MiniCD4 protein resistance mutations affect binding to the HIV-1 gp120 CD4 binding site and decrease entry efficiency.
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MiniCD4 microbicide prevents HIV infection of human mucosal explants and vaginal transmission of SHIV(162P3) in cynomolgus macaquesStructural Basis for Highly Effective HIV-1 Neutralization by CD4-Mimetic Miniproteins Revealed by 1.5 Å Cocrystal Structure of gp120 and M48U1Differences in the Selection Bottleneck between Modes of Sexual Transmission Influence the Genetic Composition of the HIV-1 Founder VirusM48U1 CD4 mimetic has a sustained inhibitory effect on cell-associated HIV-1 by attenuating virion infectivity through gp120 shedding.HIV-1 Env gp120 structural determinants for peptide triazole dual receptor site antagonism.CD4-mimetic sulfopeptide conjugates display sub-nanomolar anti-HIV-1 activity and protect macaques against a SHIV162P3 vaginal challenge.Driving HIV-1 into a Vulnerable Corner by Taking Advantage of Viral Adaptation and Evolution.Escape from human immunodeficiency virus type 1 (HIV-1) entry inhibitors.
P2860
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P2860
MiniCD4 protein resistance mutations affect binding to the HIV-1 gp120 CD4 binding site and decrease entry efficiency.
description
2012 nî lūn-bûn
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2012年の論文
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2012年論文
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2012年論文
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2012年論文
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2012年論文
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2012年論文
@zh-tw
2012年论文
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2012年论文
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2012年论文
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name
MiniCD4 protein resistance mut ...... and decrease entry efficiency.
@ast
MiniCD4 protein resistance mut ...... and decrease entry efficiency.
@en
type
label
MiniCD4 protein resistance mut ...... and decrease entry efficiency.
@ast
MiniCD4 protein resistance mut ...... and decrease entry efficiency.
@en
prefLabel
MiniCD4 protein resistance mut ...... and decrease entry efficiency.
@ast
MiniCD4 protein resistance mut ...... and decrease entry efficiency.
@en
P2093
P2860
P356
P1433
P1476
MiniCD4 protein resistance mut ...... and decrease entry efficiency.
@en
P2093
Guido Vanham
Johan Michiels
Katleen Vereecken
Katrijn Grupping
Kevin K Ariën
Leo Heyndrickx
Loïc Martin
Pascal Kessler
Philippe Selhorst
P2860
P2888
P356
10.1186/1742-4690-9-36
P577
2012-05-02T00:00:00Z
P5875
P6179
1018157155