Coupling cellular localization and function of checkpoint kinase 1 (Chk1) in checkpoints and cell viability
about
DNA damage control: regulation and functions of checkpoint kinase 1Roles of Chk1 in cell biology and cancer therapyLoss of Nek11 Prevents G2/M Arrest and Promotes Cell Death in HCT116 Colorectal Cancer Cells Exposed to Therapeutic DNA Damaging AgentsThe interaction between checkpoint kinase 1 (Chk1) and the minichromosome maintenance (MCM) complex is required for DNA damage-induced Chk1 phosphorylation.The fork and the kinase: a DNA replication tale from a CHK1 perspective.Phosphorylation of Minichromosome Maintenance 3 (MCM3) by Checkpoint Kinase 1 (Chk1) Negatively Regulates DNA Replication and Checkpoint Activation.Checkpoint kinase1 (CHK1) is an important biomarker in breast cancer having a role in chemotherapy responseKey mediators of somatic ATR signaling localize to unpaired chromosomes in spermatocytes.Chk1 Activation Protects Rad9A from Degradation as Part of a Positive Feedback Loop during Checkpoint Signalling.A novel Chk1-binding peptide that enhances genotoxic sensitivity through the cellular redistribution of nuclear Chk1.Promoter hijack reveals pericentrin functions in mitosis and the DNA damage response.Candidate tumor suppressor BTG3 maintains genomic stability by promoting Lys63-linked ubiquitination and activation of the checkpoint kinase CHK1Conformational Change of Human Checkpoint Kinase 1 (Chk1) Induced by DNA Damage.Regulatory cross-talk determines the cellular levels of 53BP1 protein, a critical factor in DNA repair.Untangling the ATR-CHEK1 network for prognostication, prediction and therapeutic target validation in breast cancer.Chk1-Mad2 interaction: a crosslink between the DNA damage checkpoint and the mitotic spindle checkpoint.Chk1 Promotes DNA Damage Response Bypass following Oxidative Stress in a Model of Hydrogen Peroxide-Associated Ulcerative Colitis through JNK Inactivation and Chromatin Binding.Chk1 phosphorylated at serine345 is a predictor of early local recurrence and radio-resistance in breast cancerThe ATM and Rad3-related (ATR) Protein Kinase Pathway is Activated by Herpes Simplex Virus 1 (HSV-1) and Required for Efficient Viral Replication.Intramolecular autoinhibition of checkpoint kinase 1 is mediated by conserved basic motifs of the C-terminal kinase-associated 1 domain.Effects of low-intensity ultrasound combined with low-dose carboplatin in an orthotopic hamster model of tongue cancer: A preclinical study.Myosin 16 levels fluctuate during the cell cycle and are downregulated in response to DNA replication stress.A high content, high throughput cellular thermal stability assay for measuring drug-target engagement in living cells.Melanoma LAMP-2C Modulates Tumor Growth and Autophagy
P2860
Q28083686-9AD5624D-4CF0-4E11-9C4D-78EB57357692Q28289548-A7ADF80F-8C1A-41AB-81F3-803D4ECB92C9Q28550493-E38481AD-FCFD-4AF5-B27B-1661333D113AQ34107413-DC20388C-3A7C-41BE-93D8-7E867E0FFEECQ35205026-FB87CD79-C4EB-4E8E-BD23-C50E22F53209Q35583204-04BF84F2-4B90-4468-A4CA-BD1B44582CEAQ35678658-9298C8D0-DA00-4A02-880C-50190ADE7025Q35713281-2C4BA31F-F1C1-4073-9419-E47E82C468D3Q35867102-34C56B4D-0B3C-4877-B5AB-01094C3769C9Q36233746-8BDD2C8A-9CBE-4052-998D-96CD31782E66Q36674345-F10541CE-1C06-4B0C-8154-7D57A1B2BA61Q36762557-9EC85D38-389B-46B9-A461-BA279E1A5DE0Q37065840-AB6F8877-2138-46CC-B099-92E17231D39FQ38932240-EC3EEDC2-AB0A-4879-A27E-5B787D919958Q38932758-E8A09250-8DB5-431A-8F64-E2C2689646C7Q40483960-3AD0B495-8E78-4B92-A45F-C555C8F8AB0BQ41079709-86B8C728-2C98-403B-9A23-A49C9D0B2162Q41137374-4AA64DEA-71F9-40BB-AD0A-4131F6B2303CQ47269203-7CBF0C07-918C-4A17-9BF6-9876295AF1E2Q47708869-4AC2DAFB-EC93-464E-ABFC-9A405C8A3FC4Q50047549-C21C767A-0B50-4FE3-A2DB-77118ED17D55Q51062791-4DF9840D-9D7A-4872-BA2C-99D1485AF773Q52607490-B3598D2A-C61B-4FBF-BFB9-BEAFA1E0E21BQ58694266-A59E9E37-114A-4387-B22A-073CC7710F1B
P2860
Coupling cellular localization and function of checkpoint kinase 1 (Chk1) in checkpoints and cell viability
description
2012 nî lūn-bûn
@nan
2012年の論文
@ja
2012年論文
@yue
2012年論文
@zh-hant
2012年論文
@zh-hk
2012年論文
@zh-mo
2012年論文
@zh-tw
2012年论文
@wuu
2012年论文
@zh
2012年论文
@zh-cn
name
Coupling cellular localization ...... checkpoints and cell viability
@ast
Coupling cellular localization ...... checkpoints and cell viability
@en
type
label
Coupling cellular localization ...... checkpoints and cell viability
@ast
Coupling cellular localization ...... checkpoints and cell viability
@en
prefLabel
Coupling cellular localization ...... checkpoints and cell viability
@ast
Coupling cellular localization ...... checkpoints and cell viability
@en
P2093
P2860
P356
P1476
Coupling cellular localization ...... checkpoints and cell viability
@en
P2093
Jingna Wang
Xiangzi Han
Xiujing Feng
Youwei Zhang
Zhenghe Wang
P2860
P304
25501-25509
P356
10.1074/JBC.M112.350397
P407
P577
2012-06-11T00:00:00Z