underlying lymphatic metastasis in pancreatic cancerPersistent activation of pancreatic stellate cells creates a microenvironment favorable for the malignant behavior of pancreatic ductal adenocarcinomaConcise Review: Stem Cells in Pancreatic Cancer: From Concept to TranslationDynamic mast cell-stromal cell interactions promote growth of pancreatic cancer.Pancreatic stellate cells promote hapto-migration of cancer cells through collagen I-mediated signalling pathway.Effects of inhibition of hedgehog signaling on cell growth and migration of uveal melanoma cells.miR-539 inhibits FSCN1 expression and suppresses hepatocellular carcinoma migration and invasion.Chemokine (C‑C motif) ligand 21/C‑C chemokine receptor type 7 triggers migration and invasion of human lung cancer cells by epithelial‑mesenchymal transition via the extracellular signal‑regulated kinase signaling pathway.SDF-1 in Mammary Fibroblasts of Bovine with Mastitis Induces EMT and Inflammatory Response of Epithelial CellsStroma-derived Fibrinogen-like Protein 2 Activates Cancer-associated Fibroblasts to Promote Tumor Growth in Lung CancerThe N-terminal polypeptide derived from viral macrophage inflammatory protein II reverses breast cancer epithelial-to-mesenchymal transition via a PDGFRα-dependent mechanismFibroblast heterogeneity in the cancer wound.Sonic hedgehog-Gli1 signaling pathway regulates the epithelial mesenchymal transition (EMT) by mediating a new target gene, S100A4, in pancreatic cancer cellsRan GTPase protein promotes metastasis and invasion in pancreatic cancer by deregulating the expression of AR and CXCR4.CXCL12-CXCR7 axis contributes to the invasive phenotype of pancreatic cancer.Blockade of CXCL12/CXCR4 signaling inhibits intrahepatic cholangiocarcinoma progression and metastasis via inactivation of canonical Wnt pathway.Chemokine ligand 20 enhances progression of hepatocellular carcinoma via epithelial-mesenchymal transitionOverexpression of Nodal induces a metastatic phenotype in pancreatic cancer cells via the Smad2/3 pathwayStromal-derived factor-1α/CXCL12-CXCR4 chemotactic pathway promotes perineural invasion in pancreatic cancer.Dermal fibroblast expression of stromal cell-derived factor-1 (SDF-1) promotes epidermal keratinocyte proliferation in normal and diseased skin.Inhibition of cyclooxygenase-2 prevents intra-abdominal adhesions by decreasing activity of peritoneal fibroblastsAMD3100 reduces CXCR4-mediated survival and metastasis of osteosarcoma by inhibiting JNK and Akt, but not p38 or Erk1/2, pathways in in vitro and mouse experiments.IL-8 confers resistance to EGFR inhibitors by inducing stem cell properties in lung cancer.A novel biphenyl urea derivate inhibits the invasion of breast cancer through the modulation of CXCR4Targeting the Hedgehog signaling pathway in cancer: beyond Smoothened.Chemotherapy induces adaptive drug resistance and metastatic potentials via phenotypic CXCR4-expressing cell state transition in ovarian cancerLipoxin A4 Attenuates Cell Invasion by Inhibiting ROS/ERK/MMP Pathway in Pancreatic CancerCurcumin inhibits cancer-associated fibroblast-driven prostate cancer invasion through MAOA/mTOR/HIF-1α signalingWnt/β-catenin pathway is required for epithelial to mesenchymal transition in CXCL12 over expressed breast cancer cellsNef-M1, a peptide antagonist of CXCR4, inhibits tumor angiogenesis and epithelial‑to‑mesenchymal transition in colon and breast cancers.Hedgehog signaling regulates hypoxia induced epithelial to mesenchymal transition and invasion in pancreatic cancer cells via a ligand-independent mannerHedgehog pathway is involved in nitidine chloride induced inhibition of epithelial-mesenchymal transition and cancer stem cells-like properties in breast cancer cellsTargeted silencing of CXCR4 inhibits epithelial-mesenchymal transition in oral squamous cell carcinoma.CCL20 mediates RANK/RANKL-induced epithelial-mesenchymal transition in endometrial cancer cellsLoss of Merlin induces metabolomic adaptation that engages dependence on Hedgehog signaling.Galectin-1 induces invasion and the epithelial-mesenchymal transition in human gastric cancer cells via non-canonical activation of the hedgehog signaling pathway.α-Mangostin inhibits hypoxia-driven ROS-induced PSC activation and pancreatic cancer cell invasion.Nonclassical hedgehog-GLI signaling and its clinical implications.
P2860
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P2860
SDF-1/CXCR4 signaling induces pancreatic cancer cell invasion and epithelial-mesenchymal transition in vitro through non-canonical activation of Hedgehog pathway
description
2012 nî lūn-bûn
@nan
2012年の論文
@ja
2012年論文
@yue
2012年論文
@zh-hant
2012年論文
@zh-hk
2012年論文
@zh-mo
2012年論文
@zh-tw
2012年论文
@wuu
2012年论文
@zh
2012年论文
@zh-cn
name
SDF-1/CXCR4 signaling induces ...... activation of Hedgehog pathway
@ast
SDF-1/CXCR4 signaling induces ...... activation of Hedgehog pathway
@en
type
label
SDF-1/CXCR4 signaling induces ...... activation of Hedgehog pathway
@ast
SDF-1/CXCR4 signaling induces ...... activation of Hedgehog pathway
@en
prefLabel
SDF-1/CXCR4 signaling induces ...... activation of Hedgehog pathway
@ast
SDF-1/CXCR4 signaling induces ...... activation of Hedgehog pathway
@en
P2093
P2860
P1433
P1476
SDF-1/CXCR4 signaling induces ...... activation of Hedgehog pathway
@en
P2093
Fengfei Wang
Jianjun Lei
Kruttika Bhat
Qingyong Ma
Qinhong Xu
Wanxing Duan
Zheng Wang
P2860
P304
P356
10.1016/J.CANLET.2012.02.035
P407
P50
P577
2012-03-23T00:00:00Z